Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England, 16 November to 5 February

por Grint, Daniel J, Wing, Kevin, Williamson, Elizabeth, McDonald, Helen I, Bhaskaran, Krishnan, Evans, David, Evans, Stephen JW, Walker, Alex J, Hickman, George, Nightingale, Emily, Schultze, Anna, Rentsch, Christopher T, Bates, Chris, Cockburn, Jonathan, Curtis, Helen J, Morton, Caroline E, Bacon, Sebastian, Davy, Simon, Wong, Angel YS, Mehrkar, Amir, Tomlinson, Laurie, Douglas, Ian J, Mathur, Rohini, Blomquist, Paula, MacKenna, Brian, Ingelsby, Peter, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, DeVito, Nicholas J, Hulme, Will, Tazare, John, Goldacre, Ben, Smeeth, Liam, Eggo, Rosalind M
Publicado 2021

Risks of covid-19 hospital admission and death for people with learning disability: population based cohort study using the OpenSAFELY platform

por Williamson, Elizabeth J, McDonald, Helen I, Bhaskaran, Krishnan, Walker, Alex J, Bacon, Sebastian, Davy, Simon, Schultze, Anna, Tomlinson, Laurie, Bates, Chris, Ramsay, Mary, Curtis, Helen J, Forbes, Harriet, Wing, Kevin, Minassian, Caroline, Tazare, John, Morton, Caroline E, Nightingale, Emily, Mehrkar, Amir, Evans, Dave, Inglesby, Peter, MacKenna, Brian, Cockburn, Jonathan, Rentsch, Christopher T, Mathur, Rohini, Wong, Angel Y S, Eggo, Rosalind M, Hulme, William, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, Douglas, Ian J, Evans, Stephen J W, Smeeth, Liam, Goldacre, Ben, Kuper, Hannah
Publicado 2021

Describing the population experiencing COVID-19 vaccine breakthrough following second vaccination in England: a cohort study from OpenSAFELY

por Green, Amelia, Curtis, Helen, Hulme, William, Williamson, Elizabeth, McDonald, Helen, Bhaskaran, Krishnan, Rentsch, Christopher, Schultze, Anna, MacKenna, Brian, Mahalingasivam, Viyaasan, Tomlinson, Laurie, Walker, Alex, Fisher, Louis, Massey, Jon, Andrews, Colm, Hopcroft, Lisa, Morton, Caroline, Croker, Richard, Morley, Jessica, Mehrkar, Amir, Bacon, Seb, Evans, David, Inglesby, Peter, Hickman, George, Ward, Tom, Davy, Simon, Mathur, Rohini, Tazare, John, Eggo, Rosalind, Wing, Kevin, Wong, Angel, Forbes, Harriet, Bates, Chris, Cockburn, Jonathan, Parry, John, Hester, Frank, Harper, Sam, Douglas, Ian, Evans, Stephen, Smeeth, Liam, Goldacre, Ben
Publicado 2022

Recording of ’COVID-19 vaccine declined‘: a cohort study on 57.9 million National Health Service patients’ records in situ using OpenSAFELY, England, 8 December 2020 to 25 May 2021...

por Curtis, Helen J, Inglesby, Peter, MacKenna, Brian, Croker, Richard, Hulme, William J, Rentsch, Christopher T, Bhaskaran, Krishnan, Mathur, Rohini, Morton, Caroline E, Bacon, Sebastian CJ, Smith, Rebecca M, Evans, David, Mehrkar, Amir, Tomlinson, Laurie, Walker, Alex J, Bates, Christopher, Hickman, George, Ward, Tom, Morley, Jessica, Cockburn, Jonathan, Davy, Simon, Williamson, Elizabeth J, Eggo, Rosalind M, Parry, John, Hester, Frank, Harper, Sam, O’Hanlon, Shaun, Eavis, Alex, Jarvis, Richard, Avramov, Dima, Griffiths, Paul, Fowles, Aaron, Parkes, Nasreen, Evans, Stephen JW, Douglas, Ian J, Smeeth, Liam, Goldacre, Ben
Publicado 2022

Comparative effectiveness of sotrovimab and molnupiravir for prevention of severe covid-19 outcomes in patients in the community: observational cohort study with the OpenSAFELY pla...

por Zheng, Bang, Green, Amelia C A, Tazare, John, Curtis, Helen J, Fisher, Louis, Nab, Linda, Schultze, Anna, Mahalingasivam, Viyaasan, Parker, Edward P K, Hulme, William J, Bacon, Sebastian C J, DeVito, Nicholas J, Bates, Christopher, Evans, David, Inglesby, Peter, Drysdale, Henry, Davy, Simon, Cockburn, Jonathan, Morton, Caroline E, Hickman, George, Ward, Tom, Smith, Rebecca M, Parry, John, Hester, Frank, Harper, Sam, Mehrkar, Amir, Eggo, Rosalind M, Walker, Alex J, Evans, Stephen J W, Douglas, Ian J, MacKenna, Brian, Goldacre, Ben, Tomlinson, Laurie A
Publicado 2022

Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells

por Halbrook, Christopher J., Thurston, Galloway, Boyer, Seth, Anaraki, Cecily, Jiménez, Jennifer A., McCarthy, Amy, Steele, Nina G., Kerk, Samuel A., Hong, Hanna S., Lin, Lin, Law, Fiona V., Felton, Catherine, Scipioni, Lorenzo, Sajjakulnukit, Peter, Andren, Anthony, Beutel, Alica K., Singh, Rima, Nelson, Barbara S., Van Den Bergh, Fran, Krall, Abigail S., Mullen, Peter J., Zhang, Li, Batra, Sandeep, Morton, Jennifer P., Stanger, Ben Z., Christofk, Heather R., Digman, Michelle A., Beard, Daniel A., Viale, Andrea, Zhang, Ji, Crawford, Howard C., Pasca di Magliano, Marina, Jorgensen, Claus, Lyssiotis, Costas A.
Publicado 2022

Rates of serious clinical outcomes in survivors of hospitalisation with COVID-19 in England: a descriptive cohort study within the OpenSAFELY platform

por Tazare, John, Walker, Alex J., Tomlinson, Laurie A., Hickman, George, Rentsch, Christopher T., Williamson, Elizabeth J., Bhaskaran, Krishnan, Evans, David, Wing, Kevin, Mathur, Rohini, Wong, Angel YS., Schultze, Anna, Bacon, Seb, Bates, Chris, Morton, Caroline E., Curtis, Helen J., Nightingale, Emily, McDonald, Helen I., Mehrkar, Amir, Inglesby, Peter, Davy, Simon, MacKenna, Brian, Cockburn, Jonathan, Hulme, William J., Warren-Gash, Charlotte, Bhate, Ketaki, Nitsch, Dorothea, Powell, Emma, Mulick, Amy, Forbes, Harriet, Minassian, Caroline, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, Eggo, Rosalind M., Evans, Stephen JW., Smeeth, Liam, Douglas, Ian J, Goldacre, Ben
Publicado 2022

Association between living with children and outcomes from covid-19: OpenSAFELY cohort study of 12 million adults in England

por Forbes, Harriet, Morton, Caroline E, Bacon, Seb, McDonald, Helen I, Minassian, Caroline, Brown, Jeremy P, Rentsch, Christopher T, Mathur, Rohini, Schultze, Anna, DeVito, Nicholas J, MacKenna, Brian, Hulme, William J, Croker, Richard, Walker, Alex J, Williamson, Elizabeth J, Bates, Chris, Mehrkar, Amir, Curtis, Helen J, Evans, David, Wing, Kevin, Inglesby, Peter, Drysdale, Henry, Wong, Angel Y S, Cockburn, Jonathan, McManus, Robert, Parry, John, Hester, Frank, Harper, Sam, Douglas, Ian J, Smeeth, Liam, Evans, Stephen J W, Bhaskaran, Krishnan, Eggo, Rosalind M, Goldacre, Ben, Tomlinson, Laurie A
Publicado 2021

Ethnic differences in SARS-CoV-2 infection and COVID-19-related hospitalisation, intensive care unit admission, and death in 17 million adults in England: an observational cohort s...

por Mathur, Rohini, Rentsch, Christopher T, Morton, Caroline E, Hulme, William J, Schultze, Anna, MacKenna, Brian, Eggo, Rosalind M, Bhaskaran, Krishnan, Wong, Angel Y S, Williamson, Elizabeth J, Forbes, Harriet, Wing, Kevin, McDonald, Helen I, Bates, Chris, Bacon, Seb, Walker, Alex J, Evans, David, Inglesby, Peter, Mehrkar, Amir, Curtis, Helen J, DeVito, Nicholas J, Croker, Richard, Drysdale, Henry, Cockburn, Jonathan, Parry, John, Hester, Frank, Harper, Sam, Douglas, Ian J, Tomlinson, Laurie, Evans, Stephen J W, Grieve, Richard, Harrison, David, Rowan, Kathy, Khunti, Kamlesh, Chaturvedi, Nishi, Smeeth, Liam, Goldacre, Ben
Publicado 2021

Identifying Care Home Residents in Electronic Health Records - An OpenSAFELY Short Data Report

por Schultze, Anna, Bates, Chris, Cockburn, Jonathan, MacKenna, Brian, Nightingale, Emily, Curtis, Helen J, Hulme, William J, Morton, Caroline E, Croker, Richard, Bacon, Seb, McDonald, Helen I, Rentsch, Christopher T, Bhaskaran, Krishnan, Mathur, Rohini, Tomlinson, Laurie A, Williamson, Elizabeth J, Forbes, Harriet, Tazare, John, Grint, Daniel J, Walker, Alex J, Inglesby, Peter, DeVito, Nicholas J, Mehrkar, Amir, Hickman, George, Davy, Simon, Ward, Tom, Fisher, Louis, Evans, David, Wing, Kevin, Wong, Angel YS, McManus, Robert, Parry, John, Hester, Frank, Harper, Sam, Evans, Stephen JW, Douglas, Ian J, Smeeth, Liam, Eggo, Rosalind M, Goldacre, Ben
Publicado 2021

Severity of Severe Acute Respiratory System Coronavirus 2 (SARS-CoV-2) Alpha Variant (B.1.1.7) in England

por Grint, Daniel J, Wing, Kevin, Houlihan, Catherine, Gibbs, Hamish P, Evans, Stephen J W, Williamson, Elizabeth, McDonald, Helen I, Bhaskaran, Krishnan, Evans, David, Walker, Alex J, Hickman, George, Nightingale, Emily, Schultze, Anna, Rentsch, Christopher T, Bates, Chris, Cockburn, Jonathan, Curtis, Helen J, Morton, Caroline E, Bacon, Sebastian, Davy, Simon, Wong, Angel Y S, Mehrkar, Amir, Tomlinson, Laurie, Douglas, Ian J, Mathur, Rohini, MacKenna, Brian, Ingelsby, Peter, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, DeVito, Nicholas J, Hulme, Will, Tazare, John, Smeeth, Liam, Goldacre, Ben, Eggo, Rosalind M
Publicado 2021

Safety of COVID-19 vaccination and acute neurological events: A self-controlled case series in England using the OpenSAFELY platform

por Walker, Jemma L, Schultze, Anna, Tazare, John, Tamborska, Arina, Singh, Bhagteshwar, Donegan, Katherine, Stowe, Julia, Morton, Caroline E, Hulme, William J, Curtis, Helen J, Williamson, Elizabeth J, Mehrkar, Amir, Eggo, Rosalind M, Rentsch, Christopher T, Mathur, Rohini, Bacon, Sebastian, Walker, Alex J, Davy, Simon, Evans, David, Inglesby, Peter, Hickman, George, MacKenna, Brian, Tomlinson, Laurie, CA Green, Amelia, Fisher, Louis, Cockburn, Jonathan, Parry, John, Hester, Frank, Harper, Sam, Bates, Christopher, Evans, Stephen JW, Solomon, Tom, Andrews, Nick J, Douglas, Ian J, Goldacre, Ben, Smeeth, Liam, McDonald, Helen I
Publicado 2022

Eleven key measures for monitoring general practice clinical activity during COVID-19: A retrospective cohort study using 48 million adults’ primary care records in England through...

por Fisher, Louis, Curtis, Helen J, Croker, Richard, Wiedemann, Milan, Speed, Victoria, Wood, Christopher, Brown, Andrew, Hopcroft, Lisa EM, Higgins, Rose, Massey, Jon, Inglesby, Peter, Morton, Caroline E, Walker, Alex J, Morley, Jessica, Mehrkar, Amir, Bacon, Seb, Hickman, George, Macdonald, Orla, Lewis, Tom, Wood, Marion, Myers, Martin, Samuel, Miriam, Conibere, Robin, Baqir, Wasim, Sood, Harpreet, Drury, Charles, Collison, Kiren, Bates, Chris, Evans, David, Dillingham, Iain, Ward, Tom, Davy, Simon, Smith, Rebecca M, Hulme, William, Green, Amelia, Parry, John, Hester, Frank, Harper, Sam, Cockburn, Jonathan, O'Hanlon, Shaun, Eavis, Alex, Jarvis, Richard, Avramov, Dima, Griffiths, Paul, Fowles, Aaron, Parkes, Nasreen, MacKenna, Brian, Goldacre, Ben
Publicado 2023

Clinical coding of long COVID in English primary care: a federated analysis of 58 million patient records in situ using OpenSAFELY

por Walker, Alex J, MacKenna, Brian, Inglesby, Peter, Tomlinson, Laurie, Rentsch, Christopher T, Curtis, Helen J, Morton, Caroline E, Morley, Jessica, Mehrkar, Amir, Bacon, Seb, Hickman, George, Bates, Chris, Croker, Richard, Evans, David, Ward, Tom, Cockburn, Jonathan, Davy, Simon, Bhaskaran, Krishnan, Schultze, Anna, Williamson, Elizabeth J, Hulme, William J, McDonald, Helen I, Mathur, Rohini, Eggo, Rosalind M, Wing, Kevin, Wong, Angel YS, Forbes, Harriet, Tazare, John, Parry, John, Hester, Frank, Harper, Sam, O’Hanlon, Shaun, Eavis, Alex, Jarvis, Richard, Avramov, Dima, Griffiths, Paul, Fowles, Aaron, Parkes, Nasreen, Douglas, Ian J, Evans, Stephen JW, Smeeth, Liam, Goldacre, Ben
Publicado 2021

Trends and clinical characteristics of COVID-19 vaccine recipients: a federated analysis of 57.9 million patients' primary care records in situ using OpenSAFELY

por Curtis, Helen J, Inglesby, Peter, Morton, Caroline E, MacKenna, Brian, Green, Amelia, Hulme, William, Walker, Alex J, Morley, Jessica, Mehrkar, Amir, Bacon, Seb, Hickman, George, Bates, Chris, Croker, Richard, Evans, David, Ward, Tom, Cockburn, Jonathan, Davy, Simon, Bhaskaran, Krishnan, Schultze, Anna, Rentsch, Christopher T, Williamson, Elizabeth J, Rowan, Anna, Fisher, Louis, McDonald, Helen I, Tomlinson, Laurie, Mathur, Rohini, Drysdale, Henry, Eggo, Rosalind M, Wing, Kevin, Wong, Angel YS, Forbes, Harriet, Parry, John, Hester, Frank, Harper, Sam, O’Hanlon, Shaun, Eavis, Alex, Jarvis, Richard, Avramov, Dima, Griffiths, Paul, Fowles, Aaron, Parkes, Nasreen, Douglas, Ian J, Evans, Stephen JW, Smeeth, Liam, Goldacre, Ben
Publicado 2021

Mortality among Care Home Residents in England during the first and second waves of the COVID-19 pandemic: an observational study of 4.3 million adults over the age of 65

por Schultze, Anna, Nightingale, Emily, Evans, David, Hulme, William, Rosello, Alicia, Bates, Chris, Cockburn, Jonathan, MacKenna, Brian, Curtis, Helen J, Morton, Caroline E, Croker, Richard, Bacon, Seb, McDonald, Helen I, Rentsch, Christopher T, Bhaskaran, Krishnan, Mathur, Rohini, Tomlinson, Laurie A, Williamson, Elizabeth J, Forbes, Harriet, Tazare, John, Grint, Daniel, Walker, Alex J, Inglesby, Peter, DeVito, Nicholas J, Mehrkar, Amir, Hickman, George, Davy, Simon, Ward, Tom, Fisher, Louis, Green, Amelia CA, Wing, Kevin, Wong, Angel YS, McManus, Robert, Parry, John, Hester, Frank, Harper, Sam, Evans, Stephen JW, Douglas, Ian J, Smeeth, Liam, Eggo, Rosalind M, Goldacre, Ben, Leon, David A
Publicado 2022

Comparison of methods for predicting COVID-19-related death in the general population using the OpenSAFELY platform

por Williamson, Elizabeth J., Tazare, John, Bhaskaran, Krishnan, McDonald, Helen I., Walker, Alex J., Tomlinson, Laurie, Wing, Kevin, Bacon, Sebastian, Bates, Chris, Curtis, Helen J., Forbes, Harriet J., Minassian, Caroline, Morton, Caroline E., Nightingale, Emily, Mehrkar, Amir, Evans, David, Nicholson, Brian D., Leon, David A., Inglesby, Peter, MacKenna, Brian, Davies, Nicholas G., DeVito, Nicholas J., Drysdale, Henry, Cockburn, Jonathan, Hulme, William J., Morley, Jessica, Douglas, Ian, Rentsch, Christopher T., Mathur, Rohini, Wong, Angel, Schultze, Anna, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, Grieve, Richard, Harrison, David A., Steyerberg, Ewout W., Eggo, Rosalind M., Diaz-Ordaz, Karla, Keogh, Ruth, Evans, Stephen J. W., Smeeth, Liam, Goldacre, Ben
Publicado 2022

A comprehensive high cost drugs dataset from the NHS in England - An OpenSAFELY-TPP Short Data Report

por Rowan, Anna, Bates, Chris, Hulme, William, Evans, David, Davy, Simon, A Kennedy, Nicholas, Galloway, James, E Mansfield, Kathryn, Bechman, Katie, Matthewman, Julian, Yates, Mark, Brown, Jeremy, Schultze, Anna, Norton, Sam, J. Walker, Alex, E. Morton, Caroline, Bhaskaran, Krishnan, T. Rentsch, Christopher, Williamson, Elizabeth, Croker, Richard, Bacon, Seb, Hickman, George, Ward, Tom, Green, Amelia, Fisher, Louis, J Curtis, Helen, Tazare, John, M. Eggo, Rosalind, Inglesby, Peter, Cockburn, Jonathan, I. McDonald, Helen, Mathur, Rohini, YS Wong, Angel, Forbes, Harriet, Parry, John, Hester, Frank, Harper, Sam, J Douglas, Ian, Smeeth, Liam, A Tomlinson, Laurie, W Lees, Charlie, Evans, Stephen, Smith, Catherine, M. Langan, Sinéad, Mehkar, Amir, MacKenna, Brian, Goldacre, Ben
Publicado 2021

Comparative effectiveness of ChAdOx1 versus BNT162b2 covid-19 vaccines in health and social care workers in England: cohort study using OpenSAFELY

por Hulme, William J, Williamson, Elizabeth J, Green, Amelia C A, Bhaskaran, Krishnan, McDonald, Helen I, Rentsch, Christopher T, Schultze, Anna, Tazare, John, Curtis, Helen J, Walker, Alex J, Tomlinson, Laurie A, Palmer, Tom, Horne, Elsie M F, MacKenna, Brian, Morton, Caroline E, Mehrkar, Amir, Morley, Jessica, Fisher, Louis, Bacon, Sebastian C J, Evans, David, Inglesby, Peter, Hickman, George, Davy, Simon, Ward, Tom, Croker, Richard, Eggo, Rosalind M, Wong, Angel Y S, Mathur, Rohini, Wing, Kevin, Forbes, Harriet, Grint, Daniel J, Douglas, Ian J, Evans, Stephen J W, Smeeth, Liam, Bates, Chris, Cockburn, Jonathan, Parry, John, Hester, Frank, Harper, Sam, Sterne, Jonathan A C, Hernán, Miguel A, Goldacre, Ben
Publicado 2022

Trends, variation, and clinical characteristics of recipients of antiviral drugs and neutralising monoclonal antibodies for covid-19 in community settings: retrospective, descripti...

por Green, Amelia C A, Curtis, Helen J, Higgins, Rose, Nab, Linda, Mahalingasivam, Viyaasan, Smith, Rebecca M, Mehrkar, Amir, Inglesby, Peter, Drysdale, Henry, DeVito, Nicholas J, Croker, Richard, Rentsch, Christopher T, Bhaskaran, Krishnan, Tazare, John, Zheng, Bang, Andrews, Colm D, Bacon, Sebastian C J, Davy, Simon, Dillingham, Iain, Evans, David, Fisher, Louis, Hickman, George, Hopcroft, Lisa E M, Hulme, William J, Massey, Jon, MacDonald, Orla, Morley, Jessica, Morton, Caroline E, Park, Robin Y, Walker, Alex J, Ward, Tom, Wiedemann, Milan, Bates, Christopher, Cockburn, Jonathan, Parry, John, Hester, Frank, Harper, Sam, Douglas, Ian J, Evans, Stephen J W, Goldacre, Ben, Tomlinson, Laurie A, MacKenna, Brian
Publicado 2023