Deubiquitinase USP2 stabilizes the MRE11–RAD50–NBS1 complex at DNA double-strand break sites by counteracting the ubiquitination of NBS1

por Kim, Hyunsup, Kim, Dongmin, Choi, Hyemin, Shin, Gwangsu, Lee, Joon-Kyu
Publicado 2022

Glucose transporter GLUT1 expression is important for oriental river prawn (Macrobrachium nipponense) hemocyte adaptation to hypoxic conditions

por Sun, Xichao, Xue, Cheng, Jin, Yiting, Bian, Chao, Zhou, Na, Sun, Shengming
Publicado 2022

Systematic pharmacological analysis of agonistic and antagonistic fibroblast growth factor receptor 1 MAbs reveals a similar unique mode of action

por Chan, Jocelyn, Chan, Joyce, Shao, Lily, Stawicki, Scott S., Pham, Victoria C., Akita, Rob W., Hafner, Marc, Crocker, Lisa, Yu, Kebing, Koerber, James T., Schaefer, Gabriele, Comps-Agrar, Laetitia
Publicado 2022

Multiple Layers of Complexity in O-Glycosylation Illustrated With the Urinary Glycoproteome

por Pap, Adam, Kiraly, Istvan Elod, Medzihradszky, Katalin F., Darula, Zsuzsanna
Publicado 2022

Plasma S1P and Sphingosine are not Different Prior to Pre-Eclampsia in Women at High Risk of Developing the Disease

por Johnstone, Edward D., Westwood, Melissa, Dilworth, Mark, Wray, Jonathan R., Kendall, Alexandra C., Nicolaou, Anna, Myers, Jenny E.
Publicado 2022

Rosiglitazone Reverses Inflammation in Epididymal White Adipose Tissue in Hormone-Sensitive Lipase-Knockout Mice

por Kotzbeck, Petra, Taschler, Ulrike, Haudum, Christoph, Foessl, Ines, Schoiswohl, Gabriele, Boulgaropoulos, Beate, Bounab, Kaddour, Einsiedler, Johanna, Pajed, Laura, Tilp, Anna, Schwarz, Anna, Eichmann, Thomas O., Obermayer-Pietsch, Barbara, Giordano, Antonio, Cinti, Saverio, Zechner, Rudolf, Pieber, Thomas R.
Publicado 2022

Toll-like receptor 4 and lipopolysaccharide from commensal microbes regulate Tembusu virus infection

por Wu, Zhen, Hu, Tao, Merits, Andres, He, Yu, Wang, Mingshu, Jia, Renyong, Zhu, Dekang, Liu, Mafeng, Zhao, Xinxin, Yang, Qiao, Wu, Ying, Zhang, Shaqiu, Huang, Juan, Mao, Sai, Ou, Xumin, Gao, Qun, Sun, Di, Liu, Yunya, Zhang, Ling, Yu, Yanling, Cheng, Anchun, Chen, Shun
Publicado 2022

Lysyl hydroxylase 3–mediated post-translational modifications are required for proper biosynthesis of collagen α1α1α2(IV)

por Ishikawa, Yoshihiro, Taga, Yuki, Coste, Thibault, Tufa, Sara F., Keene, Douglas R., Mizuno, Kazunori, Tournier-Lasserve, Elisabeth, Gould, Douglas B.
Publicado 2022

Programmed death ligand 1 intracellular interactions with STAT3 and focal adhesion protein Paxillin facilitate lymphatic endothelial cell remodeling

por Schafer, Johnathon B., Lucas, Erin D., Dzieciatkowska, Monika, Forward, Tadg, Tamburini, Beth A. Jirón
Publicado 2022

A mass spectrometry imaging and lipidomic investigation reveals aberrant lipid metabolism in the orthotopic mouse glioma

por Wang, Hay-Yan J., Huang, Chiung-Yin, Wei, Kuo-Chen, Hung, Kuo-Chen
Publicado 2022

rAAV-CRISPRa therapy corrects Rai1 haploinsufficiency and rescues selective disease features in Smith-Magenis syndrome mice

por Chang, Hao-Cheng, Lee, Yu-Ju, Javed, Sehrish, Haque, Minza, Chang, Ya-Ting, Lin, Yu Cheng, Oram, Cameron, Huang, Wei-Hsiang
Publicado 2022

On the illusion of auxotrophy: met15Δ yeast cells can grow on inorganic sulfur, thanks to the previously uncharacterized homocysteine synthase Yll058w

por Van Oss, S. Branden, Parikh, Saurin Bipin, Castilho Coelho, Nelson, Wacholder, Aaron, Belashov, Ivan, Zdancewicz, Sara, Michaca, Manuel, Xu, Jiazhen, Kang, Yun Pyo, Ward, Nathan P., Yoon, Sang Jun, McCourt, Katherine M., McKee, Jake, Ideker, Trey, VanDemark, Andrew P., DeNicola, Gina M., Carvunis, Anne-Ruxandra
Publicado 2022

A new nanobody-enzyme fusion protein–linked immunoassay for detecting antibodies against influenza A virus in different species

por Ji, Pinpin, Wang, Kun, Zhang, Lu, Yan, Zhenda, Kong, Min, Sun, Xuwen, Zhang, Qiang, Zhou, Ning, Liu, Baoyuan, Zhou, En-Min, Sun, Yani, Wang, Xinjie, Zhao, Qin
Publicado 2022

Mutations in the α4-α5 allosteric lobe of RAS do not significantly impair RAS signaling or self-association

por Whaby, Michael, Wallon, Lauren, Mazzei, Megan, Khan, Imran, Teng, Kai Wen, Koide, Shohei, O’Bryan, John P.
Publicado 2022

Cartwheel disassembly regulated by CDK1-cyclin B kinase allows human centriole disengagement and licensing

por Huang, Fan, Xu, Xiaowei, Xin, Guangwei, Zhang, Boyan, Jiang, Qing, Zhang, Chuanmao
Publicado 2022

Genome-wide metabolite quantitative trait loci analysis (mQTL) in red blood cells from volunteer blood donors

por Moore, Amy, Busch, Michael P., Dziewulska, Karolina, Francis, Richard O., Hod, Eldad A., Zimring, James C., D’Alessandro, Angelo, Page, Grier P.
Publicado 2022

Transmembrane anterior posterior transformation 1 regulates BMP signaling and modulates the protein stability of SMAD1/5

por Wang, Bo, Zhao, Qian, Gong, Xiaoxia, Wang, Caixia, Bai, Yan, Wang, Hongying, Zhou, Jianfeng, Rong, Xiaozhi
Publicado 2022

The leucine-rich repeat (LRR) domain of NLRP3 is required for NLRP3 inflammasome activation in macrophages

por Duan, Yanhui, Wang, Jihong, Cai, Juan, Kelley, Nathan, He, Yuan
Publicado 2022

Role of the membrane anchor in the regulation of Lck activity

por Porciello, Nicla, Cipria, Deborah, Masi, Giulia, Lanz, Anna-Lisa, Milanetti, Edoardo, Grottesi, Alessandro, Howie, Duncan, Cobbold, Steve P., Schermelleh, Lothar, He, Hai-Tao, D’Abramo, Marco, Destainville, Nicolas, Acuto, Oreste, Nika, Konstantina
Publicado 2022

The interaction between E3 ubiquitin ligase Parkin and mitophagy receptor PHB2 links inner mitochondrial membrane ubiquitination to efficient mitophagy

por Sun, Shan, Hou, Hongyu, Ma, Guoqiang, Ma, Qilian, Li, Ningning, Zhang, Li, Dong, Chunsheng, Cao, Mian, Tam, Kin Yip, Ying, Zheng, Wang, Hongfeng
Publicado 2022