Simultaneous inhibition of two neutrophil serine proteases by the S. aureus innate immune evasion protein EapH2

por Mishra, Nitin, Herdendorf, Timothy J., Prakash, Om, Geisbrecht, Brian V.
Publicado 2023

Carnitine o-octanoyltransferase is a p53 target that promotes oxidative metabolism and cell survival following nutrient starvation

por Sanford, Jack D., Franklin, Derek, Grois, Gabriella A., Jin, Aiwen, Zhang, Yanping
Publicado 2023

Ubiquitin-like protein 5 is a novel player in the UPR–PERK arm and ER stress–induced cell death

por Wang, Wei, Hawkridge, Adam M., Ma, Yibao, Zhang, Bei, Mangrum, John B., Hassan, Zaneera H., He, Tianhai, Blat, Sofiya, Guo, Chunqing, Zhou, Huiping, Liu, Jinze, Wang, Xiang-Yang, Fang, Xianjun
Publicado 2023

A genome-wide screen reveals that Dyrk1A kinase promotes nucleotide excision repair by preventing aberrant overexpression of cyclin D1 and p21

por Bélanger, François, Roussel, Cassandra, Sawchyn, Christina, St-Hilaire, Edlie, Gezzar-Dandashi, Sari, Kimenyi Ishimwe, Aimé Boris, Mallette, Frédérick Antoine, Wurtele, Hugo, Drobetsky, Elliot
Publicado 2023

Arachidonic acid reverses cholesterol and zinc inhibition of human voltage-gated proton channels

por Han, Shuo, Applewhite, Sarah, DeCata, Jenna, Jones, Samuel, Cummings, John, Wang, Shizhen
Publicado 2023

Mitochondrial folate metabolism–mediated α-linolenic acid exhaustion masks liver fibrosis resolution

por Gao, Yanjie, Zheng, Bingfeng, Xu, Shuaiqi, Zhao, Zhibo, Liu, Wanyue, Wang, Tingyu, Yuan, Manman, Sun, Xueqing, Tan, Yang, Xu, Qiang, Wu, Xingxin
Publicado 2023

O-GalNAc glycosylation determines intracellular trafficking of APP and Aβ production

por Tachida, Yuriko, Iijima, Junko, Takahashi, Kazuto, Suzuki, Hideaki, Kizuka, Yasuhiko, Yamaguchi, Yoshiki, Tanaka, Katsunori, Nakano, Miyako, Takakura, Daisuke, Kawasaki, Nana, Saito, Yuko, Manya, Hiroshi, Endo, Tamao, Kitazume, Shinobu
Publicado 2023

SpotLight Proteomics Identifies Variable Sequences of Blood Antibodies Specific Against Deamidated Human Serum Albumin

por Wang, Jijing, Lundström, Susanna L., Lu, Weiqi, Huang, Yiqi, Rodin, Sergey, Zubarev, Roman A.
Publicado 2023

Identification and characterization of aptameric inhibitors of human neutrophil elastase

por Malicki, Stanisław, Książek, Mirosław, Sochaj Gregorczyk, Alicja, Kamińska, Marta, Golda, Anna, Chruścicka, Barbara, Mizgalska, Danuta, Potempa, Jan, Marti, Hans-Peter, Kozieł, Joanna, Wieczorek, Maciej, Pieczykolan, Jerzy, Mydel, Piotr, Dubin, Grzegorz
Publicado 2023

Diversity of function and higher-order structure within HWE sensor histidine kinases

por Dikiy, Igor, Swingle, Danielle, Toy, Kaitlyn, Edupuganti, Uthama R., Rivera-Cancel, Giomar, Gardner, Kevin H.
Publicado 2023

Differential sensitivity of the yeast Lon protease Pim1p to impaired mitochondrial respiration

por Metzger, Meredith B., Scales, Jessica L., Grant, Garis A., Molnar, Abigail E., Loncarek, Jadranka, Weissman, Allan M.
Publicado 2023

Transgenic mice lacking FGF15/19-SHP phosphorylation display altered bile acids and gut bacteria, promoting nonalcoholic fatty liver disease

por Kim, Young-Chae, Qi, Ming, Dong, Xingchen, Seok, Sunmi, Sun, Hao, Kemper, Byron, Fu, Ting, Kemper, Jongsook Kim
Publicado 2023

Free ferrous ions sustain activity of mammalian stearoyl-CoA desaturase-1

por Shen, Jiemin, Wu, Gang, Pierce, Brad S., Tsai, Ah-Lim, Zhou, Ming
Publicado 2023

Monitoring RNA restructuring in a human cell-free extract reveals eIF4A-dependent and eIF4A-independent unwinding activity

por O'Sullivan, Mattie H., Fraser, Christopher S.
Publicado 2023

Allosteric inhibition of the epidermal growth factor receptor through disruption of transmembrane interactions

por Rybak, Jennifer A., Sahoo, Amita R., Kim, Soyeon, Pyron, Robert J., Pitts, Savannah B., Guleryuz, Saffet, Smith, Adam W., Buck, Matthias, Barrera, Francisco N.
Publicado 2023

Disruption of Golgi markers by two RILP-directed shRNAs in neurons: A new role for RILP or a neuron-specific off-target phenotype?

por Yap, Chan Choo, Digilio, Laura, McMahon, Lloyd, Winckler, Bettina
Publicado 2023

In-Depth Characterization of Apoptosis N-Terminome Reveals a Link Between Caspase-3 Cleavage and Posttranslational N-Terminal Acetylation

por Hanna, Rawad, Rozenberg, Andrey, Saied, Layla, Ben-Yosef, Daniel, Lavy, Tali, Kleifeld, Oded
Publicado 2023

Phosphorylation of USP20 on Ser334 by IRAK1 promotes IL-1β-evoked signaling in vascular smooth muscle cells and vascular inflammation

por Zhang, Lisheng, Wu, Jiao-Hui, Jean-Charles, Pierre-Yves, Murali, Pavitra, Zhang, Wenli, Jazic, Aeva, Kaur, Suneet, Nepliouev, Igor, Stiber, Jonathan A., Snow, Kamie, Freedman, Neil J., Shenoy, Sudha K.
Publicado 2023

PE-STOP: A versatile tool for installing nonsense substitutions amenable for precise reversion

por Song, Ziguo, Zhang, Guiquan, Huang, Shuhong, Liu, Yao, Li, Guanglei, Zhou, Xianhui, Sun, Jiayuan, Gao, Pengfei, Chen, Yulin, Huang, Xingxu, Liu, Jianghuai, Wang, Xiaolong
Publicado 2023

The Pros of changing tRNA identity

por Ibba, Michael
Publicado 2023