Comparative metabolomics revealed key pathways associated with the synergistic killing of multidrug-resistant Klebsiella pneumoniae by a bacteriophage-polymyxin combination

por Han, Mei-Ling, Nang, Sue C., Lin, Yu-Wei, Zhu, Yan, Yu, Heidi H., Wickremasinghe, Hasini, Barlow, Christopher K., Creek, Darren J., Crawford, Simon, Rao, Gauri, Dai, Chongshan, Barr, Jeremy J., Chan, Kim, Turner Schooley, Robert, Velkov, Tony, Li, Jian
Publicado 2022

Addressing the clinical unmet needs in primary Sjögren’s Syndrome through the sharing, harmonization and federated analysis of 21 European cohorts

por Pezoulas, Vasileios C., Goules, Andreas, Kalatzis, Fanis, Chatzis, Luke, Kourou, Konstantina D., Venetsanopoulou, Aliki, Exarchos, Themis P., Gandolfo, Saviana, Votis, Konstantinos, Zampeli, Evi, Burmeister, Jan, May, Thorsten, Marcelino Pérez, Manuel, Lishchuk, Iryna, Chondrogiannis, Thymios, Andronikou, Vassiliki, Varvarigou, Theodora, Filipovic, Nenad, Tsiknakis, Manolis, Baldini, Chiara, Bombardieri, Michele, Bootsma, Hendrika, Bowman, Simon J., Soyfoo, Muhammad Shahnawaz, Parisis, Dorian, Delporte, Christine, Devauchelle-Pensec, Valérie, Pers, Jacques-Olivier, Dörner, Thomas, Bartoloni, Elena, Gerli, Roberto, Giacomelli, Roberto, Jonsson, Roland, Ng, Wan-Fai, Priori, Roberta, Ramos-Casals, Manuel, Sivils, Kathy, Skopouli, Fotini, Torsten, Witte, A. G. van Roon, Joel, Xavier, Mariette, De Vita, Salvatore, Tzioufas, Athanasios G., Fotiadis, Dimitrios I.
Publicado 2022

Computational design of a cutinase for plastic biodegradation by mining molecular dynamics simulations trajectories

por Li, Qingbin, Zheng, Yi, Su, Tianyuan, Wang, Qian, Liang, Quanfeng, Zhang, Ziding, Qi, Qingsheng, Tian, Jian
Publicado 2022

Violations of proportional hazard assumption in Cox regression model of transcriptomic data in TCGA pan-cancer cohorts

por Zeng, Zihang, Gao, Yanping, Li, Jiali, Zhang, Gong, Sun, Shaoxing, Wu, Qiuji, Gong, Yan, Xie, Conghua
Publicado 2022

Richness estimation in microbiome data obtained from denoising pipelines

por Kleine Bardenhorst, Sven, Vital, Marius, Karch, André, Rübsamen, Nicole
Publicado 2022

Random survival forest model identifies novel biomarkers of event-free survival in high-risk pediatric acute lymphoblastic leukemia

por Bohannan, Zachary S., Coffman, Frederick, Mitrofanova, Antonina
Publicado 2022

Evidence of a SARS-CoV-2 double Spike mutation D614G/S939F potentially affecting immune response of infected subjects

por Donzelli, Sara, Spinella, Francesca, di Domenico, Enea Gino, Pontone, Martina, Cavallo, Ilaria, Orlandi, Giulia, Iannazzo, Stefania, Ricciuto, Giulio Maria, ISG Virology Covid Team, Pellini, Raul, Muti, Paola, Strano, Sabrina, Ciliberto, Gennaro, Ensoli, Fabrizio, Zapperi, Stefano, La Porta, Caterina A.M., Blandino, Giovanni, Morrone, Aldo, Pimpinelli, Fulvia
Publicado 2022

Analyzing the human gut mycobiome – A short guide for beginners

por Thielemann, Nadja, Herz, Michaela, Kurzai, Oliver, Martin, Ronny
Publicado 2022

Systems scale characterization of circadian rhythm pathway in Camellia sinensis

por Singh, Gagandeep, Singh, Vikram, Singh, Vikram
Publicado 2022

Montelukast is a dual-purpose inhibitor of SARS-CoV-2 infection and virus-induced IL-6 expression identified by structure-based drug repurposing

por Luedemann, Max, Stadler, Daniela, Cheng, Cho-Chin, Protzer, Ulrike, Knolle, Percy A., Donakonda, Sainitin
Publicado 2022

PSNtools for standalone and web-based structure network analyses of conformational ensembles

por Felline, Angelo, Seeber, Michele, Fanelli, Francesca
Publicado 2022

Delineating the activation mechanism and conformational landscape of a class B G protein-coupled receptor glucagon receptor

por Wang, Ying, Li, Mingyu, Liang, Wenqi, Shi, Xinchao, Fan, Jigang, Kong, Ren, Liu, Yaqin, Zhang, Jian, Chen, Ting, Lu, Shaoyong
Publicado 2022

The emerging potential of microbiome transplantation on human health interventions

por Junca, Howard, Pieper, Dietmar H., Medina, Eva
Publicado 2022

Advances in the development of therapeutic strategies against COVID-19 and perspectives in the drug design for emerging SARS-CoV-2 variants

por Yin, Jialing, Li, Chengcheng, Ye, Chunhong, Ruan, Zhihui, Liang, Yicong, Li, Yongkui, Wu, Jianguo, Luo, Zhen
Publicado 2022

D155Y substitution of SARS-CoV-2 ORF3a weakens binding with Caveolin-1

por Gupta, Suchetana, Mallick, Ditipriya, Banerjee, Kumarjeet, Mukherjee, Shrimon, Sarkar, Soumyadev, Lee, Sonny TM, Basuchowdhuri, Partha, Jana, Siddhartha S
Publicado 2022

The mosquito microbiome includes habitat-specific but rare symbionts

por Schrieke, Hans, Maignien, Loïs, Constancias, Florentin, Trigodet, Florian, Chakloute, Sarah, Rakotoarivony, Ignace, Marie, Albane, L'Ambert, Gregory, Makoundou, Patrick, Pages, Nonito, Murat Eren, A., Weill, Mylène, Sicard, Mathieu, Reveillaud, Julie
Publicado 2021

POT1-TPP1 binding stabilizes POT1, promoting efficient telomere maintenance

por Aramburu, Tomas, Kelich, Joseph, Rice, Cory, Skordalakes, Emmanuel
Publicado 2022

Molecular interaction mechanisms of glycol chitosan self-healing hydrogel as a drug delivery system for gemcitabine and doxorubicin

por Huang, Tzu-Hsuan, Hsu, Shan-hui, Chang, Shu-Wei
Publicado 2022

Effective use of sequence information to predict CRISPR-Cas9 off-target

por Zhang, Zhong-Rui, Jiang, Zhen-Ran
Publicado 2022

Computational analysis and prediction of PE_PGRS proteins using machine learning

por Li, Fuyi, Guo, Xudong, Xiang, Dongxu, Pitt, Miranda E., Bainomugisa, Arnold, Coin, Lachlan J.M.
Publicado 2022