Structure-based interface engineering methodology in designing a thermostable amylose-forming transglucosylase

por Tian, Yuqing, Hou, Xiaodong, Ni, Dawei, Xu, Wei, Guang, Cuie, Zhang, Wenli, Chen, Qiuming, Rao, Yijian, Mu, Wanmeng
Publicado 2022

Comparative analysis defines a broader FMRFamide-gated sodium channel family and determinants of neuropeptide sensitivity

por Dandamudi, Mowgli, Hausen, Harald, Lynagh, Timothy
Publicado 2022

Protein interaction networks in neurodegenerative diseases: From physiological function to aggregation

por Calabrese, Gaetano, Molzahn, Cristen, Mayor, Thibault
Publicado 2022

Whole picture of human stratum corneum ceramides, including the chain-length diversity of long-chain bases

por Suzuki, Madoka, Ohno, Yusuke, Kihara, Akio
Publicado 2022

Saroglitazar is noninferior to fenofibrate in reducing triglyceride levels in hypertriglyceridemic patients in a randomized clinical trial

por Rodriguez-Gutierrez, Rene, González, Jose Gerardo, Parmar, Deven, Shaikh, Farheen., Cruz-López, Pio
Publicado 2022

Membrane-bound O-acyltransferase 7 (MBOAT7)-driven phosphatidylinositol remodeling in advanced liver disease

por Varadharajan, Venkateshwari, Massey, William J., Brown, J. Mark
Publicado 2022

Clinical, genetic, and functional characterization of the glycine receptor β-subunit A455P variant in a family affected by hyperekplexia syndrome

por Aboheimed, Ghada I., AlRasheed, Maha M., Almudimeegh, Sultan, Peña-Guerra, Karla A., Cardona-Londoño, Kelly J., Salih, Mustafa A., Seidahmed, Mohammed Z., Al-Mohanna, Futwan, Colak, Dilek, Harvey, Robert J., Harvey, Kirsten, Arold, Stefan T., Kaya, Namik, Ruiz, Arnaud J.
Publicado 2022

Interplay between H3K36me3, methyltransferase SETD2, and mismatch recognition protein MutSα facilitates processing of oxidative DNA damage in human cells

por Guo, Sida, Fang, Jun, Xu, Weizhi, Ortega, Janice, Liu, Chang-Yi, Gu, Liya, Chang, Zhijie, Li, Guo-Min
Publicado 2022

Guanine nucleotide exchange factor DOCK11-binding peptide fused with a single chain antibody inhibits hepatitis B virus infection and replication

por Ide, Mayuko, Tabata, Noriko, Yonemura, Yuko, Shirasaki, Takayoshi, Murai, Kazuhisa, Wang, Ying, Ishida, Atsuya, Okada, Hikari, Honda, Masao, Kaneko, Shuichi, Doi, Nobuhide, Ito, Satoru, Yanagawa, Hiroshi
Publicado 2022

Identification and Analysis of Six Phosphorylation Sites Within the Xenopus laevis Linker Histone H1.0 C-Terminal Domain Indicate Distinct Effects on Nucleosome Structure

por Hao, Fanfan, Mishra, Laxmi N., Jaya, Prasoon, Jones, Richard, Hayes, Jeffrey J.
Publicado 2022

MHC Class I Immunopeptidome: Past, Present, and Future

por Yewdell, Jonathan W.
Publicado 2022

Crystal structures of N-myristoylated lipopeptide-bound HLA class I complexes indicate reorganization of B-pocket architecture upon ligand binding

por Asa, Minori, Morita, Daisuke, Kuroha, Jin, Mizutani, Tatsuaki, Mori, Naoki, Mikami, Bunzo, Sugita, Masahiko
Publicado 2022

Iron-regulated assembly of the cytosolic iron–sulfur cluster biogenesis machinery

por Fan, Xiaorui, Barshop, William D., Vashisht, Ajay A., Pandey, Vijaya, Leal, Stephanie, Rayatpisheh, Shima, Jami-Alahmadi, Yasaman, Sha, Jihui, Wohlschlegel, James A.
Publicado 2022

Cross-seeding of WT amyloid-β with Arctic but not Italian familial mutants accelerates fibril formation in Alzheimer's disease

por Liang, Ruina, Tian, Yao, Viles, John H.
Publicado 2022

Discovery of a small-molecule inhibitor of the TRIP8b–HCN interaction with efficacy in neurons

por Han, Ye, Iyamu, Iredia D., Clutter, Matthew R., Mishra, Rama K., Lyman, Kyle A., Zhou, Chengwen, Michailidis, Ioannis, Xia, Maya Y., Sharma, Horrick, Luan, Chi-Hao, Schiltz, Gary E., Chetkovich, Dane M.
Publicado 2022

Multifaceted regulation of the sumoylation of the Sgs1 DNA helicase

por Li, Shibai, Mutchler, Ashley, Zhu, Xinji, So, Stephen, Epps, John, Guan, Danying, Zhao, Xiaolan, Xue, Xiaoyu
Publicado 2022

Ingestion of single guide RNAs induces gene overexpression and extends lifespan in Caenorhabditis elegans via CRISPR activation

por Fischer, Fabian, Benner, Christoph, Goyala, Anita, Grigolon, Giovanna, Vitiello, Davide, Wu, JiaYee, Zarse, Kim, Ewald, Collin Y., Ristow, Michael
Publicado 2022

Cardiac ventricular myosin and slow skeletal myosin exhibit dissimilar chemomechanical properties despite bearing the same myosin heavy chain isoform

por Wang, Tianbang, Spahiu, Emrulla, Osten, Jennifer, Behrens, Florentine, Grünhagen, Fabius, Scholz, Tim, Kraft, Theresia, Nayak, Arnab, Amrute-Nayak, Mamta
Publicado 2022

Diverse reaction behaviors of artificial ubiquinones in mitochondrial respiratory complex I

por Uno, Shinpei, Masuya, Takahiro, Zdorevskyi, Oleksii, Ikunishi, Ryo, Shinzawa-Itoh, Kyoko, Lasham, Jonathan, Sharma, Vivek, Murai, Masatoshi, Miyoshi, Hideto
Publicado 2022

mTORC1-independent translation control in mammalian cells by methionine adenosyltransferase 2A and S-adenosylmethionine

por Alam, Mahabub, Shima, Hiroki, Matsuo, Yoshitaka, Long, Nguyen Chi, Matsumoto, Mitsuyo, Ishii, Yusho, Sato, Nichika, Sugiyama, Takato, Nobuta, Risa, Hashimoto, Satoshi, Liu, Liang, Kaneko, Mika K., Kato, Yukinari, Inada, Toshifumi, Igarashi, Kazuhiko
Publicado 2022