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  1. 226401
    “…Because of its efficacy and safety, letermovir has become the standard of care for primary prophylaxis against CMV during the first 100 days post-transplant. …”
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    922. The Impact of Clinically Significant CMV Infections on Other Viral Infections in the Era of Letermovir Primary Prophylaxis
  2. 226402
    “…Access to newer ART regimens may be slowed by delayed QHP coverage or complex negotiations with manufacturers about formulary inclusion as ART options become more competitive, even if patients are insulated from cost differences. …”
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    870. Coverage, Cost Sharing, and Out-of-Pocket Costs for Single-Tablet HIV Antiretroviral Regimens in Qualified Health Plans in the United States, 2018-2020
  3. 226403
    “…CONCLUSION: Urban neighbourhoods in the GTA had elevated risks of becoming ill with TAIs. However, geographic proximity to a travel clinic was not associated with an area-level risk reduction in TAI, suggesting other barriers to seeking and adhering to pre-travel advice. …”
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    737. Geographic Clustering of Travel-acquired Infections in Ontario, Canada, 2008-2020
  4. 226404
    “…BACKGROUND: Carbapenem-resistant Enterobacterales (CRE) have become endemic and cause significant morbidity and mortality globally. …”
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    178. Endemic Carbapenem Resistance Driven By Clonal and Horizontal Spread of bla(IMP-4) Across Diverse Enterobacterales: Jumping Genes, Promiscuous Plasmids and Killer Clones
  5. 226405
    “…In contrast, anti-N Abs decreased, becoming undetectable in some children by 24wks. These findings add to understanding of the natural history of SARS-CoV-2 immunity in children. * This study was supported by CDC BAA75D301-20-R-67897 DISCLOSURES: Jesse Bloom, PhD, Flagship Labs 77 (Consultant)Moderna (Consultant) Janet A. …”
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    LB9. Longitudinal antibody dynamics in children infected with SARS-CoV-2 through 6 months post-infection
  6. 226406
    “…Proton radiation therapy has become an increasingly common treatment in comparison to photon radiation therapy due to the ability to reduce off-target radiation dose. …”
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    Therapeutic Efficacy of Variable Biological Effectiveness of Proton Therapy in U-CH2 and MUG-Chor1 Human Chordoma Cell Death
  7. 226407
    “…Thus, Nestin-GFP mice (CB-17 background) could become a useful tool with which to investigate the mechanism of neurogenesis via the aforementioned cells under pathological conditions such as following ischemic stroke.…”
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    Establishment of a Reproducible Ischemic Stroke Model in Nestin-GFP Mice with High Survival Rates
  8. 226408
    “…Perturbation Theory Operators (PTOs) with the form of Moving Average (MA) operators have been used to quantify perturbations (deviations) in the structural variables with respect to their expected values for different subsets (partitions) of categorical variables. …”
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    IFPTML Mapping of Drug Graphs with Protein and Chromosome Structural Networks vs. Pre-Clinical Assay Information for Discovery of Antimalarial Compounds
  9. 226409
    “…To improve clinical outcomes while reducing costs and utilization, population health management programs often provide targeted interventions to patients who may become persistent high users/utilizers (PHUs). Enhanced prediction and management of PHUs can improve health care system efficiencies and improve the overall quality of patient care. …”
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    Assessing the Value of Unsupervised Clustering in Predicting Persistent High Health Care Utilizers: Retrospective Analysis of Insurance Claims Data
  10. 226410
    “…In response to this, mental health apps (MHapps) are becoming available for monitoring, managing, and promoting positive mental health and well-being. …”
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    Mobile Apps That Promote Emotion Regulation, Positive Mental Health, and Well-being in the General Population: Systematic Review and Meta-analysis
  11. 226411
    “…BACKGROUND: Behavioral eHealth and mobile health interventions have been moderately successful in increasing physical activity, although opportunities for further improvement remain to be discussed. …”
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    Feasibility, Usability, and Effectiveness of a Machine Learning–Based Physical Activity Chatbot: Quasi-Experimental Study
  12. 226412
    “…Molecular dynamic simulations of the δ-secretase-docked complex have been carried out for a time period of 200 ns and revealed that Root Mean Square Deviation (RMSD) of the protein Cα-backbone with respect to its starting position increased to 1.20 Å for the first 25 ns of the trajectory and then became stable around 0.6 Å in the last 170 ns course of the simulation. …”
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    Network-based identification of miRNAs and transcription factors and in silico drug screening targeting δ-secretase involved in Alzheimer's disease
  13. 226413
    “…BACKGROUND: Mobile health (mHealth) apps are becoming increasingly common in surgical practices for training, education, and communication. …”
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    Mobile Health Apps That Act as Surgical Preparatory Guides: App Store Search and Quality Evaluation
  14. 226414
    “…Program leadership reported that the practice was both feasible and well accepted by residents, faculty, and the APRH chief medical officer as the TOC-CEX became a customary component of APRH organizational culture and was perceived as central to quality patient care.…”
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    Using a Direct Observation Tool (TOC-CEX) to Standardize Transitions of Care by Residents at a Community Hospital
  15. 226415
    “…CATEGORY: Outcomes INTRODUCTION/PURPOSE: Healthcare is at a unique time in history where patient reported outcomes have become important in assessing value and subsequent reimbursement with pay-4-performance initiatives. …”
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    Does Physical Therapy Produce Value for Post-Operative and/or Non-Operative Foot and Ankle Patients?
  16. 226416
    “…More recently, first metatarsophalangeal (MTP) joint hemiarthroplasty with a polyvinyl alcohol (PVA) hydrogel implant (Cartiva) has become a popular surgical option. A randomized clinical trial sponsored by the manufacturers of the implant showed equivalent pain relief and functional outcome scores at 2 year follow-up when compared to patients undergoing first MTP fusion. …”
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    Clinical Outcomes and PROMIS Scores with the Use of Synthetic Cartilage Implant (CARTIVA) in Hallux Rigidus at a Non-Industry Sponsored, Multi-Surgeon, Academic Institution
  17. 226417
    “…CATEGORY: Midfoot/Forefoot INTRODUCTION/PURPOSE: Müller Weiss disease is becoming increasingly recognized and is of unknown etiology. …”
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    Müller Weiss Disease: Radiological Evaluation and Proposed Treatment Algorithm
  18. 226418
    “…CATEGORY: Bunion INTRODUCTION/PURPOSE: The Lapidus procedure is becoming more popular in the surgical correction of hallux valgus deformities. …”
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    Radiographic Outcome Analysis Following A Modified Lapidus with Fusion of the First Intermetatarsal and First Intercuneiform Joints
  19. 226419
    “…Risk adjustment of 90-day costs will become a necessity as bundled-payment models begin to take over the current fee-for-service model in fracture patients.…”
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    Refining Risk-Adjustment of 90-day Costs Following Surgical Fixation of Ankle Fractures: Implications for a Bundled Payment Model
  20. 226420
    “…SIMPLE SUMMARY: Other than DNA damage, it has become clear that ionizing radiation can also induce epigenetic effects. …”
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    Evaluation of Global DNA Methylation and Gene Expression of Izumo1 and Izumo1r in Gonads after High- and Low-Dose Radiation in Neonatal Mice
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