Loss of small GTPase Rab7 activation in prion infection negatively affects a feedback loop regulating neuronal cholesterol metabolism

por Cherry, Pearl, Lu, Li, Shim, Su Yeon, Ebacher, Vincent, Tahir, Waqas, Schatzl, Hermann M., Hannaoui, Samia, Gilch, Sabine
Publicado 2023

Comprehensive analysis of RNA-binding protein SRSF2-dependent alternative splicing signature in malignant proliferation of colorectal carcinoma

por Liu, Weizhen, Li, Dongfang, Lu, Ting, Zhang, Haosheng, Chen, Zhengxin, Ruan, Qinli, Zheng, Zihui, Chen, Linlin, Guo, Jun
Publicado 2023

Disruption of the interaction between mutationally activated Gα(q) and Gβγ attenuates aberrant signaling

por Aumiller, Jenna L., Wedegaertner, Philip B.
Publicado 2023

Human apoA-I[Lys107del] mutation affects lipid surface behavior of apoA-I and its ability to form large nascent HDL

por Gorshkova, Irina N., Meyers, Nathan L., Herscovitz, Haya, Mei, Xiaohu, Atkinson, David
Publicado 2022

Role of omega-3 endocannabinoids in the modulation of T-cell activity in a multiple sclerosis experimental autoimmune encephalomyelitis (EAE) model

por Kim, Justin S., Soto-Diaz, Katiria, Bingham, Tanner W., Steelman, Andrew J., Das, Aditi
Publicado 2023

Sterol-regulated transmembrane protein TMEM86a couples LXR signaling to regulation of lysoplasmalogens in macrophages

por van Wouw, Suzanne A.E., van den Berg, Marlene, El Ouraoui, Maroua, Meurs, Amber, Kingma, Jenina, Ottenhoff, Roelof, Loix, Melanie, Hoeksema, Marten A., Prange, Koen, Pasterkamp, Gerard, Hendriks, Jerome J.A., Bogie, Jeroen F.J., van Klinken, Jan B., Vaz, Frederic M., Jongejan, Aldo, de Winther, Menno P.J., Zelcer, Noam
Publicado 2022

HSP70 mediates a crosstalk between the estrogen and the heat shock response pathways

por Silveira, Maruhen Amir Datsch, Khadangi, Fatemeh, Mersaoui, Sofiane Yacine, Naik, Divya, Masson, Jean-Yves, Bilodeau, Steve
Publicado 2023

Structural analysis of the interaction between human cytokine BMP-2 and the antagonist Noggin reveals molecular details of cell chondrogenesis inhibition

por Robert, Charly, Kerff, Frédéric, Bouillenne, Fabrice, Gavage, Maxime, Vandevenne, Marylène, Filée, Patrice, Matagne, André
Publicado 2023

Influenza virus and pneumococcal neuraminidases enhance catalysis by similar yet distinct sialic acid–binding strategies

por Klenow, Laura, Elfageih, Rageia, Gao, Jin, Wan, Hongquan, Withers, Stephen G., de Gier, Jan-Willem, Daniels, Robert
Publicado 2023

ADR3, a next generation i-body to human RANKL, inhibits osteoclast formation and bone resorption

por Qiu, Heng, Hosking, Christopher, Rothzerg, Emel, Samantha, Ariela, Chen, Kai, Kuek, Vincent, Jin, Haiming, Zhu, Sipin, Vrielink, Alice, Lim, Kevin, Foley, Michael, Xu, Jiake
Publicado 2023

Ensembles of human myosin-19 bound to calmodulin and regulatory light chain RLC12B drive multimicron transport

por Pollard, Luther W., Coscia, Stephen M., Rebowski, Grzegorz, Palmer, Nicholas J., Holzbaur, Erika L.F., Dominguez, Roberto, Ostap, E. Michael
Publicado 2023

SPECC1L binds the myosin phosphatase complex MYPT1/PP1β and can regulate its distribution between microtubules and filamentous actin

por Mehta, Virja, Decan, Nathalie, Ooi, Sarah, Gaudreau-Lapierre, Antoine, Copeland, John W., Trinkle-Mulcahy, Laura
Publicado 2023

Exosomes are involved in iron transport from human blood–brain barrier endothelial cells and are modified by endothelial cell iron status

por Palsa, Kondaiah, Baringer, Stephanie L., Shenoy, Ganesh, Spiegelman, Vladimir S., Simpson, Ian A., Connor, James R.
Publicado 2023

High-density lipoproteins mediate small RNA intercellular communication between dendritic cells and macrophages

por Castleberry, Mark, Raby, Chase A., Ifrim, Anca, Shibata, Yasuhiro, Matsushita, Sachi, Ugawa, Shinya, Miura, Yutaka, Hori, Atsushi, Miida, Takashi, Linton, MacRae F., Michell, Danielle L., Tsujita, Maki, Vickers, Kasey C.
Publicado 2023

Apo-metallothionein-3 cooperatively forms tightly compact structures under physiological conditions

por Yuan, Amelia T., Korkola, Natalie C., Stillman, Martin J.
Publicado 2023

The role of glycans in the mechanobiology of cancer

por Purushothaman, Anurag, Mohajeri, Mohammad, Lele, Tanmay P.
Publicado 2023

The 5′UTR of HCoV-OC43 adopts a topologically constrained structure to intrinsically repress translation

por Mackeown, Matthew, Kung, Yu-An, Davila-Calderon, Jesse, Ford, William P., Luo, Le, Henry, Barrington, Li, Mei-Ling, Brewer, Gary, Shih, Shin-Ru, Tolbert, Blanton S.
Publicado 2023

The impact of glucose on mitochondria and life span is determined by the integrity of proline catabolism in Caenorhabditis elegans

por Feng, Xi, Wang, Xinyu, Zhou, Lei, Pang, Shanshan, Tang, Haiqing
Publicado 2023

RanBP9 controls the oligomeric state of CTLH complex assemblies

por van gen Hassend, Pia Maria, Pottikkadavath, Aparna, Delto, Carolyn, Kuhn, Monika, Endres, Michelle, Schönemann, Lars, Schindelin, Hermann
Publicado 2023

Polo-like kinase 1 (PLK1) O-GlcNAcylation is essential for dividing mammalian cells and inhibits uterine carcinoma

por Yan, Sheng, Peng, Bin, Kan, Shifeng, Shao, Guangcan, Xiahou, Zhikai, Tang, Xiangyan, Chen, Yong-Xiang, Dong, Meng-Qiu, Liu, Xiao, Xu, Xingzhi, Li, Jing
Publicado 2023