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227441por Haumann, Johan, Camara, Amadou K. S., Gadicherla, Ashish K., Navarro, Christopher D., Boelens, Age D., Blomeyer, Christoph A., Dash, Ranjan K., Boswell, Michael R., Kwok, Wai-Meng, Stowe, David F.“…The kinetics of slow mCa(2+) efflux with slow H(+) influx via CHE(m) was also observed at pH(e) 6.9 vs. 7.6 by the slow fall in pH(m) until ΔpH(m) was abolished; if Ca(2+) reuptake via the MCU was also blocked, mCa(2+) efflux via CHE(m) became more evident. Of the two components of the proton electrochemical gradient, our results indicate that CHE(m) activity is driven largely by the ΔpH(m) chemical gradient with H(+) leak, while mCa(2+) entry via MCU depends largely on the charge gradient ΔΨ(m). …”
Publicado 2019
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227442por Homsy, Jaco, King, Rachel, Bannink, Femke, Namukwaya, Zikulah, Vittinghof, Eric, Amone, Alexander, Ojok, Francis, Rukundo, Gordon, Amama, Sharon, Etima, Juliane, Matovu, Joyce, Weissglas, Fitti, Ojom, Lawrence, Atim, Pamela, Darbes, Lynae, Byamugisha, Josaphat, Rutherford, George, Katabira, Elly, Fowler, Mary Glenn“…Four women (two in each arm) and no enrolled men became infected with HIV, representing an overall HIV incidence rate of 0.186 per 100 person-years. …”
Publicado 2019
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227443por Wijetunga, Udai, Bulugahapitiya, Uditha, Wijeratne, Thejana, Jayasuriya, Anuradha, Ratnayake, Gowri, Kaluarachchi, Vidumini, Gunatilake, Sonali, Silva, Charini, Gunawardena, Asela“…Obesity and its complications have become a major public health problem. Health risk conferred by obesity can be reduced by sustained weight loss but this is difficult in a majority. …”
Publicado 2019
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227444“…She was pyrexic at night when her skin became inflamed. ESR-35 and CRP-13. RF, anti-CCP, ANA, ANCA, ACE and ASOT titre were negative. …”
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227445“…Given the wealth of data which has been curated in this fashion, there are numerous explicit questions that can be asked of the data. …”
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227446Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity“…Other pathological injuries to striated muscle, spleen, lung, liver and kidney also have been noted. A consistent observation is cardiac myocyte degeneration as well as vacuolization. …”
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227447por Yeh, Hsuan, Lin, Chihung, Li, Yan-Rong, Yen, Chieh-Li, Lee, Cheng-Chia, Chen, Jung-Sheng, Chen, Kuan-Hsing, Tian, Ya-Chun, Liu, Pi-Hua, Hsiao, Ching-Chung“…BACKGROUND: Allograft kidney transplantation has become a treatment of choice for patients with end-stage renal disease (ESRD), and post-transplant diabetes mellitus (PTDM) has been associated with impaired patient and graft survival. …”
Publicado 2020
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227448“…BACKGROUND: Structural retinal architecture in living organisms became measurable with the development of optical coherence tomography (OCT) scanners. …”
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227449por Sullender, Wayne M, Fowler, Karen B, Gupta, Vivek, Krishnan, Anand, Ram Purakayastha, Debjani, Srungaram VLN, Raghuram, Lafond, Kathryn E, Saha, Siddhartha, Palomeque, Francisco S, Gargiullo, Paul, Jain, Seema, Lal, Renu, Widdowson, Marc-Alain, Broor, Shobha“…Clusters were defined as households (ie, dwellings that shared a courtyard), and children aged 6 months to 10 years were eligible for vaccination as and when they became age-eligible throughout the study. Households were randomly assigned (1:1) by a computer-based system to intramuscular trivalent inactivated influenza vaccine (IIV3) or a control of inactivated poliovirus vaccine (IPV) in the beginning of the study; vaccination occurred once a year for 3 years. …”
Publicado 2019
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227450por Liu, Hejing, Li, Qiudan, Zhan, Yongcheng, Zhang, Zhu, Zeng, Daniel D, Leischow, Scott J“…BACKGROUND: Stopping the epidemic of e-cigarette use among youth has become the common goal of both regulatory authorities and health departments. …”
Publicado 2020
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227451por Jani, Meghna, Birlie Yimer, Belay, Sheppard, Therese, Lunt, Mark, Dixon, William G.“…Additionally, physician prescribing behaviour has been described as a key driver of rising opioid prescriptions and long-term opioid use. …”
Publicado 2020
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227452“…Conventional synthetic DMARDs have also been reported efficacious. Biologic DMARDS have been used in resistant cases. …”
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227453por Horn, Abigail L., Jiang, Lai, Washburn, Faith, Hvitfeldt, Emil, de la Haye, Kayla, Nicholas, William, Simon, Paul, Pentz, Maryann, Cozen, Wendy, Sood, Neeraj, Conti, David V.“…While similar numbers of deaths as observed in LAC could have been achieved with a more moderate NPI policy combined with greater protection of individuals 65+, this would have come at the expense of overwhelming the healthcare system. …”
Publicado 2020
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227454por Yuan, Mingcheng, Wang, Yichen, Wang, Haoyang, Ding, Zichuan, Xiao, Qiang, Zhou, Zongke“…The eversion group had a significantly longer LOS (5.61 ± 1.92 vs 4.93 ± 1.45 days [P = 0.044]) and worse HSS score within 2 months PO (3 weeks PO: 77.4 ± 7.6 vs 81.7 ± 7.2 [P = 0.004]; 2 months PO: 85.1 ± 7.2 vs 88.5 ± 6.1 [P = 0.011]), but at the third follow‐up (6 months PO), the HSS score in the two groups became comparable (P > 0.05). No patellar tilt occurred in either group and there was only one case of patellar baja in the eversion group, with no significant between‐group difference (P > 0.05). …”
Publicado 2020
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227455por Plaza-Rodríguez, Carolina, Alt, Katja, Grobbel, Mirjam, Hammerl, Jens Andre, Irrgang, Alexandra, Szabo, Istvan, Stingl, Kerstin, Schuh, Elisabeth, Wiehle, Lars, Pfefferkorn, Beatrice, Naumann, Steffen, Kaesbohrer, Annemarie, Tenhagen, Bernd-Alois“…Furthermore, the possible role of wildlife as reservoir and disperser of resistant bacteria would need to be assessed, as wild animals, and in particular wild ducks and geese could become spreaders of resistant bacteria given their capacity for long-range movements.…”
Publicado 2021
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227456“…These new indicators have also been widely investigated in preeclampsia (PE) but less analyzed in hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome. …”
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227457por Koch, Aleksander, Krasny, Joanna, Dziurda, Magdalena, Ratajczyk, Magdalena, Jozwiak, Marek“…Steroid injections to the hip joint need to be repeated, and with the follow-up time, it becomes less effective. Steroid injection seems to be the treatment of choice for patients with general anesthesia contraindications. …”
Publicado 2021
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227458por Büssing, Arndt, Rodrigues Recchia, Daniela, Dienberg, Thomas, Surzykiewicz, Janusz, Baumann, Klaus“…A previous study with persons recruited in June 2020 directly after the lockdown in Germany showed that the best predictors of these perceived changes related to the Corona pandemic were the ability to mindfully stop and pause in distinct situations, to be “spellbound at the moment” and to become “quiet and devout,” indicating moments of wondering awe, with subsequent feelings of gratitude. …”
Publicado 2021
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227459“…Taken together, these findings suggest that CD28 signaling may facilitate PC fate in COVID-19 pediatric patients and the development of KD arises from broad antibody specificity, possibly explaining how vascular antigens become targets. Furthermore, MIS-C, although similar in symptomatic presentation to KD, has an etiology driven by antigen-independent inflammation arising from immature B cells due to a lack of CD28-mediated PC differentiation and survival, which can be evaluated diagnostically by simple flow cytometry in a vaccination setting. …”
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227460por Roberti, Maria do Rosario Ferraz, Prudente, Tiago Paiva, Castro, Renato Gomes, Candido, Marcos Antonio, Rodrigues, Roberta Luiza, Morelli, Maria Cunha Ribeiro, Gonçalves, Alexandra Vilela, de Sá, Jaciane Soares, de Souza, Layane Marques, Rabahi, Marcelo Fouad, Arantes, Adriano de Moraes“…In conclusion, the COVID-19 pandemic has become a public health challenge worldwide. Many recovered patients could donate CP. …”
Publicado 2020
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