Cannabinoid CB2 receptors are upregulated via bivalent histone modifications and control primary afferent input to the spinal cord in neuropathic pain

por Ghosh, Krishna, Zhang, Guang-Fen, Chen, Hong, Chen, Shao-Rui, Pan, Hui-Lin
Publicado 2022

The JMJD3 histone demethylase inhibitor GSK-J1 ameliorates lipopolysaccharide-induced inflammation in a mastitis model

por Wang, Jing-Jing, Wang, Xia, Xian, Yin-Er, Chen, Zi-Qing, Sun, You-Peng, Fu, Yi-Wu, Wu, Zhi-Kai, Li, Pei-Xuan, Zhou, Er-Shun, Yang, Zheng-Tao
Publicado 2022

Human UFSP1 translated from an upstream near-cognate initiation codon functions as an active UFM1-specific protease

por Liang, Qian, Jin, Yaqi, Xu, Shiwen, Zhou, Junzhi, Mao, Jian, Ma, Xiaohe, Wang, Miao, Cong, Yu-Sheng
Publicado 2022

Proteomic elucidation of the targets and primary functions of the picornavirus 2A protease

por Serganov, Artem A., Udi, Yael, Stein, Milana E., Patel, Valay, Fridy, Peter C., Rice, Charles M., Saeed, Mohsan, Jacobs, Erica Y., Chait, Brian T., Rout, Michael P.
Publicado 2022

Genetic validation of Aspergillus fumigatus phosphoglucomutase as a viable therapeutic target in invasive aspergillosis

por Yan, Kaizhou, Stanley, Mathew, Kowalski, Bartosz, Raimi, Olawale G., Ferenbach, Andrew T., Wei, Pingzhen, Fang, Wenxia, van Aalten, Daan M.F.
Publicado 2022

Allosteric coupling between transmembrane segment 4 and the selectivity filter of TALK1 potassium channels regulates their gating by extracellular pH

por Tsai, Wen-Hao, Grauffel, Cédric, Huang, Ming-Yueh, Postić, Sandra, Rupnik, Marjan Slak, Lim, Carmay, Yang, Shi-Bing
Publicado 2022

Deformation of caveolae impacts global transcription and translation processes through relocalization of cavin-1

por Qifti, Androniqi, Balaji, Shravani, Scarlata, Suzanne
Publicado 2022

Zinc transport via ZNT5-6 and ZNT7 is critical for cell surface glycosylphosphatidylinositol-anchored protein expression

por Wagatsuma, Takumi, Shimotsuma, Keiko, Sogo, Akiko, Sato, Risa, Kubo, Naoya, Ueda, Sachiko, Uchida, Yasuo, Kinoshita, Masato, Kambe, Taiho
Publicado 2022

Binding of the erlin1/2 complex to the third intralumenal loop of IP(3)R1 triggers its ubiquitin-proteasomal degradation

por Gao, Xiaokong, Bonzerato, Caden G., Wojcikiewicz, Richard J.H.
Publicado 2022

Validation of a multiplexed and targeted lipidomics assay for accurate quantification of lipidomes

por Zhang, Nanyan Rena, Hatcher, Nathan G., Ekroos, Kim, Kedia, Komal, Kandebo, Monika, Marcus, Jacob N., Smith, Sean M., Bateman, Kevin P., Spellman, Daniel S.
Publicado 2022

Human C1orf27 protein interacts with α(2A)-adrenergic receptor and regulates its anterograde transport

por Xu, Xin, Wu, Guangyu
Publicado 2022

Analysis of functional surfaces on the actin nucleation promoting factor Dip1 required for Arp2/3 complex activation and endocytic actin network assembly

por Liu, Su-Ling, Narvaez-Ortiz, Heidy Y., Miner, Matt, Kiemel, Jack, Oberhelman, Nicholas, Watt, April, Wagner, Andrew R., Luan, Qing, Helgeson, Luke A., Nolen, Brad J.
Publicado 2022

eEF2K Activity Determines Synergy to Cotreatment of Cancer Cells With PI3K and MEK Inhibitors

por Hijazi, Maruan, Casado, Pedro, Akhtar, Nosheen, Alvarez-Teijeiro, Saul, Rajeeve, Vinothini, Cutillas, Pedro R.
Publicado 2022

Isomeric lipid signatures reveal compartmentalized fatty acid metabolism in cancer

por Young, Reuben S.E., Bowman, Andrew P., Tousignant, Kaylyn D., Poad, Berwyck L.J., Gunter, Jennifer H., Philp, Lisa K., Nelson, Colleen C., Ellis, Shane R., Heeren, Ron M.A., Sadowski, Martin C., Blanksby, Stephen J.
Publicado 2022

Interval-Based Secretomics Unravels Acute-Phase Response in Hepatocyte Model Systems

por Knecht, Sascha, Eberl, H. Christian, Bantscheff, Marcus
Publicado 2022

COVID-19: lipid disruption is pushing the envelope

por FitzGerald, Garret A.
Publicado 2022

The cryo-EM structure of the S-layer deinoxanthin-binding complex of Deinococcus radiodurans informs properties of its environmental interactions

por Farci, Domenica, Haniewicz, Patrycja, de Sanctis, Daniele, Iesu, Luca, Kereïche, Sami, Winterhalter, Mathias, Piano, Dario
Publicado 2022

Factor inhibiting HIF can catalyze two asparaginyl hydroxylations in VNVN motifs of ankyrin fold proteins

por Leissing, Thomas M., Hardy, Adam P., Chan, Hokfung, Wang, Yihua, Tumber, Anthony, Chowdhury, Rasheduzzaman, Feng, Tianshu, Coleman, Mathew L., Cockman, Matthew E., Kramer, Holger B., Berridge, Georgina, Fischer, Roman, Kessler, Benedikt M., Ratcliffe, Peter J., Lu, Xin, Schofield, Christopher J.
Publicado 2022

Neuronal growth regulator 1 promotes adipocyte lipid trafficking via interaction with CD36

por Yoo, Ara, Joo, Yeonhee, Cheon, Yeongmi, Lee, Sung Joong, Lee, Soojin
Publicado 2022

The effects of cardiolipin on the structural dynamics of the mitochondrial ADP/ATP carrier in its cytosol-open state

por Yi, Qiuzi, Yao, Shihao, Ma, Boyuan, Cang, Xiaohui
Publicado 2022