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641por Pham, Phuong, Malik, Sohail, Mak, Chiho, Calabrese, Peter C, Roeder, Robert G, Goodman, Myron F“…Mutations are correlated over a 15 nt distance in multiply mutated clones, suggesting that deaminations are catalyzed processively within a stalled or backtracked transcription bubble. Site-by-site comparisons for biochemical and human memory B-cell mutational spectra in an IGHV3-23*01 target show strongly favored deaminations occurring in the antigen-binding complementarity determining regions (CDR) compared to the framework regions (FW). …”
Publicado 2019
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642por Klosa, Jan, Simon, Noah, Westermark, Pål Olof, Liebscher, Volkmar, Wittenburg, Dörte“…The step size between consecutive iterations is determined with backtracking line search. Finally, seagull -the R package presented here- produces complete regularization paths. …”
Publicado 2020
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643“…In contrast, Pol II backtracking was observed at the proximal transcriptional pausing sites induced by both NTS and TS slip-out blockage. …”
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644“…At the same time, the supplementary search is carried out through literature backtracking, Google Scholar. RESULTS: This study will provide new evidence for the effect of INT on the recovery of joint injury. …”
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645“…The PcrA DNA helicase contributes to unwinding RNA from the template strand, backtracking the RNA polymerase, rescuing replication-transcription conflicts, and disassembling RecA from single-stranded DNA (ssDNA) by poorly understood mechanisms. …”
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646“…The SI techniques utilized to compute the hidden states of the HMM are Particle Swarm Optimization (PSO), Differential Evolution (DE), Whale Optimization Algorithm (WOA), and Backtracking Search Algorithm (BSA), thereby making the HMM more pliable. …”
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647“…This leads to a remarkable variety of applications, allowing us to achieve optimizations under multiple objective functions, alternative solutions and backtracing, holistic search space analysis, ambiguity checking, and more, without additional programming effort. …”
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648por Filippou, Panagiotis Ch., Jeong, Jaewoo, Ferrante, Yari, Yang, See-Hun, Topuria, Teya, Samant, Mahesh G., Parkin, Stuart S. P.“…Excellent perpendicular magnetic anisotropy is found in ferrimagnetic X(3)Z (X = Mn; Z = Ge, Sn, Sb) films, just 1 or 2 unit-cells thick. Racetracks formed from these films sustain current-induced domain wall motion with velocities of more than 120 m s(−1), at current densities up to six times lower than conventional ferromagnetic materials. …”
Publicado 2018
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649“…We characterized a series of events during RecBCD-induced DNA unwinding, including initiation, processive translocation, pausing and backtracking, and revealed an initiation mechanism that involves reversible, ATP-independent DNA unwinding and engagement of the RecB motor. …”
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650por Feng, Siyuan, Liu, Yan, Liang, Wanfei, El-Sayed Ahmed, Mohamed Abd El-Gawad, Zhao, Zihan, Shen, Cong, Roberts, Adam P., Liang, Lujie, Liao, Liya, Zhong, Zhijuan, Guo, Zhaowang, Yang, Yongqiang, Wen, Xin, Chen, Hongtao, Tian, Guo-bao“…Moreover, like Escherichia coli GreA, M. smegmatis GreA exhibits a series of conservative features, and the anti-backtracking activity of C-terminal domain is indispensable for the expression of glgX, a gene was down-regulated in the RNA-seq data. …”
Publicado 2020
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651“…NetNCSP is equipped with two key steps, support calculation and closeness determination. A backtracking strategy is employed to calculate the nonoverlapping support of a pattern on the corresponding Nettree, which reduces the time complexity. …”
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652por Samson, Camille, Legrand, Pierre, Tekpinar, Mustafa, Rozenski, Jef, Abramov, Mikhail, Holliger, Philipp, Pinheiro, Vitor B., Herdewijn, Piet, Delarue, Marc“…One complex with two incorporated HNA nucleotides is surprisingly found in a one nucleotide-backtracked form, which is new for a DNA polymerase. …”
Publicado 2020
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653por Fukudome, Akihito, Singh, Jasleen, Mishra, Vibhor, Reddem, Eswar, Martinez-Marquez, Francisco, Wenzel, Sabine, Yan, Rui, Shiozaki, Momoko, Yu, Zhiheng, Wang, Joseph Che-Yen, Takagi, Yuichiro, Pikaard, Craig S.“…These results suggest a model in which Pol IV arrest and backtracking displaces the RNA 3′ end as the DNA strands reanneal, allowing RDR2 to engage the RNA and synthesize the complementary strand.…”
Publicado 2021
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654por Lokhande, Trupti, Yang, Xining, Xie, Yichun, Cook, Katherine, Liang, Jianyuan, LaBelle, Shannon, Meyers, Cassidy“…The fixed model tool is based on an optimized backtracking algorithm. Our flexible model tool can consider various classroom dimensions, fixtures, and a safe social distance. …”
Publicado 2022
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655“…It is shown that the Ter peak is not due to the presence of a strong origin for RLDR in Ter region; instead RLDR, which is partly inhibited by the backtracking-resistant rpoB*35 mutation, appears to contribute indirectly to Ter over-replication. …”
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656“…After trapping, the native entangled structure emerges by either backtracking to the unfolded state or threading through the already formed but not yet entangled loop. …”
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657por Burjanivova, Tatiana, Madzo, Jozef, Muzikova, Katerina, Meyer, Claus, Schneider, Bjoern, Votava, Felix, Marschalek, Rolf, Stary, Jan, Trka, Jan, Zuna, Jan“…CONCLUSION: In the largest cohort examined so far we used identical approach for the backtracking of non-infant childhood ALL and AML. Our data suggest that either the prenatal origin of AML is less frequent or the load of pre-leukemic cells is significantly lower at birth in AML compared to ALL cases.…”
Publicado 2006
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658“…In this study we present a Lagrangian approach to quantify summer sea ice melt in which multiyear ice (MYI) floes that were surveyed by airborne electromagnetic thickness sounding within Nares Strait during summer were backtracked, using satellite imagery, to a region in close proximity (3–20 km) to spring ice thickness surveys carried out in the Lincoln Sea. …”
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659por Qin, Zixuan, Stapornchaisit, Sorawit, He, Zixun, Yoshimura, Natsue, Koike, Yasuharu“…The CC value results of wrist flexion/extension motion obtained from 10 participants was 0.87–0.92, pronation/supination motion was 0.72–0.95, and hand grip/open motion was 0.75–0.94. We backtracked the fully connected layer weights to create a geometry plot for analyzing the motion pattern to investigate the learning of the proposed model. …”
Publicado 2021
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660“…To efficiently calculate the support, NetNMSP employs the backtracking strategy to obtain a nonoverlapping occurrence from the leftmost leaf to its root with the leftmost parent node method in a Nettree. …”
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