Molecular rationale for the impairment of the MexAB-OprM efflux pump by a single mutation in MexA

por Cacciotto, Pierpaolo, Basciu, Andrea, Oliva, Francesco, Malloci, Giuliano, Zacharias, Martin, Ruggerone, Paolo, Vargiu, Attilio V.
Publicado 2021

Dynorphin A induces membrane permeabilization by formation of proteolipidic pores. Insights from electrophysiology and computational simulations

por Perini, D. Aurora, Aguilella-Arzo, Marcel, Alcaraz, Antonio, Perálvarez-Marín, Alex, Queralt-Martín, María
Publicado 2021

miR-4759 suppresses breast cancer through immune checkpoint blockade

por Lin, You-Zhe, Liu, Shu-Hsuan, Wu, Wan-Rong, Shen, Yi-Chun, Wang, Yuan-Liang, Liao, Chien-Ching, Lin, Pei-Le, Chang, Han, Liu, Liang-Chih, Cheng, Wei-Chung, Wang, Shao-Chun
Publicado 2021

Flow cytometry-based study of model marine microalgal consortia revealed an ecological advantage of siderophore utilization by the dinoflagellate Amphidinium carterae

por Malych, Ronald, Stopka, Pavel, Mach, Jan, Kotabová, Eva, Prášil, Ondřej, Sutak, Robert
Publicado 2021

Inferring early-life host and microbiome functions by mass spectrometry-based metaproteomics and metabolomics

por Pettersen, Veronika Kuchařová, Antunes, Luis Caetano Martha, Dufour, Antoine, Arrieta, Marie-Claire
Publicado 2021

Key reaction components affect the kinetics and performance robustness of cell-free protein synthesis reactions

por Banks, Alice M., Whitfield, Colette J., Brown, Steven R., Fulton, David A., Goodchild, Sarah A., Grant, Christopher, Love, John, Lendrem, Dennis W., Fieldsend, Jonathan E., Howard, Thomas P.
Publicado 2021

regCNN: identifying Drosophila genome-wide cis-regulatory modules via integrating the local patterns in epigenetic marks and transcription factor binding motifs

por Yang, Tzu-Hsien, Yang, Ya-Chiao, Tu, Kai-Chi
Publicado 2021

LncRNA functional annotation with improved false discovery rate achieved by disease associations

por Wang, Yongheng, Zhai, Jincheng, Wu, Xianglu, Adu-Gyamfi, Enoch Appiah, Yang, Lingping, Liu, Taihang, Wang, Meijiao, Ding, Yubin, Zhu, Feng, Wang, Yingxiong, Tang, Jing
Publicado 2021

The natural product biosynthesis potential of the microbiomes of Earth – Bioprospecting for novel anti-microbial agents in the meta-omics era

por Geers, Aileen Ute, Buijs, Yannick, Strube, Mikael Lenz, Gram, Lone, Bentzon-Tilia, Mikkel
Publicado 2021

Prediction of HER2-positive breast cancer recurrence and metastasis risk from histopathological images and clinical information via multimodal deep learning

por Yang, Jialiang, Ju, Jie, Guo, Lei, Ji, Binbin, Shi, Shufang, Yang, Zixuan, Gao, Songlin, Yuan, Xu, Tian, Geng, Liang, Yuebin, Yuan, Peng
Publicado 2021

Epigenomic signatures on paralogous genes reveal underappreciated universality of active histone codes adopted across animals

por Lan, Kuei-Yuan, Liao, Ben-Yang
Publicado 2021

Homologous cardiac calcium pump regulators phospholamban and sarcolipin adopt distinct oligomeric states in the membrane

por Liu, Andy Y., Aguayo-Ortiz, Rodrigo, Guerrero-Serna, Guadalupe, Wang, Nulang, Blin, Muriel G., Goldstein, Daniel R., Michel Espinoza-Fonseca, L.
Publicado 2021

An allosteric regulation mechanism of Arabidopsis Serine/Threonine kinase 1 (SIK1) through phosphorylation

por Mu, Junxi, Zhou, Jiali, Gong, Qingqiu, Xu, Qin
Publicado 2021

Exploring the universal healthy human gut microbiota around the World

por Piquer-Esteban, Samuel, Ruiz-Ruiz, Susana, Arnau, Vicente, Diaz, Wladimiro, Moya, Andrés
Publicado 2021

Critical assessment of structure-based approaches to improve protein resistance in aqueous ionic liquids by enzyme-wide saturation mutagenesis

por El Harrar, Till, Davari, Mehdi D., Jaeger, Karl-Erich, Schwaneberg, Ulrich, Gohlke, Holger
Publicado 2021

Non-monotonic fibril surface occlusion by GFP tags from coarse-grained molecular simulations

por Shillcock, Julian C., Hastings, Janna, Riguet, Nathan, Lashuel, Hilal A.
Publicado 2021

Advanced biokinetic and hydrodynamic modelling to support and optimize the design of full-scale high rate algal ponds

por Ortiz, Antonio, Díez-Montero, Rubén, García, Joan, Khalil, Nadeem, Uggetti, Enrica
Publicado 2021

Probing the formation, structure and free energy relationships of M protein dimers of SARS-CoV-2

por Cao, Yipeng, Yang, Rui, Wang, Wei, Jiang, Shengpeng, Yang, Chengwen, Liu, Ningbo, Dai, Hongji, Lee, Imshik, Meng, Xiangfei, Yuan, Zhiyong
Publicado 2022

Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death

por Margreiter, Michael A, Witzenberger, Monika, Wasser, Yasmine, Davydova, Elena, Janowski, Robert, Metz, Jonas, Habib, Pardes, Sahnoun, Sabri E.M., Sobisch, Carina, Poma, Benedetta, Palomino-Hernandez, Oscar, Wagner, Mirko, Carell, Thomas, Jon Shah, N., Schulz, Jörg B., Niessing, Dierk, Voigt, Aaron, Rossetti, Giulia
Publicado 2021

Using metagenomic data to boost protein structure prediction and discovery

por Hou, Qingzhen, Pucci, Fabrizio, Pan, Fengming, Xue, Fuzhong, Rooman, Marianne, Feng, Qiang
Publicado 2022