The SCF–FBXW7 E3 ubiquitin ligase triggers degradation of histone 3 lysine 4 methyltransferase complex component WDR5 to prevent mitotic slippage

por Hänle-Kreidler, Simon, Richter, Kai T., Hoffmann, Ingrid
Publicado 2022

Quantitative affinity measurement of small molecule ligand binding to major histocompatibility complex class-I–related protein 1 MR1

por Wang, Carl J.H., Awad, Wael, Liu, Ligong, Mak, Jeffrey Y.W., Veerapen, Natacha, Illing, Patricia T., Purcell, Anthony W., Eckle, Sidonia B.G., McCluskey, James, Besra, Gurdyal S., Fairlie, David P., Rossjohn, Jamie, Le Nours, Jérôme
Publicado 2022

Loss of transcription factor EB dysregulates the G1/S transition and DNA replication in mammary epithelial cells

por Slade, Logan, Biswas, Dipsikha, Kienesberger, Petra C., Pulinilkunnil, Thomas
Publicado 2022

Half-calcified calmodulin promotes basal activity and inactivation of the L-type calcium channel Ca(V)1.2

por Bartels, Peter, Salveson, Ian, Coleman, Andrea M., Anderson, David E., Jeng, Grace, Estrada-Tobar, Zoila M., Man, Kwun Nok Mimi, Yu, Qinhong, Kuzmenkina, Elza, Nieves-Cintron, Madeline, Navedo, Manuel F., Horne, Mary C., Hell, Johannes W., Ames, James B.
Publicado 2022

Proximity Labeling Facilitates Defining the Proteome Neighborhood of Photosystem II Oxygen Evolution Complex in a Model Cyanobacterium

por Xiao, Zhen, Huang, Chengcheng, Ge, Haitao, Wang, Yan, Duan, Xiaoxiao, Wang, Gaojie, Zheng, Limin, Dong, Jinghui, Huang, Xiahe, Zhang, Yuanya, An, Hongyu, Xu, Wu, Wang, Yingchun
Publicado 2022

Might nontransferrin-bound iron in blood plasma and sera be a nonproteinaceous high-molecular-mass Fe(III) aggregate?

por Vali, Shaik Waseem, Lindahl, Paul A.
Publicado 2022

Grim-19 plays a key role in mitochondrial steroidogenic acute regulatory protein stability and ligand-binding properties in Leydig cells

por Qu, Hu, He, Ke, Zou, Zi-hao, Niu, Gang, Lu, Li, Yao, Bing, Zhong, Wen-wen, Wang, De-juan, Li, Wei
Publicado 2022

Rate of transcription elongation and sequence-specific pausing by RNA polymerase I directly influence rRNA processing

por Huffines, Abigail K., Engel, Krysta L., French, Sarah L., Zhang, Yinfeng, Viktorovskaya, Olga V., Schneider, David A.
Publicado 2022

Products of the visual cycle are detected in mice lacking retinol binding protein 4, the only known vitamin A carrier in plasma

por Montenegro, Diego, Zhao, Jin, Kim, Hye Jin, Shmarakov, Igor O., Blaner, William S., Sparrow, Janet R.
Publicado 2022

Brain-derived neurotrophic factor stimulates the retrograde pathway for axonal autophagy

por Sidibe, David Kader, Kulkarni, Vineet Vinay, Dong, Audrey, Herr, Jessica Brandt, Vogel, Maria Chalokh, Stempel, Max Henry, Maday, Sandra
Publicado 2022

Diptoindonesin G is a middle domain HSP90 modulator for cancer treatment

por Donahue, Kristine, Xie, Haibo, Li, Miyang, Gao, Ang, Ma, Min, Wang, Yidan, Tipton, Rose, Semanik, Nicole, Primeau, Tina, Li, Shunqiang, Li, Lingjun, Tang, Weiping, Xu, Wei
Publicado 2022

SOX9 and TCF transcription factors associate to mediate Wnt/β-catenin target gene activation in colorectal cancer

por Ramakrishnan, Aravinda-Bharathi, Burby, Peter E., Adiga, Kavya, Cadigan, Ken M.
Publicado 2022

Acetyl-CoA carboxylase 1 depletion suppresses de novo fatty acid synthesis and mitochondrial β-oxidation in castration-resistant prostate cancer cells

por Liu, Shaoyou, Lai, Jiarun, Feng, Yuanfa, Zhuo, Yangjia, Zhang, Hui, Chen, Yupeng, Li, Jinchuang, Mei, Xinyue, Zeng, Yanting, Su, Jiaming, Deng, Yulin, Jiang, Funeng, Yang, Shengbang, Tan, Huijing, Hon, Chi Tin, Wei, Sun, Han, Zhaodong, Wang, Fen, Zhong, Weide
Publicado 2022

Specificity of a β-porphyranase produced by the carrageenophyte red alga Chondrus crispus and implications of this unexpected activity on red algal biology

por Manat, Guillaume, Fanuel, Mathieu, Jouanneau, Diane, Jam, Murielle, Mac-Bear, Jessica, Rogniaux, Hélène, Mora, Théo, Larocque, Robert, Lipinska, Agnieszka, Czjzek, Mirjam, Ropartz, David, Ficko-Blean, Elizabeth
Publicado 2022

A cell-based bioluminescence reporter assay of human Sonic Hedgehog protein autoprocessing to identify inhibitors and activators

por Ciulla, Daniel A., Dranchak, Patricia, Pezzullo, John L., Mancusi, Rebecca A., Psaras, Alexandra Maria, Rai, Ganesha, Giner, José-Luis, Inglese, James, Callahan, Brian P.
Publicado 2022

Regulatory role of endoplasmic reticulum resident chaperone protein ERp29 in anti-murine β-coronavirus host cell response

por Bose, Abhishek, Kasle, Grishma, Jana, Rishika, Maulik, Mahua, Thomas, Deepthi, Mulchandani, Vaishali, Mukherjee, Priyanka, Koval, Michael, Das Sarma, Jayasri
Publicado 2022

N6-methyladenosine (m6A) RNA methylation mediated by methyltransferase complex subunit WTAP regulates amelogenesis

por Xie, Furong, Zhu, Xueqin, Liu, Xiao, Chen, Hui, Wang, Jun
Publicado 2022

A penetratin-derived peptide reduces the membrane permeabilization and cell toxicity of α-synuclein oligomers

por Pirhaghi, Mitra, Frank, Signe Andrea, Alam, Parvez, Nielsen, Janni, Sereikaite, Vita, Gupta, Arpit, Strømgaard, Kristian, Andreasen, Maria, Sharma, Deepak, Saboury, Ali Akbar, Otzen, Daniel Erik
Publicado 2022

The bacteriophage lambda integrase catalytic domain can be modified to act with the regulatory domain as a recombination-competent binary recombinase

por Williams, Joe D., Voziyanova, Eugenia, Voziyanov, Yuri
Publicado 2022

Yeast 9-1-1 complex acts as a sliding clamp for DNA synthesis by DNA polymerase ε

por Acharya, Narottam, Prakash, Louise, Prakash, Satya
Publicado 2022