The N‐Acetylgalactosamine‐conjugated small interfering RNA inclisiran can be coadministered safely with atorvastatin in cynomolgus monkeys resulting in additive low‐density lipopro...

por Lehoux, Dario, Kallend, David, Wijngaard, Peter L. J., Brown, Alan P., Zerler, Brad
Publicado 2023

Hypoviral‐regulated HSP90 co‐chaperone p23 (CpCop23) determines the colony morphology, virulence, and viral response of chestnut blight fungus Cryphonectria parasitica

por Ko, Yo‐Han, Chun, Jeesun, Yang, Han‐Eul, Kim, Dae‐Hyuk
Publicado 2023

Clinical, contextual and hospital-level factors associated with escalation and de-escalation of empiric Gram-negative antibiotics among US inpatients

por Baghdadi, Jonathan D, Goodman, Katherine E, Magder, Laurence S, Heil, Emily L, Claeys, Kimberly, Bork, Jacqueline, Harris, Anthony D
Publicado 2023

Yersinia pestis genomes reveal plague in Britain 4000 years ago

por Swali, Pooja, Schulting, Rick, Gilardet, Alexandre, Kelly, Monica, Anastasiadou, Kyriaki, Glocke, Isabelle, McCabe, Jesse, Williams, Mia, Audsley, Tony, Loe, Louise, Fernández-Crespo, Teresa, Ordoño, Javier, Walker, David, Clare, Tom, Cook, Geoff, Hodkinson, Ian, Simpson, Mark, Read, Stephen, Davy, Tom, Silva, Marina, Hajdinjak, Mateja, Bergström, Anders, Booth, Thomas, Skoglund, Pontus
Publicado 2023

Exploring the epidemiology of mcr genes, genetic context and plasmids in Enterobacteriaceae originating from pigs and humans on farms in Thailand

por Leangapichart, Thongpan, Stosic, Milan S, Hickman, Rachel A, Lunha, Kamonwan, Jiwakanon, Jatesada, Angkititrakul, Sunpetch, Magnusson, Ulf, Van Boeckel, Thomas P, Järhult, Josef D, Sunde, Marianne
Publicado 2023

In vitro activity of cefiderocol against MBL-producing Gram-negative bacteria collected in North America and Europe in five consecutive annual multinational SIDERO-WT surveillance...

por Takemura, Miki, Wise, Mark G, Hackel, Meredith A, Sahm, Daniel F, Yamano, Yoshinori
Publicado 2023

Primary prophylaxis of invasive fungal diseases in patients with haematological malignancies: 2022 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of...

por Stemler, Jannik, Mellinghoff, Sibylle C, Khodamoradi, Yascha, Sprute, Rosanne, Classen, Annika Y, Zapke, Sonja E, Hoenigl, Martin, Krause, Robert, Schmidt-Hieber, Martin, Heinz, Werner J, Klein, Michael, Koehler, Philipp, Liss, Blasius, Koldehoff, Michael, Buhl, Christoph, Penack, Olaf, Maschmeyer, Georg, Schalk, Enrico, Lass-Flörl, Cornelia, Karthaus, Meinolf, Ruhnke, Markus, Cornely, Oliver A, Teschner, Daniel
Publicado 2023

O03 The effect of antibiotic selection on collateral susceptibility and evolvability of uropathogenic Escherichia coli

por Hubbard, Alasdair T M, James, Beth, Whelan, Rachel, Meehan, Conor, Domingo Sananes, Maria Rosa
Publicado 2023

A comparison of peripheral blood stem cell collection outcomes for multiple myeloma; mobilization matters in the era of IMiD induction

por Chandler, Thea, Parrish, Christopher, Karakantza, Marina, Carmichael, Jonathan, Pawson, David, Cook, Gordon, Seymour, Frances
Publicado 2023

Carbapenem resistance in Enterobacterales bloodstream infections among children with cancer or post-haematopoietic stem cell transplant: a retrospective cohort study

por López-Cubillos, Juan F, Díaz, Alejandro, Cárdenas, Vicky C, Camacho-Moreno, German, Cantor, Erika, Arcila, Eliana M, Hurtado, Isabel C, Correa, Adriana M, Tierradentro, Tatiana M, Ramirez, Oscar, Portilla, Carlos A, Aponte-Barrios, Nelson, López, Pio, Torres, Daniela, Bustos-Paz, Mario, Bravo, Ana M, Escobar, Janeth J, Calle, Juan P, Dávalos, Diana M, López-Medina, Eduardo
Publicado 2023

In vitro activity of cefiderocol against Pseudomonas aeruginosa demonstrating evolved resistance to novel β-lactam/β-lactamase inhibitors

por Shields, Ryan K, Kline, Ellen G, Squires, Kevin M, Van Tyne, Daria, Doi, Yohei
Publicado 2023

Mutations in ompK36 differentially impact in vitro synergy of meropenem/vaborbactam and ceftazidime/avibactam in combination with other antibiotics against KPC-producing Klebsiella...

por Rogers, Tara M, Kline, Ellen G, Griffith, Marissa P, Jones, Chelsea E, Rubio, Abigail M, Squires, Kevin M, Shields, Ryan K
Publicado 2023

Antiplatelet therapy and incident cognitive impairment or dementia—a systematic review and meta-analysis of randomised clinical trials

por Kitt, Kevin, Murphy, Robert, Clarke, Aoibhin, Reddin, Catriona, Ferguson, John, Bosch, Jackie, Whiteley, William, Canavan, Michelle, Judge, Conor, O’Donnell, Martin
Publicado 2023

Real‐world experience of novel multiple myeloma treatments in a large, single‐center cohort in Finland

por Loponen, Heidi, Mehtälä, Juha, Ylisaukko‐oja, Tero, Brück, Oscar, Porkka, Kimmo, Koskenvesa, Perttu, Saukkonen, Kirsi, Lievonen, Juha
Publicado 2023

Prevalence and antimicrobial susceptibility pattern of methicillin resistant Staphylococcus aureus isolates from Trinidad & Tobago

por Akpaka, Patrick Eberechi, Kissoon, Shivnarine, Swanston, William Henry, Monteil, Michele
Publicado 2006

Antibacterial resistance and their genetic location in MRSA isolated in Kuwait hospitals, 1994-2004

por Udo, Edet E, Al-Sweih, Noura, Mokaddas, Eiman, Johny, Molly, Dhar, Rita, Gomaa, Huda H, Al-Obaid, Inaam, Rotimi, Vincent O
Publicado 2006

Mechanisms of nordihydroguaiaretic acid-induced growth inhibition and apoptosis in human cancer cells

por Seufferlein, T, Seckl, M J, Schwarz, E, Beil, M, v Wichert, G, Baust, H, Lührs, H, Schmid, R M, Adler, G
Publicado 2002

A phase II trial of the vitamin D analogue Seocalcitol (EB1089) in patients with inoperable pancreatic cancer

por Evans, T R J, Colston, K W, Lofts, F J, Cunningham, D, Anthoney, D A, Gogas, H, de Bono, J S, Hamberg, K J, Skov, T, Mansi, J L
Publicado 2002

Cytotoxicity of rhein, the active metabolite of sennoside laxatives, is reduced by multidrug resistance-associated protein 1

por van Gorkom, B A P, Timmer-Bosscha, H, de Jong, S, van der Kolk, D M, Kleibeuker, J H, de Vries, E G E
Publicado 2002

Effect of non-steroidal anti-inflammatory drugs on colon carcinoma Caco-2 cell responsiveness to topoisomerase inhibitor drugs

por Ricchi, P, Matola, T Di, Ruggiero, G, Zanzi, D, Apicella, A, di Palma, A, Pensabene, M, Pignata, S, Zarrilli, R, Acquaviva, A M
Publicado 2002