Expression of GnT-III decreases chemoresistance via negatively regulating P-glycoprotein expression: Involvement of the TNFR2-NF-κB signaling pathway

por Song, Wanli, Liang, Caixia, Sun, Yuhan, Morii, Sayaka, Yomogida, Shin, Isaji, Tomoya, Fukuda, Tomohiko, Hang, Qinglei, Hara, Akiyoshi, Nakano, Miyako, Gu, Jianguo
Publicado 2023

Selective PPARγ modulator diosmin improves insulin sensitivity and promotes browning of white fat

por Yu, Jian, Hu, Yepeng, Sheng, Maozheng, Gao, Mingyuan, Guo, Wenxiu, Zhang, Zhe, Wang, Dongmei, Wu, Xia, Li, Jin, Chen, Yantao, Zhao, Wenjun, Liu, Caizhi, Cui, Xiangdi, Chen, Xin, Zhao, Cheng, Chen, Huang, Xiao, Junjie, Chen, Shijie, Luo, Cheng, Xu, Lingyan, Gu, Xuejiang, Ma, Xinran
Publicado 2023

UHMK1 is a novel splicing regulatory kinase

por Arfelli, Vanessa C., Chang, Yun-Chien, Bagnoli, Johannes W., Kerbs, Paul, Ciamponi, Felipe E., Paz, Laissa M. da S., Pankivskyi, Serhii, de Matha Salone, Jean, Maucuer, Alexandre, Massirer, Katlin B., Enard, Wolfgang, Kuster, Bernhard, Greif, Philipp A., Archangelo, Leticia Fröhlich
Publicado 2023

Molecular dynamics simulations reveal the importance of amyloid-beta oligomer β-sheet edge conformations in membrane permeabilization

por Matthes, Dirk, de Groot, Bert L.
Publicado 2023

Phosphoethanolamine cytidylyltransferase ameliorates mitochondrial function and apoptosis in hepatocytes in T2DM in vitro

por Xu, Hu, Li, Weizu, Huang, Lei, He, Xinyu, Xu, Bei, He, Xueqing, Chen, Wentong, Wang, Yaoxing, Xu, Wenjun, Wang, Sheng, Kong, Qin, Xu, Youzhi, Lu, Wenjie
Publicado 2023

Conservation, abundance, glycosylation profile, and localization of the TSP protein family in Cryptosporidium parvum

por John, Alan, M. Bader, Stefanie, Madiedo Soler, Niccolay, Wiradiputri, Kharizta, Tichkule, Swapnil, Smyth, Sean T., Ralph, Stuart A., Jex, Aaron R., Scott, Nichollas E., Tonkin, Christopher J., Goddard-Borger, Ethan D.
Publicado 2023

The Pseudomonas aeruginosa PAO1 metallo flavoprotein d-2-hydroxyglutarate dehydrogenase requires Zn(2+) for substrate orientation and activation

por Quaye, Joanna A., Gadda, Giovanni
Publicado 2023

Conformational dynamics control assembly of an extremely long bacteriophage tail tube

por Agnello, Emily, Pajak, Joshua, Liu, Xingchen, Kelch, Brian A.
Publicado 2023

ER stress induces upregulation of transcription factor Tbx20 and downstream Bmp2 signaling to promote cardiomyocyte survival

por Das, Shreya, Mondal, Arunima, Dey, Chandrani, Chakraborty, Santanu, Bhowmik, Rudranil, Karmakar, Sanmoy, Sengupta, Arunima
Publicado 2023

Crosstalk between protein kinase C α and transforming growth factor β signaling mediated by Runx2 in intestinal epithelial cells

por Li, Xinyue, Kaur, Navneet, Albahrani, Mustafa, Karpf, Adam R., Black, Adrian R., Black, Jennifer D.
Publicado 2023

The 5-lipoxygenase/cyclooxygenase-2 cross-over metabolite, hemiketal E(2), enhances VEGFR2 activation and promotes angiogenesis

por Nakashima, Fumie, Giménez-Bastida, Juan A., Luis, Paula B., Presley, Sai H., Boer, Robert E., Chiusa, Manuel, Shibata, Takahiro, Sulikowski, Gary A., Pozzi, Ambra, Schneider, Claus
Publicado 2023

Disruption of Ephx2 in cardiomyocytes but not endothelial cells improves functional recovery after ischemia-reperfusion in isolated mouse hearts

por Edin, Matthew L., Gruzdev, Artiom, Bradbury, J. Alyce, Graves, Joan P., Lih, Fred B., DeGraff, Laura M., Fleming, Ingrid, Zeldin, Darryl C.
Publicado 2023

The aryl sulfonamide indisulam inhibits gastric cancer cell migration by promoting the ubiquitination and degradation of the transcription factor ZEB1

por Lu, Jiaqi, Li, Dan, Jiang, Honglv, Li, Yue, Lu, Chengpiao, Chen, Tao, Wang, Yuhong, Wang, Xiaohui, Sun, Wenzhao, Pu, Zhongjian, Qiao, Chunhua, Ma, Jingjing, Xu, Guoqiang
Publicado 2023

The mode of action of tapasin on major histocompatibility class I (MHC-I) molecules

por Lan, By Huan, Becker, Moritz, Freund, Christian
Publicado 2023

s-Afadin binds to MAGUIN/Cnksr2 and regulates the localization of the AMPA receptor and glutamatergic synaptic response in hippocampal neurons

por Maruo, Tomohiko, Mizutani, Kiyohito, Miyata, Muneaki, Kuriu, Toshihiko, Sakakibara, Shotaro, Takahashi, Hatena, Kida, Daichi, Maesaka, Kouki, Sugaya, Tsukiko, Sakane, Ayuko, Sasaki, Takuya, Takai, Yoshimi, Mandai, Kenji
Publicado 2023

The signaling protein GIV/Girdin mediates the Nephrin-dependent insulin secretion of pancreatic islet β cells in response to high glucose

por Wang, Hao, Yuan, Ying-Chao, Chang, Cong, Izumi, Tetsuro, Wang, Hong-Hui, Yang, Jin-Kui
Publicado 2023

Burst kinetics and CNNM binding are evolutionarily conserved properties of phosphatases of regenerating liver

por Fakih, Rayan, Goldstein, Robert H., Kozlov, Guennadi, Gehring, Kalle
Publicado 2023

SET7 methylates the deubiquitinase OTUB1 at Lys (122) to impair its binding to E2 enzyme UBC13 and relieve its suppressive role on ferroptosis

por Deng, Hongyan, Jia, Shuke, Tang, Jinhua, Rong, Fangjing, Xu, Chenxi, Chen, Xiaoyun, Wang, Zixuan, Zhu, Chunchun, Sun, Xueyi, Liao, Qian, Liu, Wen, Li, Wenhua, Xiao, Wuhan, Liu, Xing
Publicado 2023

The function of the phytoplasma effector SWP12 depends on the properties of two key amino acids

por Bai, Bixin, Zhang, Guoding, Pei, Baoyan, Song, Qingting, Hao, Xing’an, Zhao, Lei, Wu, Yunfeng
Publicado 2023

MBOAT7-driven lysophosphatidylinositol acylation in adipocytes contributes to systemic glucose homeostasis

por Massey, William J., Varadharajan, Venkateshwari, Banerjee, Rakhee, Brown, Amanda L., Horak, Anthony J., Hohe, Rachel C., Jung, Bryan M., Qiu, Yunguang, Chan, E. Ricky, Pan, Calvin, Zhang, Renliang, Allende, Daniela S., Willard, Belinda, Cheng, Feixiong, Lusis, Aldons J., Brown, J. Mark
Publicado 2023