Identification of novel SARS-CoV-2 RNA dependent RNA polymerase (RdRp) inhibitors: From in silico screening to experimentally validated inhibitory activity

por Uengwetwanit, Tanaporn, Chutiwitoonchai, Nopporn, Wichapong, Kanin, Karoonuthaisiri, Nitsara
Publicado 2022

Functional convergence of Yunnan snub-nosed monkey and bamboo-eating panda gut microbiomes revealing the driving by dietary flexibility on mammal gut microbiome

por Xia, Wancai, Liu, Guoqi, Wang, Dali, Chen, Hua, Zhu, Lifeng, Li, Dayong
Publicado 2022

Structural insights into apoptotic regulation of human Bfk as a novel Bcl-2 family member

por Jang, Dong Man, Oh, Eun Kyung, Hahn, Hyunggu, Kim, Hyoun Sook, Han, Byung Woo
Publicado 2022

Predicting the capsid architecture of phages from metagenomic data

por Lee, Diana Y., Bartels, Caitlin, McNair, Katelyn, Edwards, Robert A., Swairjo, Manal A., Luque, Antoni
Publicado 2022

A stepwise docking molecular dynamics approach for simulating antibody recognition with substantial conformational changes

por Huang, Yang, Li, Zizhen, Hong, Qiyang, Zhou, Lizhi, Ma, Yue, Hu, Yisha, Xin, Jiabao, Li, Tingting, Kong, Zhibo, Zheng, Qingbing, Chen, Yixin, Zhao, Qinjian, Gu, Ying, Zhang, Jun, Wang, Yingbin, Yu, Hai, Li, Shaowei, Xia, Ningshao
Publicado 2022

Structural and biochemical characterization of the relaxosome auxiliary proteins encoded on the Bacillus subtilis plasmid pLS20

por Crespo, Isidro, Bernardo, Nerea, Cuppari, Anna, Calisto, Barbara M., Val-Calvo, Jorge, Miguel-Arribas, Andrés, Meijer, Wilfried J.J., Carpena, Xavi, Gil-Ortiz, Fernando, Malfois, Marc, Boer, D. Roeland
Publicado 2022

Evaluation of protein descriptors in computer-aided rational protein engineering tasks and its application in property prediction in SARS-CoV-2 spike glycoprotein

por Lim, Hocheol, Jeon, Hyeon-Nae, Lim, Seungcheol, Jang, Yuil, Kim, Taehee, Cho, Hyein, Pan, Jae-Gu, No, Kyoung Tai
Publicado 2022

Compounds targeting GPI biosynthesis or N-glycosylation are active against Plasmodium falciparum

por Fenollar, Àngel, Ros-Lucas, Albert, Pía Alberione, María, Martínez-Peinado, Nieves, Ramírez, Miriam, Ángel Rosales-Motos, Miguel, Y. Lee, Ling, Alonso-Padilla, Julio, Izquierdo, Luis
Publicado 2022

Identifying individualized risk subpathways reveals pan-cancer molecular classification based on multi-omics data

por Xu, Yanjun, Wang, Jingwen, Li, Feng, Zhang, Chunlong, Zheng, Xuan, Cao, Yang, Shang, Desi, Hu, Congxue, Xu, Yingqi, Mi, Wanqi, Li, Xia, Cao, Yan, Zhang, Yunpeng
Publicado 2022

SuPepMem: A database of innate immune system peptides and their cell membrane interactions

por Suarez-Leston, Fabián, Calvelo, Martin, Tolufashe, Gideon F., Muñoz, Alicia, Veleiro, Uxía, Porto, César, Bastos, Margarida, Piñeiro, Ángel, Garcia-Fandino, Rebeca
Publicado 2022

Identification of key miRNAs in prostate cancer progression based on miRNA-mRNA network construction

por Santo, Giulia Dal, Frasca, Marco, Bertoli, Gloria, Castiglioni, Isabella, Cava, Claudia
Publicado 2022

Regulatory patterns analysis of transcription factor binding site clustered regions and identification of key genes in endometrial cancer

por Tang, Xiaohan, Wang, Junting, Tao, Huan, Yuan, Lin, Du, Guifang, Ding, Yang, Xu, Kang, Bai, Xuemei, Li, Yaru, Sun, Yu, Huang, Xin, Zheng, Xiushuang, Li, Qianqian, Gong, Bowen, Zheng, Yang, Xu, Jingxuan, Xu, Xiang, Wang, Zhe, Bo, Xiaochen, Lu, Meisong, Li, Hao, Chen, Hebing
Publicado 2022

ADDAGMA: A database for domestic animal gut microbiome atlas

por Xu, Yueren, Lei, Bingbing, Zhang, Qingfeng, Lei, Yunjiao, Li, Cunyuan, Li, Xiaoyue, Yao, Rui, Hu, Ruirui, Liu, Kaiping, Wang, Yue, Cui, Yuying, Wang, Limin, Dai, Jihong, Li, Lei, Ni, Wei, Zhou, Ping, Liu, Ze-Xian, Hu, Shengwei
Publicado 2022

Conformational dynamics promotes disordered regions from function-dispensable to essential in evolved site-specific DNA recombinases

por Guillén-Pingarrón, Carla, Guillem-Gloria, Pedro M., Soni, Anjali, Ruiz-Gómez, Gloria, Augsburg, Martina, Buchholz, Frank, Anselmi, Massimiliano, Pisabarro, M. Teresa
Publicado 2022

A chromosome-level genome assembly of Amorphophallus konjac provides insights into konjac glucomannan biosynthesis

por Gao, Yong, Zhang, Yanan, Feng, Chen, Chu, Honglong, Feng, Chao, Wang, Haibo, Wu, Lifang, Yin, Si, Liu, Chao, Chen, Huanhuan, Li, Zhumei, Zou, Zhengrong, Tang, Lizhou
Publicado 2022

Considerations for constructing a protein sequence database for metaproteomics

por Blakeley-Ruiz, J. Alfredo, Kleiner, Manuel
Publicado 2022

Identification of (Z)-2-benzylidene-dihydroimidazothiazolone derivatives as tyrosinase inhibitors: Anti-melanogenic effects and in silico studies

por Choi, Heejeong, Young Ryu, Il, Choi, Inkyu, Ullah, Sultan, Jin Jung, Hee, Park, Yujin, Hwang, YeJi, Jeong, Yeongmu, Hong, Sojeong, Chun, Pusoon, Young Chung, Hae, Ryong Moon, Hyung
Publicado 2022

A review on marine plastisphere: biodiversity, formation, and role in degradation

por Du, Yuhui, Liu, Xinbei, Dong, Xusheng, Yin, Zhiqiu
Publicado 2022

How fullerene derivatives (FDs) act on therapeutically important targets associated with diabetic diseases

por Fjodorova, Natalja, Novič, Marjana, Venko, Katja, Drgan, Viktor, Rasulev, Bakhtiyor, Türker Saçan, Melek, Sağ Erdem, Safiye, Tugcu, Gulcin, Toropova, Alla P., Toropov, Andrey A.
Publicado 2022

Mechanistic insight into the impact of a bivalent ligand on the structure and dynamics of a GPCR oligomer

por Mansoor, Samman, Kayık, Gülru, Durdagi, Serdar, Sensoy, Ozge
Publicado 2022