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1por Wei, Ming-Ming, Zhou, Yong-Chun, Wen, Zhe-Sheng, Zhou, Bo, Huang, Yun-Chao, Wang, Gui-Zhen, Zhao, Xin-Chun, Pan, Hong-Li, Qu, Li-Wei, Zhang, Jian, Zhang, Chen, Cheng, Xin, Zhou, Guang-Biao“…CAR10 bound and stabilized transcription factor Y-box-binding protein 1 (YB-1), leading to up-regulation of the epidermal growth factor receptor (EGFR) and proliferation of lung cancer cells. …”
Publicado 2016
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2por Wang, Di, Chen, Xiaobo, Zhang, Zenglin, Liu, Danmei, Song, Gaoyuan, Kong, Xingchen, Geng, Shuaifeng, Yang, Jiayue, Wang, Bingnan, Wu, Liang, Li, Aili, Mao, LongEnlace del recurso
Publicado 2015
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3“…Moreover, we showed that overexpression MRTF-A had no remarkable effect to doxorubicin mediated apoptosis in cancer cells when knocking down Nrf2. Further studies showed that MRTF-A regulated the transcriptional activity of Nrf2 by forming a complex with SRF binding to the CarG box which existed on Nrf2 promoter region. …”
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4por Xiang, Yuan, Liao, Xing-Hua, Li, Jia-Peng, Li, Hui, Qin, Huan, Yao, Ao, Yu, Cheng-Xi, Hu, Peng, Guo, Wei, Gu, Chao-Jiang, Zhang, Tong-CunEnlace del recurso
Publicado 2017
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5por Ye, Gengtai, Huang, Kunzhai, Yu, Jiang, Zhao, Liying, Zhu, Xianjun, Yang, Qingbin, Li, Wende, Jiang, Yuming, Zhuang, Baoxiong, Liu, Hao, Shen, Zhiyong, Wang, Da, Yan, Li, Zhang, Lei, Zhou, Haipeng, Hu, Yanfeng, Deng, Haijun, Liu, Hao, Li, Guoxin, Qi, Xiaolong“…Mechanistically, we confirm miR-647 directly binds to the 3' untranslated regions of SRF mRNA, and SRF binds to the CArG box located at the MYH9 promoter. CCG-1423, an inhibitor of RhoA/SRF-mediated gene transcription, inhibits the expression of MYH9, especially in SRF downregulated cells. …”
Publicado 2017
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7por Friedrich, Mirco, Kowalewski, Karl-Friedrich, Proctor, Tanja, Garrow, Carly, Preukschas, Anas Amin, Kenngott, Hannes Götz, Fischer, Lars, Müller-Stich, Beat-Peter, Nickel, FelixEnlace del recurso
Publicado 2017
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8“…This study investigated whether radiation-induced overexpression of superoxide dismutase 2 (SOD2) exerts radio-sensitizing effects on tumor cells while having radio-protective effects on normal cells during radio-activated gene therapy for human colorectal cancer. A chimeric promoter, C(9)BC, was generated by directly linking nine tandem CArG boxes to a CMV basic promoter, after which lentiviral vectors containing GFP and SOD2 gene driven by the C(9)BC promoter were constructed. …”
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10por Gomaa, Sameh, West, Carly, Lopez, Ana Maria, Zhan, Tingting, Schnoll, Max, Abu-Khalaf, Maysa, Newberg, Andrew, Wen, Kuang-YiEnlace del recurso
Publicado 2022
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11por Kong, Hee Jeong, Kim, Julan, Kim, Ju-Won, Kim, Hyun-Chul, Noh, Jae Koo, Kim, Young-Ok, Kim, Woo-Jin, Yeo, Sang-Yeob, Park, Jung YounEnlace del recurso
Publicado 2019
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