Biophysical and structural characterization of the impacts of MET phosphorylation on tepotinib binding

por Grädler, Ulrich, Schwarz, Daniel, Wegener, Ansgar, Eichhorn, Thomas, Bandeiras, Tiago M., Freitas, Micael C., Lammens, Alfred, Ganichkin, Oleg, Augustin, Martin, Minguzzi, Stefano, Becker, Frank, Bomke, Jörg
Publicado 2023

IdeS, a secreted proteinase of Streptococcus pyogenes, is bound to a nuclease at the bacterial surface where it inactivates opsonizing IgG antibodies

por Frick, Inga-Maria, Happonen, Lotta, Wrighton, Sebastian, Nordenfelt, Pontus, Björck, Lars
Publicado 2023

ROR2 homodimerization is sufficient to activate a neuronal Wnt/calcium signaling pathway

por Riquelme, Raul, Li, Laura, Gambrill, Abigail, Barria, Andres
Publicado 2023

The microtubule-severing protein UNC-45A preferentially binds to curved microtubules and counteracts the microtubule-straightening effects of Taxol

por Hoshino, Asumi, Clemente, Valentino, Shetty, Mihir, Castle, Brian, Odde, David, Bazzaro, Martina
Publicado 2023

HDGF stimulates liver tumorigenesis by enhancing reactive oxygen species generation in mitochondria

por Hu, Tsung-Hui, Wu, Jian-Ching, Huang, Shih-Tsung, Chu, Tian-Huei, Han, Ai-Jie, Shih, Ting-Wei, Chang, Yi-Chen, Yang, Shih-Ming, Ko, Chou-Yuan, Lin, Yu-Wei, Kung, Mei-Lang, Tai, Ming-Hong
Publicado 2023

P-type ATPases: Many more enigmas left to solve

por Palmgren, Michael
Publicado 2023

The adaptability of the ion-binding site by the Ag(I)/Cu(I) periplasmic chaperone SilF

por Lithgo, Ryan M., Hanževački, Marko, Harris, Gemma, Kamps, Jos J.A.G., Holden, Ellie, Gianga, Tiberiu-Marius, Benesch, Justin L.P., Jäger, Christof M., Croft, Anna K., Hussain, Rohannah, Hobman, Jon L., Orville, Allen M., Quigley, Andrew, Carr, Stephen B., Scott, David J.
Publicado 2023

Global Analysis of Post-Translational Side-Chain Arginylation Using Pan-Arginylation Antibodies

por MacTaggart, Brittany, Shimogawa, Marie, Lougee, Marshall, Tang, Hsin-Yao, Petersson, E.J., Kashina, Anna
Publicado 2023

Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder

por Oguro, Ami, Fujiyama, Taichi, Ishihara, Yasuhiro, Kataoka, Chisato, Yamamoto, Megumi, Eto, Komyo, Komohara, Yoshihiro, Imaoka, Susumu, Sakuragi, Toshihide, Tsuji, Mayumi, Shibata, Eiji, Kotake, Yaichiro, Yamazaki, Takeshi
Publicado 2023

Collagen IV of basement membranes: III. Chloride pressure is a primordial innovation that drives and maintains the assembly of scaffolds

por Boudko, Sergei P., Pedchenko, Vadim K., Pokidysheva, Elena N., Budko, Alena M., Baugh, Rachel, Coates, Patrick Toby, Fidler, Aaron L., Hudson, Heather M., Ivanov, Sergey V., Luer, Carl, Pedchenko, Tetyana, Preston, Robert L., Rafi, Mohamed, Vanacore, Roberto, Bhave, Gautam, Hudson, Julie K., Hudson, Billy G.
Publicado 2023

Reactive nitrogen species inhibit branched chain alpha-ketoacid dehydrogenase complex and impact muscle cell metabolism

por Arp, Nicholas L., Seim, Gretchen L., Votava, James A., Josephson, Jordyn, Fan, Jing
Publicado 2023

Deubiquitinase UCHL1 regulates estradiol synthesis by stabilizing voltage-dependent anion channel 2

por Shi, Shengjie, Chu, Guiyan, Zhang, Lutong, Yuan, Huan, Madaniyati, Mielie, Zhou, Xiaoge, Wang, Liguang, Cai, Chuanjiang, Pang, Weijun, Gao, Lei, Yang, Gongshe
Publicado 2023

Disruption of the productive encounter complex results in dysregulation of DIAPH1 activity

por Theophall, Gregory G., Ramirez, Lisa M.S., Premo, Aaron, Reverdatto, Sergey, Manigrasso, Michaele B., Yepuri, Gautham, Burz, David S., Ramasamy, Ravichandran, Schmidt, Ann Marie, Shekhtman, Alexander
Publicado 2023

The cancer testes antigen, HORMAD1, limits genomic instability in cancer cells by protecting stalled replication forks

por Herrera, Luis Reza, Johnson, Ronnesha A., McGlynn, Kathleen, Gibbs, Zane A., Davis, Anthony J., Whitehurst, Angelique W.
Publicado 2023

The microtubule quartet protein SNAP1 in Trypanosoma brucei facilitates flagellum and cell division plane positioning by promoting basal body segregation

por Souza Onofre, Thiago, Pham, Kieu T.M., Zhou, Qing, Li, Ziyin
Publicado 2023

Wolf-Hirschhorn syndrome candidate 1 (Whsc1) methyltransferase signals via a Pitx2-miR-23/24 axis to effect tooth development

por Su, Dan, Eliason, Steve, Sun, Zhao, Shao, Fan, Amendt, Brad A.
Publicado 2023

Reversible and irreversible inhibitors of coronavirus Nsp15 endoribonuclease

por Chen, Jerry, Farraj, Rabih Abou, Limonta, Daniel, Tabatabaei Dakhili, Seyed Amir, Kerek, Evan M., Bhattacharya, Ashim, Reformat, Filip M., Mabrouk, Ola M., Brigant, Benjamin, Pfeifer, Tom A., McDermott, Mark T., Ussher, John R., Hobman, Tom C., Glover, J.N. Mark, Hubbard, Basil P.
Publicado 2023

High-speed AFM imaging reveals DNA capture and loop extrusion dynamics by cohesin-NIPBL

por Kaur, Parminder, Lu, Xiaotong, Xu, Qi, Irvin, Elizabeth Marie, Pappas, Colette, Zhang, Hongshan, Finkelstein, Ilya J., Shi, Zhubing, Tao, Yizhi Jane, Yu, Hongtao, Wang, Hong
Publicado 2023

Babesia BdFE1 esterase is required for the anti-parasitic activity of the ACE inhibitor fosinopril

por Vydyam, Pratap, Choi, Jae-Yeon, Gihaz, Shalev, Chand, Meenal, Gewirtz, Meital, Thekkiniath, Jose, Lonardi, Stefano, Gennaro, Joseph C., Ben Mamoun, Choukri
Publicado 2023

Structural basis of membrane machines that traffick and attach heme to cytochromes

por Huynh, Jonathan Q., Lowder, Ethan P., Kranz, Robert G.
Publicado 2023