Construction of a fusion plasmid containing the PSCA gene and cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) and its anti-tumor effect in an animal model of prostate cancer

por Mai, T.J., Ma, R., Li, Z., Bi, S.C.
Publicado 2016

Non-clinical studies required for new drug development - Part I: early in silico and in vitro studies, new target discovery and validation, proof of principles and robustness of an...

por Andrade, E.L., Bento, A.F., Cavalli, J., Oliveira, S.K., Freitas, C.S., Marcon, R., Schwanke, R.C., Siqueira, J.M., Calixto, J.B.
Publicado 2016

High-CHO diet increases post-exercise oxygen consumption after a supramaximal exercise bout

por Ferreira, G.A., Bertuzzi, R., De-Oliveira, F.R., Pires, F.O., Lima-Silva, A.E.
Publicado 2016

Aerobic training modulates T cell activation in elderly women with knee osteoarthritis

por Gomes, W.F., Lacerda, A.C.R., Brito-Melo, G.E.A., Fonseca, S.F., Rocha-Vieira, E., Leopoldino, A.A.O., Amorim, M.R., Mendonça, V.A.
Publicado 2016

Maternal protein restriction during lactation modulated the expression and activity of rat offspring hepatic CYP1A1, CYP1A2, CYP2B1, CYP2B2, and CYP2E1 during development

por Da Costa, N. Meireles, Visoni, S.B.C., Dos Santos, I.L., Barja-Fidalgo, T.C., Ribeiro-Pinto, L.F.
Publicado 2016

Surgical treatment of Denis type B thoracolumbar burst fracture with neurological deficiency by paraspinal approach

por Wu, H., Zhao, D.-X., Jiang, R., Zhou, X.-Y.
Publicado 2016

Selection of superior bifidobacteria in the presence of rotavirus

por Alp Avci, G.
Publicado 2016

Effects of perinatal exposure to nonylphenol on delivery outcomes of pregnant rats and inflammatory hepatic injury in newborn rats

por Yu, J., Luo, Y., Yang, X.F., Yang, M.X., Yang, J., Yang, X.S., Zhou, J., Gao, F., He, L.T., Xu, J.
Publicado 2016

ADME studies and preliminary safety pharmacology of LDT5, a lead compound for the treatment of benign prostatic hyperplasia

por Noël, F., Nascimento-Viana, J.B., Romeiro, L.A.S., Silva, R.O., Lemes, L.F.N., Oliveira, A.S., Giorno, T.B.S., Fernandes, P.D., Silva, C.L.M.
Publicado 2016

Glucagon-like peptide 1 improves insulin resistance in vitro through anti-inflammation of macrophages

por Guo, C., Huang, T., Chen, A., Chen, X., Wang, L., Shen, F., Gu, X.
Publicado 2016

Lithium carbonate and coenzyme Q10 reduce cell death in a cell model of Machado-Joseph disease

por Lopes-Ramos, C.M., Pereira, T.C., Dogini, D.B., Gilioli, R., Lopes-Cendes, I.
Publicado 2016

Non-clinical studies in the process of new drug development - Part II: Good laboratory practice, metabolism, pharmacokinetics, safety and dose translation to clinical studies

por Andrade, E.L., Bento, A.F., Cavalli, J., Oliveira, S.K., Schwanke, R.C., Siqueira, J.M., Freitas, C.S., Marcon, R., Calixto, J.B.
Publicado 2016

Different methods of calculating ankle-brachial index in mid-elderly men and women: the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

por Miname, M., Bensenor, I.M., Lotufo, P.A.
Publicado 2016

Propofol inhibits invasion and growth of ovarian cancer cells via regulating miR-9/NF-κB signal

por Huang, X., Teng, Y., Yang, H., Ma, J.
Publicado 2016

Mannose-binding lectin 2 (Mbl2) gene polymorphisms are related to protein plasma levels, but not to heart disease and infection by Chlamydia

por Queiroz, M.A.F., Gomes, S.T.M., Almeida, N.C.C., Souza, M.I.M., Costa, S.R.C.F., Hermes, R.B., Lima, S.S., Zaninotto, M.M., Fossa, M.A.A., Maneschy, M.A., Martins-Feitosa, R.N., Azevedo, V.N., Machado, L.F.A., Ishak, M.O.G., Ishak, R., Vallinoto, A.C.R.
Publicado 2016

Iodine-131 treatment of thyroid cancer cells leads to suppression of cell proliferation followed by induction of cell apoptosis and cell cycle arrest by regulation of B-cell transl...

por Zhao, L.M., Pang, A.X.
Publicado 2017

Swimming training prevents coronary endothelial dysfunction in ovariectomized spontaneously hypertensive rats

por Claudio, E.R.G., Almeida, S.A., Mengal, V., Brasil, G.A., Santuzzi, C.H., Tiradentes, R.V., Gouvea, S.A., Bissoli, N.S., Santos, R.L., Abreu, G.R.
Publicado 2017

Survival benefits of interferon-based therapy in patients with recurrent hepatitis C after orthotopic liver transplantation

por Zanaga, L.P., Vigani, A.G., Angerami, R.N., Giorgetti, A., Escanhoela, C.A.F., Ataíde, E.C., Boin, I.F.S.F., Stucchi, R.S.B.
Publicado 2017

A broad pH range and processive chitinase from a metagenome library

por Thimoteo, S.S., Glogauer, A., Faoro, H., de Souza, E.M., Huergo, L.F., Moerschbacher, B.M., Pedrosa, F.O.
Publicado 2017

A simple and efficient method for poly-3-hydroxybutyrate quantification in diazotrophic bacteria within 5 minutes using flow cytometry

por Alves, L.P.S., Almeida, A.T., Cruz, L.M., Pedrosa, F.O., de Souza, E.M., Chubatsu, L.S., Müller-Santos, M., Valdameri, G.
Publicado 2017