Identification of novel plant cysteine oxidase inhibitors from a yeast chemical genetic screen

por Lavilla-Puerta, Mikel, Latter, Rebecca, Bellè, Francesca, Cervelli, Tiziana, Galli, Alvaro, Perata, Pierdomenico, Chini, Andrea, Flashman, Emily, Giuntoli, Beatrice
Publicado 2023

The Legionella autoinducer LAI-1 is delivered by outer membrane vesicles to promote interbacterial and interkingdom signaling

por Fan, Mingzhen, Kiefer, Patrick, Charki, Paul, Hedberg, Christian, Seibel, Jürgen, Vorholt, Julia A., Hilbi, Hubert
Publicado 2023

Atypical genotoxicity of carcinogenic nickel(II): Linkage to dNTP biosynthesis, DNA-incorporated rNMPs, and impaired repair of TOP1-DNA crosslinks

por Krawic, Casey, Luczak, Michal W., Valiente, Sophia, Zhitkovich, Anatoly
Publicado 2023

Cyclase-associated protein interacts with actin filament barbed ends to promote depolymerization and formin displacement

por Alimov, Nikita, Hoeprich, Gregory J., Padrick, Shae B., Goode, Bruce L.
Publicado 2023

Loss of muscle PDH induces lactic acidosis and adaptive anaplerotic compensation via pyruvate-alanine cycling and glutaminolysis

por Gopal, Keshav, Abdualkader, Abdualrahman Mohammed, Li, Xiaobei, Greenwell, Amanda A., Karwi, Qutuba G., Altamimi, Tariq R., Saed, Christina, Uddin, Golam M., Darwesh, Ahmed M., Jamieson, K. Lockhart, Kim, Ryekjang, Eaton, Farah, Seubert, John M., Lopaschuk, Gary D., Ussher, John R., Al Batran, Rami
Publicado 2023

AMPKα1 negatively regulates osteoclastogenesis and mitigates pathological bone loss

por Ribeiro, Mariana S.P., Venturini, Lucas G.R., Speck-Hernandez, Cesar A., Alabarse, Paulo V.G., Xavier, Thais, Taira, Thaise M., Duffles, Letícia F., Cunha, Fernando Q., Fukada, Sandra Y.
Publicado 2023

SARS-CoV-2 papain-like protease plays multiple roles in regulating cellular proteins in the endoplasmic reticulum

por Yang, Mei, Mariano, Jennifer, Su, Rebecca, Smith, Christopher E., Das, Sudipto, Gill, Catherine, Andresson, Thorkell, Loncarek, Jadranka, Tsai, Yien Che, Weissman, Allan M.
Publicado 2023

Protein arginine N-methyltransferase 2 plays a noncatalytic role in the histone methylation activity of PRMT1

por Rowley, Michael J., Prout-Holm, Riley A., Liu, Rui Wen, Hendrickson-Rebizant, Thordur, Ige, Olufola O., Lakowski, Ted M., Frankel, Adam
Publicado 2023

Characterization of erythroferrone structural domains relevant to its iron-regulatory function

por Srole, Daniel N., Jung, Grace, Waring, Alan J., Nemeth, Elizabeta, Ganz, Tomas
Publicado 2023

Cell aggregation activates small GTPase Rac1 and induces CD44 cleavage by maintaining lipid raft integrity

por Li, Dong, Park, Younhee, Hemati, Hami, Liu, Xia
Publicado 2023

The Arabidopsis SWEET1 and SWEET2 uniporters recognize similar substrates while differing in subcellular localization

por Gwon, Sojeong, Park, Jihyun, Huque, AKM Mahmudul, Cheung, Lily S.
Publicado 2023

A conserved core region of the scaffold NEMO is essential for signal-induced conformational change and liquid-liquid phase separation

por DiRusso, Christopher J., DeMaria, Anthony M., Wong, Judy, Wang, Wei, Jordanides, Jack J., Whitty, Adrian, Allen, Karen N., Gilmore, Thomas D.
Publicado 2023

Sialidase NEU3 action on GM1 ganglioside is neuroprotective in GM1 gangliosidosis

por Allende, Maria L., Lee, Y. Terry, Byrnes, Colleen, Li, Cuiling, Tuymetova, Galina, Bakir, Jenna Y., Nicoli, Elena-Raluca, James, Virginia K., Brodbelt, Jennifer S., Tifft, Cynthia J., Proia, Richard L.
Publicado 2023

An siRNA library screen identifies CYLD and USP34 as deubiquitinases that regulate GPCR-p38 MAPK signaling and distinct inflammatory responses

por Cheng, Norton, Trejo, JoAnn
Publicado 2023

Binding of perilipin 3 to membranes containing diacylglycerol is mediated by conserved residues within its PAT domain

por Stribny, Jiri, Schneiter, Roger
Publicado 2023

Redirecting the specificity of tripartite motif containing-21 scaffolds using a novel discovery and design approach

por VanDyke, Derek, Xu, Linda, Sargunas, Paul R., Gilbreth, Ryan N., Baca, Manuel, Gao, Changshou, Hunt, James, Spangler, Jamie B.
Publicado 2023

cAMP competitively inhibits periplasmic phosphatases to coordinate nutritional growth with competence of Haemophilus influenzae

por Kronborg, Kristina, Zhang, Yong Everett
Publicado 2023

Beta-cell compensation and gestational diabetes

por Usman, Taofeek O., Chhetri, Goma, Yeh, Hsuan, Dong, H. Henry
Publicado 2023

More is different: Reconstituting complexity in microtubule regulation

por Lawrence, Elizabeth J., Chatterjee, Saptarshi, Zanic, Marija
Publicado 2023

Human Fis1 directly interacts with Drp1 in an evolutionarily conserved manner to promote mitochondrial fission

por Nolden, Kelsey A., Harwig, Megan C., Hill, R. Blake
Publicado 2023