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2por Fornelos, Nadine, Butala, Matej, Hodnik, Vesna, Anderluh, Gregor, Bamford, Jaana K., Salas, Margarita“…Our findings suggest that gp7 induces a LexA conformation that favors DNA binding but disfavors LexA auto-cleavage, thereby altering the dynamics of the cellular SOS response. …”
Publicado 2015
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3por Silva, B.C.R., Andrade, M.O., Bertholucci, G.P., Carneiro, J.F., Fernandes, J.F., Gomes, B.M.S., Gomes, T.C.A., Katopodis, P.P., Moraes, L.F.M., Silva, A.M.T.C.Enlace del recurso
Publicado 2020
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4por Caillat, Christophe, Guilligay, Delphine, Sulbaran, Guidenn, Weissenhorn, Winfried“…We further discuss MPER bnAb binding to lipids and the role of somatic mutations in recognizing a bipartite epitope composed of the conserved MPER sequence and membrane components. The problematic of gp41 HR1 access and MPER bnAb auto- and polyreactivity is developed in the light of inducing such antibodies by vaccination.…”
Publicado 2020
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6Epinephrine auto-injector prescriptions to food-allergic patients in primary care in The Netherlandspor Saleh-Langenberg, Jacquelien, Dubois, A. E. J., Groenhof, F., Kocks, J. W. H., van der Molen, T., Flokstra-de Blok, B. M. J.“…METHODS: Patients aged 12–23 years who consulted their GP for allergic symptoms were identified in a primary care database. …”
Publicado 2015
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7por Takasawa, Naruhiko, Ishii, Naoto, Higashimura, Norikazu, Murata, Kazuko, Tanaka, Yuetsu, Nakamura, Masataka, Sasaki, Takeshi, Sugamura, Kazuo“…gp34, which we previously cloned, is a ligand of OX40 (CD 134), a costimulatory molecule involved in T cell activation. …”
Publicado 2001
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8por Mercado-Camargo, Jairo, Cervantes-Ceballos, Leonor, Vivas-Reyes, Ricardo, Pedretti, Alessandro, Serrano-García, María Luisa, Gómez-Estrada, Harold“…Best docking configurations were identified applying AutoDock Vina in PyRx 0.8 to obtain a potential antileishmanial activity. …”
Publicado 2020
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9“…BACKGROUND: Adrenaline auto-injectors (AAI) should be provided to individuals considered to be at high risk of anaphylaxis. …”
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10por Pisareva, Ekaterina, Badiou, Stephanie, Mihalovičová, Lucia, Mirandola, Alexia, Pastor, Brice, Kudriavtsev, Andrei, Berger, Marie, Roubille, Camille, Fesler, Pierre, Klouche, Kada, Cristol, Jean‐Paul, Thierry, Alain R.Enlace del recurso
Publicado 2022
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11por Boeckh, Michael, Arvin, Ann, Mullane, Kathleen, Winston, Drew J, Brown, Janice (Wes), Pergam, Steven, Hurtado, Kimberly, Pang, Lei, Lee, Ingi, Popmihajlov, Zoran“…BACKGROUND: Recipients of auto-HSCT have an increased risk of herpes zoster (HZ) infection; however, live attenuated varicella-zoster virus (VZV) vaccine is contraindicated in these patients. …”
Publicado 2017
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12por Radzi, Siti Fairuz Mat, Karim, Muhammad Khalis Abdul, Saripan, M Iqbal, Rahman, Mohd Amiruddin Abd, Isa, Iza Nurzawani Che, Ibahim, Mohammad Johari“…Automated machine learning (AutoML) has been recognized as a powerful tool to build a system that automates the design and optimizes the model selection machine learning (ML) pipelines. …”
Publicado 2021
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13“…The initial structures were minimized in Gromacs to avoid crystal packing effects, and then subjected to docking experiments using AutoDock4, FireDock, ClusPro and ZDock. In molecular dynamics, the Gibbs free binding energy was calculated for the gp120-CD4 complexes. …”
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14“…We present the first crystal structure containing a clade C gp120 envelope. The structure, a complex between gp120, the host receptor CD4, and the CD4-induced antibody 21c, reveals that the 21c epitope involves contacts with gp120, a non-self antigen, and with CD4, an auto-antigen. …”
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15por Ram, Thrigulla Saketh, Munikumar, Manne, Raju, Vankudavath Naik, Devaraj, Parasannanavar, Boiroju, Naveen Kumar, Hemalatha, Rajkumar, Prasad, P.V.V., Gundeti, Manohar, Sisodia, Brijesh S., Pawar, Sharad, Prasad, G.P., Chincholikar, Mukesh, Goel, Sumeet, Mangal, Anupam, Gaidhani, Sudesh, Srikanth, N., Dhiman, K.S.Enlace del recurso
Publicado 2022
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16por Lopens, Steffi, Krawczyk, Marcin, Papp, Maria, Milkiewicz, Piotr, Schierack, Peter, Liu, Yudong, Wunsch, Ewa, Conrad, Karsten, Roggenbuck, Dirk“…Not surprisingly, the report of an association between GP2 IgA autoAbs and disease severity in patients with PSC gave a new impetus to autoAb research for autoimmune liver diseases. …”
Publicado 2020
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17“…Also for detecting falls while walking, we propose to recycle the latent samples generated in training the auto-encoded Gaussian process dynamical model for GP-based novelty detection, which can lead to an efficient and seamless solution to the detection task. …”
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18por Boots, Annemieke MH, Hubers, Henk, Kouwijzer, Milou, den Hoed-van Zandbrink, Leontien, Westrek-Esselink, Bernice M, van Doorn, Cindy, Stenger, Rachel, Bos, Ebo S, van Lierop, Marie-jose C, Verheijden, Gijs F, Timmers, Cornelis M, van Staveren, Catharina J“…We sought to identify an altered peptide ligand (APL) based on the endogenously expressed synovial auto-epitope of human cartilage glycoprotein-39 (HC gp-39) for modulation of cognate, HLA-DR4-restricted T cells. …”
Publicado 2007
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19por Boeckh, Michael J, Arvin, Ann M, Mullane, Kathleen M, Camacho, Luis H, Winston, Drew J, Morrison, Vicki A, Hurtado, Kimberly, Durrand Hall, Jessie, Pang, Lei, Su, Shu-Chih, Kaplan, Susan S, Annunziato, Paula W, Popmihajlov, Zoran“…RESULTS: Estimated geometric mean fold rise ratios (ZV(IN)/placebo) by gpELISA and IFN-y ELISPOT ~28 days post–dose 4 were 2.02 (95% confidence interval [CI], 1.53–2.67) and 5.41 (95% CI, 3.60–8.12) in auto-HSCT recipients; 1.88 (95% CI, 1.79–1.98) and 2.10 (95% CI, 1.69–2.62) in patients with STMc; and not assessed and 2.35 (95% CI, 1.81–3.05) in patients with HM. …”
Publicado 2020
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20“…MOTIVATION: Automated machine learning (AutoML) systems are helpful data science assistants designed to scan data for novel features, select appropriate supervised learning models and optimize their parameters. …”
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