Biphasic transcriptional and posttranscriptional regulation of MYB by androgen signaling mediates its growth control in prostate cancer

por Acharya, Srijan, Anand, Shashi, Khan, Mohammad Aslam, Zubair, Haseeb, Srivastava, Sanjeev Kumar, Singh, Seema, Singh, Ajay Pratap
Publicado 2022

Impact of inherent biases built into proteomic techniques: Proximity labeling and affinity capture compared

por Moreira, Claudia Maria do Nascimento, Kelemen, Cristina D., Obado, Samson O., Zahedifard, Farnaz, Zhang, Ning, Holetz, Fabiola B., Gauglitz, Laura, Dallagiovanna, Bruno, Field, Mark C., Kramer, Susanne, Zoltner, Martin
Publicado 2022

SKAP2 Modular Organization Differently Recognizes SRC Kinases Depending on Their Activation Status and Localization

por Levillayer, Laurine, Cassonnet, Patricia, Declercq, Marion, Santos, Mélanie Dos, Lebreton, Louis, Danezi, Katerina, Demeret, Caroline, Sakuntabhai, Anavaj, Jacob, Yves, Bureau, Jean-François
Publicado 2022

Mass Spectrometry–Based Proteomics Analysis of Human Substantia Nigra From Parkinson's Disease Patients Identifies Multiple Pathways Potentially Involved in the Disease

por Jang, Yura, Pletnikova, Olga, Troncoso, Juan C., Pantelyat, Alexander Y., Dawson, Ted M., Rosenthal, Liana S., Na, Chan Hyun
Publicado 2022

Direct Proteomic Detection and Prioritization of 19 Onchocerciasis Biomarker Candidates in Humans

por Rosa, Bruce A., Curtis, Kurt, Erdmann Gilmore, Petra, Martin, John, Zhang, Qiang, Sprung, Robert, Weil, Gary J., Townsend, R. Reid, Fischer, Peter U., Mitreva, Makedonka
Publicado 2022

A comparative Proteomics Analysis Identified Differentially Expressed Proteins in Pancreatic Cancer–Associated Stellate Cell Small Extracellular Vesicles

por Sarcar, Bhaswati, Fang, Bin, Izumi, Victoria, O. Nunez Lopez, Yury, Tassielli, Alexandra, Pratley, Richard, Jeong, Daniel, Permuth, Jennifer B., Koomen, John M., Fleming, Jason B., Stewart, Paul A.
Publicado 2022

Biosynthesis of prostaglandin 15dPGJ(2) -glutathione and 15dPGJ(2)-cysteine conjugates in macrophages and mast cells via MGST3

por Steinmetz-Späh, Julia, Liu, Jianyang, Singh, Rajkumar, Ekoff, Maria, Boddul, Sanjaykumar, Tang, Xiao, Bergqvist, Filip, Idborg, Helena, Heitel, Pascal, Rönnberg, Elin, Merk, Daniel, Wermeling, Fredrik, Haeggström, Jesper Z., Nilsson, Gunnar, Steinhilber, Dieter, Larsson, Karin, Korotkova, Marina, Jakobsson, Per-Johan
Publicado 2022

Hydroxylation site–specific and production-dependent effects of endogenous oxysterols on cholesterol homeostasis: Implications for SREBP-2 and LXR

por Saito, Hodaka, Tachiura, Wakana, Nishimura, Mizuki, Shimizu, Makoto, Sato, Ryuichiro, Yamauchi, Yoshio
Publicado 2022

Lack of ApoE inhibits ADan amyloidosis in a mouse model of familial Danish dementia

por Fernandez, Anllely, Gomez, Maria-Teresa, Vidal, Ruben
Publicado 2022

NUDT7 regulates total hepatic CoA levels and the composition of the intestinal bile acid pool in male mice fed a Western diet

por Vickers, Schuyler D., Shumar, Stephanie A., Saporito, Dominique C., Kunovac, Amina, Hathaway, Quincy A., Mintmier, Breeanna, King, Judy A., King, Rachel D., Rajendran, Vazhaikkurichi M., Infante, Aniello M., Hollander, John M., Leonardi, Roberta
Publicado 2022

Bioorthogonal azido-S1P works as substrate for S1PR1

por Sternstein, Christine, Schlegel, Jan, Sauer, Markus, Seibel, Jürgen
Publicado 2022

Obtaining the necessary molybdenum cofactor for sulfite oxidase activity in the nematode Caenorhabditis elegans surprisingly involves a dietary source

por Oliphant, Kevin D., Fettig, Robin R., Snoozy, Jennifer, Mendel, Ralf R., Warnhoff, Kurt
Publicado 2022

Negative cooperativity underlies dynamic assembly of the Par complex regulators Cdc42 and Par-3

por Vargas, Elizabeth, Prehoda, Kenneth E.
Publicado 2022

A tumor microenvironment-activated metal-organic framework–based nanoplatform for amplified oxidative stress–induced enhanced chemotherapy

por Li, Bo, Yao, Xin, Li, Jiaqi, Lu, Xin, Zhang, Wen, Duan, Wenyao, Tian, Yupeng, Li, Dandan
Publicado 2022

Ribosomal protein RPL11 haploinsufficiency causes anemia in mice via activation of the RP-MDM2-p53 pathway

por Franklin, Derek A., Liu, Shijie, Jin, Aiwen, Cui, Pengfei, Guo, Zengli, Arend, Kyle C., Moorman, Nathaniel J., He, Shenghui, Wang, Gang Greg, Wan, Yisong Y., Zhang, Yanping
Publicado 2022

Dalcetrapib and anacetrapib increase apolipoprotein E-containing HDL in rabbits and humans

por Brodeur, Mathieu R., Rhainds, David, Charpentier, Daniel, Boulé, Marie, Mihalache-Avram, Téodora, Mecteau, Mélanie, Brand, Geneviève, Pedneault-Gagnon, Valérie, Fortier, Annik, Niesor, Eric J., Rhéaume, Eric, Maugeais, Cyrille, Tardif, Jean-Claude
Publicado 2022

Neutron crystallography and quantum chemical analysis of bilin reductase PcyA mutants reveal substrate and catalytic residue protonation states

por Joutsuka, Tatsuya, Nanasawa, Ryota, Igarashi, Keisuke, Horie, Kazuki, Sugishima, Masakazu, Hagiwara, Yoshinori, Wada, Kei, Fukuyama, Keiichi, Yano, Naomine, Mori, Seiji, Ostermann, Andreas, Kusaka, Katsuhiro, Unno, Masaki
Publicado 2022

Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles

por Lee, Lindsey A., Barrick, Samantha K., Meller, Artur, Walklate, Jonathan, Lotthammer, Jeffrey M., Tay, Jian Wei, Stump, W. Tom, Bowman, Gregory, Geeves, Michael A., Greenberg, Michael J., Leinwand, Leslie A.
Publicado 2022

A peptide derived from adaptor protein STAP-2 inhibits tumor progression by downregulating epidermal growth factor receptor signaling

por Maemoto, Taiga, Kitai, Yuichi, Takahashi, Runa, Shoji, Haruka, Yamada, Shunsuke, Takei, Shiho, Ito, Daiki, Muromoto, Ryuta, Kashiwakura, Jun-ichi, Handa, Haruka, Hashimoto, Ari, Hashimoto, Shigeru, Ose, Toyoyuki, Oritani, Kenji, Matsuda, Tadashi
Publicado 2022

S-acylation of Sprouty and SPRED proteins by the S-acyltransferase zDHHC17 involves a novel mode of enzyme–substrate interaction

por Butler, Liam, Locatelli, Carolina, Allagioti, Despoina, Lousa, Irina, Lemonidis, Kimon, Tomkinson, Nicholas C.O., Salaun, Christine, Chamberlain, Luke H.
Publicado 2022