Targeted Proteomic Quantitation of NRF2 Signaling and Predictive Biomarkers in HNSCC

por Wamsley, Nathan T., Wilkerson, Emily M., Guan, Li, LaPak, Kyle M., Schrank, Travis P., Holmes, Brittany J., Sprung, Robert W., Gilmore, Petra Erdmann, Gerndt, Sophie P., Jackson, Ryan S., Paniello, Randal C., Pipkorn, Patrik, Puram, Sidharth V., Rich, Jason T., Townsend, Reid R., Zevallos, José P., Zolkind, Paul, Le, Quynh-Thu, Goldfarb, Dennis, Major, Michael B.
Publicado 2023

Phenotypic analysis with trans-recombination–based genetic mosaic models

por Zhang, Yu, Zeng, Jianhao, Xu, Bing
Publicado 2023

Hybrid insulin peptide isomers spontaneously form in pancreatic beta-cells from an aspartic anhydride intermediate

por Crawford, Samantha A., Groegler, Jason, Dang, Mylinh, Michel, Cole, Powell, Roger L., Hohenstein, Anita C., Reyes, Kaitlin, Haskins, Kathryn, Wiles, Timothy A., Delong, Thomas
Publicado 2023

CaaX-motif-adjacent residues influence G protein gamma (Gγ) prenylation under suboptimal conditions

por Tennakoon, Mithila, Thotamune, Waruna, Payton, John L., Karunarathne, Ajith
Publicado 2023

The kinesin-14 family motor protein KIFC2 promotes prostate cancer progression by regulating p65

por Liu, Xinyu, Lin, Yu, Long, Weibing, Yi, Renzheng, Zhang, Xiongfeng, Xie, Chaoqun, Jin, Na, Qiu, Ziran, Liu, Xiaobing
Publicado 2023

Co-folding and RNA activation of poliovirus 3C(pro) polyprotein precursors

por Campagnola, Grace, Peersen, Olve
Publicado 2023

Mechanistic characterization of disulfide bond reduction of an ERAD substrate mediated by cooperation between ERdj5 and BiP

por Cai, Xiaohan, Ito, Shogo, Noi, Kentaro, Inoue, Michio, Ushioda, Ryo, Kato, Yukinari, Nagata, Kazuhiro, Inaba, Kenji
Publicado 2023

An essential signaling function of cytoplasmic NELFB is independent of RNA polymerase II pausing

por Pan, Haihui, Cheng, Xiaolong, Rodríguez, Pedro Felipe Gardeazábal, Zhang, Xiaowen, Chung, Inhee, Jin, Victor X., Li, Wei, Hu, Yanfen, Li, Rong
Publicado 2023

The nexus between reactive oxygen species and the mechanism of action of herbicides

por Traxler, Catherine, Gaines, Todd A., Küpper, Anita, Luemmen, Peter, Dayan, Franck E.
Publicado 2023

Methods to Discover and Validate Biofluid-Based Biomarkers in Neurodegenerative Dementias

por Teunissen, Charlotte E., Kimble, Leighann, Bayoumy, Sherif, Bolsewig, Katharina, Burtscher, Felicia, Coppens, Salomé, Das, Shreyasee, Gogishvili, Dea, Fernandes Gomes, Bárbara, Gómez de San José, Nerea, Mavrina, Ekaterina, Meda, Francisco J., Mohaupt, Pablo, Mravinacová, Sára, Waury, Katharina, Wojdała, Anna Lidia, Abeln, Sanne, Chiasserini, Davide, Hirtz, Christophe, Gaetani, Lorenzo, Vermunt, Lisa, Bellomo, Giovanni, Halbgebauer, Steffen, Lehmann, Sylvain, Månberg, Anna, Nilsson, Peter, Otto, Markus, Vanmechelen, Eugeen, Verberk, Inge M.W., Willemse, Eline, Zetterberg, Henrik
Publicado 2023

STPP-UP: An alternative method for drug target identification using protein thermal stability

por Zijlmans, Dick W., Hernández-Quiles, Miguel, Jansen, Pascal W.T.C., Becher, Isabelle, Stein, Frank, Savitski, Mikhail M., Vermeulen, Michiel
Publicado 2023

Protein interaction network analysis of mTOR signaling reveals modular organization

por Wehle, Devin T., Bass, Carter S., Sulc, Josef, Mirzaa, Ghayda, Smith, Stephen E.P.
Publicado 2023

Crystallographic cyanide-probing for cytochrome c oxidase reveals structural bases suggesting that a putative proton transfer H-pathway pumps protons

por Shimada, Atsuhiro, Baba, Jumpei, Nagao, Shuhei, Shinzawa-Itoh, Kyoko, Yamashita, Eiki, Muramoto, Kazumasa, Tsukihara, Tomitake, Yoshikawa, Shinya
Publicado 2023

The effect of linker conformation on performance and stability of a two-domain lytic polysaccharide monooxygenase

por Forsberg, Zarah, Stepnov, Anton A., Tesei, Giulio, Wang, Yong, Buchinger, Edith, Kristiansen, Sandra K., Aachmann, Finn L., Arleth, Lise, Eijsink, Vincent G.H., Lindorff-Larsen, Kresten, Courtade, Gaston
Publicado 2023

Structural insights into Rad18 targeting by the SLF1 BRCT domains

por Huang, Wei, Qiu, Fangjie, Zheng, Lin, Shi, Meng, Shen, Miaomiao, Zhao, Xiaolan, Xiang, Song
Publicado 2023

The long noncoding RNA lnc-H19 is important for endurance exercise by maintaining slow muscle fiber types

por Yue, Yongqi, Yue, Yanru, Fan, Zeyu, Meng, Yingying, Wen, Chenglong, An, Yalong, Yao, Ying, Li, Xiao
Publicado 2023

Comparative analysis of the physical properties of murine and human S100A7: Insight into why zinc piracy is mediated by human but not murine S100A7

por Harrison, Simone A., Naretto, Anais, Balakrishnan, Swati, Perera, Yasiru R., Chazin, Walter J.
Publicado 2023

Elongation rate of RNA polymerase II affects pausing patterns across 3′ UTRs

por Khitun, Alexandra, Brion, Christian, Moqtaderi, Zarmik, Geisberg, Joseph V., Churchman, L. Stirling, Struhl, Kevin
Publicado 2023

Diversity in connexin biology

por Lucaciu, Sergiu A., Leighton, Stephanie E., Hauser, Alexandra, Yee, Ryan, Laird, Dale W.
Publicado 2023

SUMOylation indirectly suppresses activity of the HIF-1α pathway in intestinal epithelial cells

por Malkov, Mykyta I., Flood, Darragh, Taylor, Cormac T.
Publicado 2023