“…Marine natural products have become a source of novel agents that modulate eicosanoids and O(2)(- )generation from activated murine and human leukocytes. …”
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“…Somewhat paradoxically, under this scenario, we surmise that selfish genetic elements ancestral to viruses evolved prior to typical cells, to become intracellular parasites once bacteria and archaea arrived at the scene. …”
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“…BACKGROUND: Mitochondrial DNA (mtDNA) haplotypes have become popular tools for tracing maternal ancestry, and several companies offer this service to the general public. …”
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“…However, patients who have one or more prior vertebral fractures (prevalent at the time of their non-vertebral fracture) would also become candidates for anti-resorptive therapy—which would have not been the case had their vertebral fracture status not been known. …”
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“…Animal foods, in which constituents poisonous to rabbits have developed, probably slightly hasten the onset of the severer symptoms, and the vaunted remarkably modifying influence of a diet of ordinary milk, such as Breisacher observed, does not exist in the case of the totally thyroidless dog. (13) Monkeys whose general metabolism is disturbed in consequence of the removal of a greater portion of the thyroid gland, evidently become more susceptible to those constituents of meat that are poisonous to rabbits, and sufficient clinical evidence exists for concluding that probably a like susceptibility to animal foods containing such constituents also exists in men when the function of the thyroid gland is sufficiently disturbed. (14) And, finally, as regards the thyroid factor in the pathology of exophthalmic goitre, I agree with Gley that the majority of the symptoms in many patients with that disease can apparently, from an experimental standpoint, be as plausibly explained by the hypothesis of partially deficient thyroid activity as by the hypothesis of augmentation of thyroid function.…”
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“…During this time they become emaciated to a marked degree. Then the low septicemia rapidly rises or the rabbit with a sterile culture develops a severe septicemia within a few hours and death takes place from a few hours to two days thereafter. …”
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“…Very soon the mitotic proliferation extends to the tongue and the number of proliferating cells may here become greater than in the old epithelium. With the closure of the wound a sudden fall in the number of mitoses takes place in both series. …”
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“…But the animals which have once received these injections become refractory to a subsequent vaccination as applied to the skin. …”
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“…It may be concluded, therefore, that when a sufficient quantity of killed cultures of Leptospira icterohæmorrhagiæ is given, the guinea pigs will become immune to all strains of the same organism, but that smaller quantities may protect them against homologous but not against heterologous strains. …”
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“…In the early transfers the disease may be fatal, but it usually becomes milder in successive passages. Although we have not yet been able to cultivate Bartonella muris and prove its etiological relationship to rat anemia by inoculation of cultures, we have added to the evidence that Bartonella muris is the cause of the anemia. …”
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“…When this protein film is destroyed by heat-coagulation, the complement-fixing property is lost; concomitantly, the specific groups of the lipoid having been freed from the closely adherent reagin, the antigen becomes again active, able to react with more syphilitic serum. …”
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“…It was found that apparently different concentrations of these chemicals are required to exert this type of protective effect in different hosts or against different viruses, for while mice are readily protected against nasal infection with equine encephalomyelitis virus by 0.5 per cent solutions of tannic acid or alum (7), monkeys require at least 3 per cent solutions to become resistant against poliomyelitis. Experiments designed to elucidate the development of this refractory state in monkeys indicate that it is a result of the action of these chemicals not upon the virus but rather upon the tissues of the host (probably the olfactory mucosa); further evidence in favor of this hypothesis may be found in the observation that several days of treatment are required before resistance is induced. …”
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“…Recently, evidence has been presented that suggests deoxyribonuclease I (DNase I) is identical or very closely related to the apoptotic endonuclease (Peitsch, M.C., B. …”
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“…In concentrations of M/8 or above the influence of the electrical charges of ions mentioned in (b) or (c) seems to become less noticeable or to disappear entirely. 2. …”
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“…The need of calcium to effect ameboid movement has been shown by Pantin (13) in a series of immersion experiments. …”
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“…When a compound enters a living cell until its activity becomes greater inside than outside, it may be said to accumulate. …”
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“…If so these results have an obvious bearing on the movement of water in the organism and on methods of studying permeability. It becomes necessary to know to what extent a substance entering or leaving the cell appears to carry water with it in the manner here indicated. …”
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“…An. stephensi is the most important malaria vector in Asia and it is becoming a model Anopheline species for physiological and genetics studies. …”
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“…Therefore, this microbe has become a prime system for carrying out whole-cell bioreductions at different scales. …”
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“…[Image: see text] Analysis of cellular 7,8-dihydro-8-oxo-2′-deoxyguanosine (8-oxo-dGuo) as a biomarker of oxidative DNA damage has been fraught with numerous methodological problems. …”
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