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1001por Marty, C, Odermatt, B, Schott, H, Neri, D, Ballmer-Hofer, K, Klemenz, R, Schwendener, R A“…Animals treated i.v. with single chain antibody fragments-liposomes containing the new cytotoxic agent 2′-deoxy-5-fluorouridylyl-N(4)-octadecyl-1-β-D-arabinofuranosylcytosine (30 mg kg(-1) per dose, five times every 24 h) showed a reduction of tumour growth by 62–90% determined on days 5 and 8, respectively, compared to animals receiving control liposomes. …”
Publicado 2002
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1002“…Taken together, these results implicate RGD-peptides as agents which have anti-tumour and anti-metastatic activity in vivo. …”
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1003“…One strategy to improve the outcome for patients is to add other agents to standard therapy. Doxil is active in relapsed disease and has a response rate of 25% in platinum-resistant relapsed disease. …”
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1004“…These data indicate that keratinocyte-fibroblast interactions are mediated by multiple stimulating agents acting on specific receptors to induce signalling through different mitogen-activated protein kinase pathways leading to altered expression of key biological functions. …”
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1005por Salgado, R, Benoy, I, Weytjens, R, Van Bockstaele, D, Van Marck, E, Huget, Ph, Hoylaerts, M, Vermeulen, P, Dirix, L Y“…This might be of importance in the development of anti-angiogenic agents based on interference with haemostasis. British Journal of Cancer (2002) 87, 1437–1444. doi:10.1038/sj.bjc.6600655 www.bjcancer.com © 2002 Cancer Research UK…”
Publicado 2002
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1006por Veater, James, Mehedi, Farhan, Cheung, Chee Kay, Nabarro, Laura, Osborne, Jane, Wong, Nicholas, Wiselka, Martin, Tang, Julian W“…BACKGROUND: Elderly patients have a long list of differentials for causes of acute confusion and altered consciousness levels, including infectious agents. In addition, elderly, retired patients often have more time to travel for tourism, particularly to exotic, warmer locations. …”
Publicado 2017
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1007por Bath, Philip M, Woodhouse, Lisa J, Appleton, Jason P, Beridze, Maia, Christensen, Hanne, Dineen, Robert A, Duley, Lelia, England, Timothy J, Flaherty, Katie, Havard, Diane, Heptinstall, Stan, James, Marilyn, Krishnan, Kailash, Markus, Hugh S, Montgomery, Alan A, Pocock, Stuart J, Randall, Marc, Ranta, Annemarei, Robinson, Thompson G, Scutt, Polly, Venables, Graham S, Sprigg, Nikola“…BACKGROUND: Intensive antiplatelet therapy with three agents might be more effective than guideline treatment for preventing recurrent events in patients with acute cerebral ischaemia. …”
Publicado 2018
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1008por Conn, P Jeffrey“…Jeff Conn (Vanderbilt Univ., USA) will summarize recent genetic studies that point to loss of function mutations in two novel G protein-coupled receptors in SCZ patients, and the discovery of novel positive allosteric modulators for these receptors that are providing a strong proof of concept for advancing selective agents to clinical evaluation in patients, including those that bear these specific mutations. …”
Publicado 2018
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1009por Peter, Emanuel L., Deyno, Serawit, Mtewa, Andrew, Kasali, Félicien Mushagalusa, Nagendrappa, Prakash B., Sesaazi, Duncan, Tolo, Casim Umba, Ogwang, Patrick Engeu“…The included studies will have assessed glycemic control of M. charantia preparations with placebo or standard oral anti-hyperglycemic agents in adult pre-diabetes and/or type 2 diabetes mellitus patients and have at least 4 weeks of follow-up. …”
Publicado 2018
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1010por Russell, Steven J, Sala, Robert, Conaghan, Philip G, Habib, George, Vo, Quang, Manning, Rickey, Kivitz, Alan, Davis, Yvonne, Lufkin, Joelle, Johnson, James R, Kelley, Scott, Bodick, NeilEnlace del recurso
Publicado 2018
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1012por Prabhu, A, Brandl, A, Wakama, S, Sako, S, Ishibashi, H, Mizumoto, A, Takao, N, Ichinose, M, Motoi, S, Liu, Y, Yonemura, YEnlace del recurso
Publicado 2021
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1013por Harvala, Heli, Robb, Matthew L., Watkins, Nick, Ijaz, Samreen, Dicks, Steven, Patel, Monika, Supasa, Piyada, Wanwisa, Dejnirattisai, Liu, Chang, Mongkolsapaya, Juthathip, Bown, Abbie, Bailey, Daniel, Vipond, Richard, Grayson, Nicholas, Temperton, Nigel, Gupta, Sunetra, Ploeg, Rutger J., Bolton, Jai, Fyfe, Alex, Gopal, Robin, Simmonds, Peter, Screaton, Gavin, Thompson, Craig, Brooks, Tim, Zambon, Maria, Miflin, Gail, Roberts, David J.Enlace del recurso
Publicado 2020
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1014por Shamsoddin, ErfanEnlace del recurso
Publicado 2021
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1015por Sime, Fekade B., Wallis, Steven C., Jamieson, Conor, Hills, Tim, Gilchrist, Mark, Santillo, Mark, Seaton, R. Andrew, Drummond, Felicity, Roberts, Jason A.Enlace del recurso
Publicado 2022
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1016“…Clinical remission was reported in 61.8% of patients on their first biologic agent at the last follow up. CONCLUSIONS: Factors influencing earlier progression to biologics were disease severity and disease behaviour. …”
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1017por Nastoupil, Loretta J., Kuruvilla, John, Chavez, Julio C., Bijou, Fontanet, Witzig, Thomas E., Santoro, Armando, Flinn, Ian W., Boccomini, Carola, Kenkre, Vaishalee P., Corradini, Paolo, Isufi, Iris, Andorsky, David J., Klein, Leonard M., Greenwald, Daniel R., Sangha, Randeep, Shen, Frank, Hagner, Patrick, Li, Yan, Dobmeyer, Juergen, Gong, Nian, Uttamsingh, Shailaja, Pourdehnad, Michael, Ribrag, VincentEnlace del recurso
Publicado 2022
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1018por Naito, Toshio, Suzuki, Mai, Fukushima, Shinichi, Yuda, Mayumi, Fukui, Nobuyuki, Tsukamoto, Shotaro, Fujibayashi, Kazutoshi, Goto‐Hirano, Keiko, Kuwatsuru, RyoheiEnlace del recurso
Publicado 2021
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1019por Jalal, M, Sakhi, A, Ansari, G. Benbrahim, Aboufaris, H, Bouayed, K, Ameayou, S, Hassoun, S, Nani, SEnlace del recurso
Publicado 2022
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