A conserved set of mutations for stabilizing soluble envelope protein dimers from dengue and Zika viruses to advance the development of subunit vaccines

por Phan, Thanh T.N., Hvasta, Matthew G., Kudlacek, Stephan T., Thiono, Devina J., Tripathy, Ashutosh, Nicely, Nathan I., de Silva, Aravinda M., Kuhlman, Brian
Publicado 2022

Vibrio splendidus flagellin C binds tropomodulin to induce p38 MAPK-mediated p53-dependent coelomocyte apoptosis in Echinodermata

por Dai, Fa, Guo, Ming, Shao, Yina, Li, Chenghua
Publicado 2022

Glycogen-autophagy: Molecular machinery and cellular mechanisms of glycophagy

por Koutsifeli, Parisa, Varma, Upasna, Daniels, Lorna J., Annandale, Marco, Li, Xun, Neale, Joshua P.H., Hayes, Sarah, Weeks, Kate L., James, Samuel, Delbridge, Lea M.D., Mellor, Kimberley M.
Publicado 2022

Harmonizing Labeling and Analytical Strategies to Obtain Protein Turnover Rates in Intact Adult Animals

por Hammond, Dean E., Simpson, Deborah M., Franco, Catarina, Wright Muelas, Marina, Waters, John, Ludwig, R.W., Prescott, Mark C., Hurst, Jane L., Beynon, Robert J., Lau, Edward
Publicado 2022

TIP60 acts as a regulator of genes involved in filopodia formation and cell migration during wound healing

por Dubey, Shraddha, Jaiswal, Bharti, Gupta, Ashish
Publicado 2022

Withdrawal: Reactive oxygen species (ROS) mediate p300-dependent STAT1 protein interaction with peroxisome proliferator-activated receptor (PPAR)-γ in CD36 protein expression and f...

por Kotla, Sivareddy, Rao, Gadiparthi N.
Publicado 2022

Membrane translocation of folded proteins

por Pei, Dehua, Dalbey, Ross E.
Publicado 2022

Correction: Exostosin glycosyltransferase 1 reduces porcine reproductive and respiratory syndrome virus infection through proteasomal degradation of nsp3 and nsp5

por Zhang, Xiaoxiao, Dong, Wenjuan, Wang, Xun, Zhu, Zhenbang, He, Sheng, Zhang, Hui, Chen, Yaosheng, Liu, Xiaohong, Guo, Chunhe
Publicado 2022

Transcription factor GATA2 may potentiate follicle-stimulating hormone production in mice via induction of the BMP antagonist gremlin in gonadotrope cells

por Schang, Gauthier, Ongaro, Luisina, Brûlé, Emilie, Zhou, Xiang, Wang, Ying, Boehm, Ulrich, Ruf-Zamojski, Frederique, Zamojski, Michel, Mendelev, Natalia, Seenarine, Nitish, Amper, Mary Anne, Nair, Venugopalan, Ge, Yongchao, Sealfon, Stuart C., Bernard, Daniel J.
Publicado 2022

TET2–BCLAF1 transcription repression complex epigenetically regulates the expression of colorectal cancer gene Ascl2 via methylation of its promoter

por Shang, Yangyang, Jiang, Tao, Ran, Lijian, Hu, Wenjing, Wu, Yun, Ye, Jun, Peng, Zhihong, Chen, Lei, Wang, Rongquan
Publicado 2022

Proprotein convertase PCSK9 affects expression of key surface proteins in human pancreatic beta cells via intracellular and extracellular regulatory circuits

por Saitoski, Kevin, Ryaboshapkina, Maria, Hamza, Ghaith M., Jarnuczak, Andrew F., Berthault, Claire, Carlotti, Françoise, Armanet, Mathieu, Sengupta, Kaushik, Underwood, Christina Rye, Andersson, Shalini, Guillas, Isabelle, Le Goff, Wilfried, Scharfmann, Raphael
Publicado 2022

Extended conformational states dominate the Hsp90 chaperone dynamics

por Jussupow, Alexander, Lopez, Abraham, Baumgart, Mona, Mader, Sophie L., Sattler, Michael, Kaila, Ville R.I.
Publicado 2022

Immunopeptidomics: Reading the Immune Signal That Defines Self From Nonself

por Thibault, Pierre, Perreault, Claude
Publicado 2022

Mechanistic insights into accelerated α-synuclein aggregation mediated by human microbiome-associated functional amyloids

por Bhoite, Sujeet S., Han, Yilin, Ruotolo, Brandon T., Chapman, Matthew R.
Publicado 2022

MRG Proteins Are Shared by Multiple Protein Complexes With Distinct Functions

por Devoucoux, Maëva, Roques, Céline, Lachance, Catherine, Lashgari, Anahita, Joly-Beauparlant, Charles, Jacquet, Karine, Alerasool, Nader, Prudente, Alexandre, Taipale, Mikko, Droit, Arnaud, Lambert, Jean-Philippe, Hussein, Samer M.I., Côté, Jacques
Publicado 2022

Critical roles of protein disulfide isomerases in balancing proteostasis in the nervous system

por Medinas, Danilo B., Rozas, Pablo, Hetz, Claudio
Publicado 2022

The Toxoplasma glucan phosphatase TgLaforin utilizes a distinct functional mechanism that can be exploited by therapeutic inhibitors

por Murphy, Robert D., Chen, Tiantian, Lin, Jianping, He, Rongjun, Wu, Li, Pearson, Caden R., Sharma, Savita, Vander Kooi, Carl D., Sinai, Anthony P., Zhang, Zhong-Yin, Vander Kooi, Craig W., Gentry, Matthew S.
Publicado 2022

FOXF2 oppositely regulates stemness in luminal and basal-like breast cancer cells through the Wnt/beta-catenin pathway

por Zhang, Xiao, Zhang, Rui, Hou, Chen, He, Rui, Wang, Qing-Shan, Zhou, Tian-Hao, Li, Xiao-Qing, Zhai, Qiong-Li, Feng, Yu-Mei
Publicado 2022

De(C1P)hering the role of ceramide-1-phosphate levels in skin wound healing

por Agrawal, Rashi, Bollag, Wendy B.
Publicado 2022

Crystal structure of mevalonate 3,5-bisphosphate decarboxylase reveals insight into the evolution of decarboxylases in the mevalonate metabolic pathways

por Aoki, Mizuki, Vinokur, Jeffrey, Motoyama, Kento, Ishikawa, Rino, Collazo, Michael, Cascio, Duilio, Sawaya, Michael R., Ito, Tomokazu, Bowie, James U., Hemmi, Hisashi
Publicado 2022