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Mostrando 1 - 20 Resultados de 508 Para Buscar 'Bach Revival~', tiempo de consulta: 4.11s Limitar resultados
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    Color, Music, and Emotion: Bach to the Blues
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    “…Furthermore, our network analysis revealed that Bach’s harmony patterns were having the most influence on those used by other composers, followed closely by Mozart.…”
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    Bach Is the Father of Harmony: Revealed by a 1/f Fluctuation Analysis across Musical Genres
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    “…Genes regulated by BACH2 were very significantly over-represented among our differentially expressed genes (P<2.2x10(-16)) indicating that reduced expression of this master regulator of T cell differentiation promotes a pro-inflammatory response and strongly corroborates genetic evidence that BACH2 plays an important role in CD pathogenesis.…”
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    Transcriptome Analysis of CD4+ T Cells in Coeliac Disease Reveals Imprint of BACH2 and IFNγ Regulation
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    “…This review enlists the molecular players which interact with BACH1 to regulate DNA metabolic functions, thereby revealing its potential for cancer therapeutics. …”
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    The repair gene BACH1 - a potential oncogene
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    “…Functional analysis revealed that CBD regulated pathways involved in keratinocyte differentiation, skin development and epidermal cell differentiation among other processes. …”
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    Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1
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    “…Our study was aimed to investigate the BACH2 variant, rs3757247, in endocrine autoimmunity in the Polish population. …”
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    Polymorphism in BACH2 gene is a marker of polyglandular autoimmunity
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    “…Immunofluorescence and electron microscopy revealed larger granules in BACH2‐deficient compared to wild‐type CTLs, and proteomic analysis showed an increase in granule content, including perforin and granzymes. …”
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    Super‐killer CTLs are generated by single gene deletion of Bach2
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    A cell-based bioluminescence assay reveals dose-dependent and contextual repression of AP-1-driven gene expression by BACH2
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    “…In conclusion, our study revealed that knockdown of Bach1 effectively rescued the osteogenesis and oxidative stress of PDLCs with inflammation. …”
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    Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage
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    “…Moreover, an increase in genome-wide DNA methylation was observed in erythroblasts of Bach1(−/−) mice under iron deficiency. These findings reveal the principle role of iron as a regulator of gene expression in erythroblast maturation and suggest that the iron-heme-Bach1 axis is important for a proper adaptation of erythroblast to iron deficiency to avoid toxic aggregates of non-heme globin.…”
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    Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency
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    “…Assessment of the genome-wide function of Bach2, however, revealed that it represses genes associated with effector cell differentiation. …”
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    Bach2 represses effector programmes to stabilize T(reg)-mediated immune homeostasis
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    “…Despite this reduction, we observed increased frequencies of Tbet(+) IFNγ(+) CD4(+) (Th1) cells and IL-10-producing Th1 (Tr1) cells in mice lacking Bach2 expression by T cells. Studies in mixed bone marrow chimeric mice revealed T cell intrinsic effects of BACH2 on hematopoietic cell development, and in particular, the generation of CD4(+) and CD8(+) T cell subsets. …”
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    The Role of BACH2 in T Cells in Experimental Malaria Caused by Plasmodium chabaudi chabaudi AS
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    “…Taken together, these data have shown for the first time a possible prognostic role for BACH2 in CLL and have revealed protein interaction networks shared by BCL6 and BACH2, indicating a significant role for BACH2 and BCL6 in key cellular processes, including ubiquitination mediated B-cell receptor functions, nucleic acid metabolism, protein degradation, and homeostasis in CLL biology.…”
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    Low BACH2 Expression Predicts Adverse Outcome in Chronic Lymphocytic Leukaemia
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    Bach Adsorption Study for the Extraction of Silver Ions by Hydrazone Compounds from Aqueous Solution
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    “…Single-cell transcriptomics and epigenomics approaches revealed that BACH2 establishes the transcriptional and epigenetic programs of stem-like CD8(+) T cells. …”
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    BACH2 Enforces the Transcriptional and Epigenetic Programs of Stem-Like CD8(+) T cells
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    “…Analysis of expression profiles upon RyR2 knockdown and inhibition, revealed a set of metastasis‐related molecules, and identified BTB domain and CNC homolog 1 (BACH1) as the main transcription factor regulated by RyR2. …”
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    Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis
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    “…Further investigation revealed that BACH1 activation significantly enhanced the expression of MGMT, and depletion of p53 disrupted the effects of BACH1 on MGMT and temozolomide resistance. …”
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    BACH1 Promotes Temozolomide Resistance in Glioblastoma through Antagonizing the Function of p53
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    “…These findings reveal a critical role of the Menin-Bach2 pathway in regulating CD4 T-cell senescence and cytokine homeostasis, thus indicating the involvement of this pathway in the inhibition of immunosenescence.…”
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    The Menin–Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis
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    “…Thus, BACH1 confers an additional level of regulation to ARE-dependent genes that reveals a new dimension to the oxidative stress response.…”
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    Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1
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    “…The growing list of BACH1 target genes in cancer cells reveals that BACH1 promotes metastasis by regulating various sets of genes beyond iron metabolism. …”
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    The transcription factor BACH1 at the crossroads of cancer biology: From epithelial–mesenchymal transition to ferroptosis
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