4EBP2-regulated protein translation has a critical role in high-fat diet–induced insulin resistance in hepatocytes

por Han, Xiao, Yang, Fei, Zhang, Zhengyi, Hou, Zhanwu, Sun, Qiong, Su, Tian, Lv, Weiqiang, Wang, Zhen, Yuan, Chao, Zhang, Guanfei, Pi, Xin, Long, Jiangang, Liu, Huadong
Publicado 2023

The C-terminal domain of the antiamyloid chaperone DNAJB6 binds to amyloid-β peptide fibrils and inhibits secondary nucleation

por Österlund, Nicklas, Frankel, Rebecca, Carlsson, Andreas, Thacker, Dev, Karlsson, Maja, Matus, Vanessa, Gräslund, Astrid, Emanuelsson, Cecilia, Linse, Sara
Publicado 2023

Dysregulation of the progranulin-driven autophagy-lysosomal pathway mediates secretion of the nuclear protein TDP-43

por Tanaka, Yoshinori, Ito, Shun-ichi, Honma, Yuki, Hasegawa, Masato, Kametani, Fuyuki, Suzuki, Genjiro, Kozuma, Lina, Takeya, Kosuke, Eto, Masumi
Publicado 2023

Sequence tolerance of immunoglobulin variable domain framework regions to noncanonical intradomain disulfide linkages

por Kim, Dae Young, Kandalaft, Hiba, Lowden, Michael J., Yang, Qingling, Rossotti, Martin A., Robotham, Anna, Kelly, John F., Hussack, Greg, Schrag, Joseph D., Henry, Kevin A., Tanha, Jamshid
Publicado 2023

Outer membrane protein 25 of Brucella suppresses TLR-mediated expression of proinflammatory cytokines through degradation of TLRs and adaptor proteins

por Murugan, Subathra, Nandi, Binita Roy, Mazumdar, Varadendra, Joshi, Kiranmai, Nandini, Prachita, Namani, Swapna, Jakka, Padmaja, Radhakrishnan, Girish K.
Publicado 2023

Uterine Fluid Extracellular Vesicles Proteome Is Altered During the Estrous Cycle

por Piibor, Johanna, Waldmann, Andres, Dissanayake, Keerthie, Andronowska, Aneta, Ivask, Marilin, Prasadani, Madhusha, Kavak, Ants, Kodithuwakku, Suranga, Fazeli, Alireza
Publicado 2023

Structural insights of the p97/VCP AAA+ ATPase: How adapter interactions coordinate diverse cellular functionality

por Braxton, Julian R., Southworth, Daniel R.
Publicado 2023

The structure of NAD(+) consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations

por Klontz, Erik, Obi, Juliet O., Wang, Yajing, Glendening, Gabrielle, Carr, Jahid, Tsibouris, Constantine, Buddula, Sahthi, Nallar, Shreeram, Soares, Alexei S., Beckett, Dorothy, Redzic, Jasmina S., Eisenmesser, Elan, Palm, Cheyenne, Schmidt, Katrina, Scudder, Alexis H., Obiorah, Trinity, Essuman, Kow, Milbrandt, Jeffrey, Diantonio, Aaron, Ray, Krishanu, Snyder, Michelle L.D., Deredge, Daniel, Snyder, Greg A.
Publicado 2023

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

por Kiss, Robert S., Chicoine, Jarred, Khalil, Youssef, Sladek, Robert, Chen, He, Pisaturo, Alessandro, Martin, Cyril, Dale, Jessica D., Brudenell, Tegan A., Kamath, Archith, Kyei-Boahen, Jeffrey, Hafiane, Anouar, Daliah, Girija, Alecki, Célia, Hopes, Tayah S., Heier, Martin, Aligianis, Irene A., Lebrun, Jean-Jacques, Aspden, Julie, Paci, Emanuele, Kerksiek, Anja, Lütjohann, Dieter, Clayton, Peter, Wills, Jimi C., von Kriegsheim, Alex, Nilsson, Tommy, Sheridan, Eamonn, Handley, Mark T.
Publicado 2023

A conserved, noncanonical insert in FIS1 mediates TBC1D15 and DRP1 recruitment for mitochondrial fission

por Ihenacho, Ugochukwu K., Toro, Rafael, Mansour, Rana H., Hill, R. Blake
Publicado 2023

Selective targeting and clustering of phosphatidylserine lipids by RSV M protein is critical for virus particle production

por Swain, Jitendriya, Bierre, Maxime, Veyrié, Laura, Richard, Charles-Adrien, Eleouet, Jean-Francois, Muriaux, Delphine, Bajorek, Monika
Publicado 2023

“Affimer” synthetic protein scaffolds block oxidized LDL binding to the LOX-1 scavenger receptor and inhibit ERK1/2 activation

por Roper, Barnaby W.R., Tiede, Christian, Abdul-Zani, Izma, Cuthbert, Gary A., Jade, Dhananjay, Al-Aufi, Ahmed, Critchley, William R., Saikia, Queen, Homer-Vanniasinkam, Shervanthi, Sawamura, Tatsuya, McPherson, Michael J., Harrison, Michael A., Tomlinson, Darren C., Ponnambalam, Sreenivasan
Publicado 2023

Growing and dividing: how O-GlcNAcylation leads the way

por Saunders, Harmony, Dias, Wagner B., Slawson, Chad
Publicado 2023

Disease-related PSS1 mutant impedes the formation and function of osteoclasts

por Sugahara, Sari, Ishino, Yuki, Sawada, Koki, Iwata, Tsumugi, Shimanaka, Yuta, Aoki, Junken, Arai, Hiroyuki, Kono, Nozomu
Publicado 2023

LC-MS based simultaneous profiling of adrenal hormones of steroids, catecholamines, and metanephrines

por Noh, Jongsung, Lee, Chaelin, Kim, Jung Hee, Myung, Seung Woon, Choi, Man Ho
Publicado 2023

Serum opacity factor normalizes erythrocyte morphology in Scarb1(−/−) mice in an HDL-free cholesterol-dependent way

por Wang, Ziyi, Yelamanchili, Dedipya, Liu, Jing, Gotto, Antonio M., Rosales, Corina, Gillard, Baiba K., Pownall, Henry J.
Publicado 2023

A real-time analysis of protein transport via the twin arginine translocation pathway in response to different components of the protonmotive force

por Zhou, Wenjie, Hao, Binhan, Bricker, Terry M., Theg, Steven M.
Publicado 2023

Turnover and bypass of p21-activated kinase during Cdc42-dependent MAPK signaling in yeast

por González, Beatriz, Mirzaei, Mahnoosh, Basu, Sukanya, Pujari, Atindra N., Vandermeulen, Matthew D., Prabhakar, Aditi, Cullen, Paul J.
Publicado 2023

Mycobacterial RNase E cleaves with a distinct sequence preference and controls the degradation rates of most Mycolicibacterium smegmatis mRNAs

por Zhou, Ying, Sun, Huaming, Rapiejko, Abigail R., Vargas-Blanco, Diego A., Martini, Maria Carla, Chase, Michael R., Joubran, Samantha R., Davis, Alexa B., Dainis, Joseph P., Kelly, Jessica M., Ioerger, Thomas R., Roberts, Louis A., Fortune, Sarah M., Shell, Scarlet S.
Publicado 2023

A PrP EGFR signaling axis controls neural stem cell senescence through modulating cellular energy pathways

por Groveman, Bradley R., Schwarz, Benjamin, Bohrnsen, Eric, Foliaki, Simote T., Carroll, James A., Wood, Aleksandar R., Bosio, Catharine M., Haigh, Cathryn L.
Publicado 2023