A highly specific antibody against the core fucose of the N-glycan in IgG identifies the pulmonary diseases and its regulation by CCL2

por Kanto, Noriko, Ohkawa, Yuki, Kitano, Masato, Maeda, Kento, Shiida, Masafumi, Ono, Tatsuya, Ota, Fumi, Kizuka, Yasuhiko, Kunimasa, Kei, Nishino, Kazumi, Mukai, Mikio, Seike, Masahiro, Azuma, Arata, Harada, Yoichiro, Fukuda, Tomohiko, Gu, Jianguo, Taniguchi, Naoyuki
Publicado 2023

Identification of the functional PD-L1 interface region responsible for PD-1 binding and initiation of PD-1 signaling

por Carter, Rachel, Alanazi, Fatimah, Sharp, Amanda, Roman, Jessica, Luchini, Alessandra, Liotta, Lance, Paige, Mikell, Brown, Anne M., Haymond, Amanda
Publicado 2023

Metformin inhibits digestive proteases and impairs protein digestion in mice

por Kelly, Caleb J., Verdegaal, Andrew A., Anderson, Brent W., Shaw, William L., Bencivenga-Barry, Natasha A., Folta-Stogniew, Ewa, Goodman, Andrew L.
Publicado 2023

Quantitative Time-Course Analysis of Osmotic and Salt Stress in Arabidopsis thaliana Using Short Gradient Multi-CV FAIMSpro BoxCar DIA

por Rodriguez Gallo, M.C., Li, Q., Talasila, M., Uhrig, R.G.
Publicado 2023

Defining the molecular architecture, metal dependence, and distribution of metal-dependent class II sulfofructose-1-phosphate aldolases

por Sharma, Mahima, Kaur, Arashdeep, Madiedo Soler, Niccolay, Lingford, James P., Epa, Ruwan, Goddard-Borger, Ethan D., Davies, Gideon J., Williams, Spencer J.
Publicado 2023

LDL binding to cell receptors and extracellular matrix is proatherogenic in obesity but improves after bariatric surgery

por Jayaraman, Shobini, Pérez, Antonio, Miñambres, Inka, Sánchez-Quesada, Jose Luis, Gursky, Olga
Publicado 2023

Early Proteomic Characteristics and Changes in the Optic Nerve Head, Optic Nerve, and Retina in a Rat Model of Ocular Hypertension

por Lin, Danting, Wu, Shen, Cheng, Ying, Yan, Xuejing, Liu, Qian, Ren, Tianmin, Zhang, Jingxue, Wang, Ningli
Publicado 2023

Insight Into the Dynamics of the Ixodes ricinus Nymphal Midgut Proteome

por Kozelková, Tereza, Dyčka, Filip, Lu, Stephen, Urbanová, Veronika, Frantová, Helena, Sojka, Daniel, Šma, Radek, Horn, Martin, Perner, Jan, Kopáček, Petr
Publicado 2023

Deletion of hepatic small heterodimer partner ameliorates development of nonalcoholic steatohepatitis in mice

por Lee, Yoon-Kwang, Park, Jung Eun, Lee, Mikang, Mifflin, Ryan, Xu, Yang, Novak, Robert, Zhang, Yanqiao, Hardwick, James P.
Publicado 2023

Unlatching of the stem domains in the Staphylococcus aureus pore-forming leukocidin LukAB influences toxin oligomerization

por Ilmain, Juliana K., Perelman, Sofya S., Panepinto, Maria C., Irnov, Irnov, Coudray, Nicolas, Samhadaneh, Nora, Pironti, Alejandro, Ueberheide, Beatrix, Ekiert, Damian C., Bhabha, Gira, Torres, Victor J.
Publicado 2023

Cooperative lipolytic control of neuronal triacylglycerol by spastic paraplegia-associated enzyme DDHD2 and ATGL

por Hofer, Peter, Grabner, Gernot F., König, Mario, Xie, Hao, Bulfon, Dominik, Ludwig, Anton E., Wolinski, Heimo, Zimmermann, Robert, Zechner, Rudolf, Heier, Christoph
Publicado 2023

The heparin-binding hemagglutinin protein of Mycobacterium tuberculosis is a nucleoid-associated protein

por Keshavam, Chetkar Chandra, Naz, Saba, Gupta, Aanchal, Sanyal, Priyadarshini, Kochar, Manisha, Gangwal, Aakriti, Sangwan, Nitika, Kumar, Nishant, Tyagi, Ekta, Goel, Simran, Singh, Nitesh Kumar, Sowpati, Divya Tej, Khare, Garima, Ganguli, Munia, Raze, Dominique, Locht, Camille, Basu-Modak, Sharmila, Gupta, Meetu, Nandicoori, Vinay Kumar, Singh, Yogendra
Publicado 2023

E3 ubiquitin ligase ZBTB25 suppresses beta coronavirus infection through ubiquitination of the main viral protease MPro

por Lear, Travis B., Boudreau, Áine N., Lockwood, Karina C., Chu, Elise, Camarco, Daniel P., Cao, Qing, Nguyen, Matthew, Evankovich, John W., Finkel, Toren, Liu, Yuan, Chen, Bill B.
Publicado 2023

The toxicities of A30P and A53T α-synuclein fibrils can be uniquely altered by the length and saturation of fatty acids in phosphatidylserine

por Ali, Abid, Zhaliazka, Kiryl, Dou, Tianyi, Holman, Aidan P., Kurouski, Dmitry
Publicado 2023

Posttranslational modification and heme cavity architecture of human eosinophil peroxidase—insights from first crystal structure and biochemical characterization

por Pfanzagl, Vera, Gruber-Grünwald, Clemens, Leitgeb, Urban, Furtmüller, Paul G., Obinger, Christian
Publicado 2023

Lipid environment modulates processivity and kinetics of a presenilin homolog acting on multiple substrates in vitro

por Wu, Yuqi, Thomas, Gwendell M., Thomsen, Max, Bahri, Sara, Lieberman, Raquel L.
Publicado 2023

Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms

por Benner, Orion, Cast, Thomas P., Minamide, Laurie S., Lenninger, Zephyr, Bamburg, James R., Chanda, Soham
Publicado 2023

Multistep conformational changes leading to the gate opening of light-driven sodium pump rhodopsin

por Sato, Yukino, Hashimoto, Tsubasa, Kato, Koji, Okamura, Akiko, Hasegawa, Kaito, Shinone, Tsukasa, Tanaka, Yoshikazu, Tanaka, Yoshiki, Tsukazaki, Tomoya, Tsukamoto, Takashi, Demura, Makoto, Yao, Min, Kikukawa, Takashi
Publicado 2023

The solution structure of the heavy chain–only C5-Fc nanobody reveals exposed variable regions that are optimal for COVID-19 antigen interactions

por Gao, Xin, Thrush, Joseph W., Gor, Jayesh, Naismith, James H., Owens, Raymond J., Perkins, Stephen J.
Publicado 2023

An Automated Nanowell-Array Workflow for Quantitative Multiplexed Single-Cell Proteomics Sample Preparation at High Sensitivity

por Ctortecka, Claudia, Hartlmayr, David, Seth, Anjali, Mendjan, Sasha, Tourniaire, Guilhem, Udeshi, Namrata D., Carr, Steven A., Mechtler, Karl
Publicado 2023