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  1. 12681
  2. 12682
    “…Different glucose consumption dynamics were observed in presence of either casamino acids or the minimal set of amino acids, accompanied by major changes in butanoate formation. This was associated with a variation in both the toxin yield and a change in the ratio of toxin A to toxin B. …”
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  3. 12683
  4. 12684
    “…The quality target product profile and critical quality attributes of the proposed product were presented. Plackett–Burman screening design was employed to screen eight variables for their influences on the formulation’s critical characteristics. …”
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  5. 12685
    “…POS' levels accumulated in the fungal fermentation broth were optimized through a three step sequential statistical mathematical methodology; Plackett-Burman design (PBD), Box-Behnken design (BBD) and canonical analysis. …”
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  6. 12686
    “…Employing a hybrid statistical media optimization strategy of Plackett–Burman and Box-Behnken experimental designs in shake-flasks gave an increased phytase activity from an initial 66 IU/mL in 216 h to 160 IU/mL in a reduced time of 132 h. …”
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  7. 12687
    “…One-variable-at-a-time (OVAT) studies carried out to optimize the production of biosurfactant by B. subtilis ANR 88 resulted into maximum biosurfactant yield of 0.513 g/l in medium: molasses 4%, ammonium ferric citrate 0.25%, pH 7. Plackett–Burman design based statistical method for optimization increased the production of biosurfactant to 0.746 g/l, which is 3.6-fold of that produced on glucose. …”
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  8. 12688
    por Buchan, Daniel W A, Jones, David T
    Publicado 2017
    “…AVAILABILITY AND IMPLEMENTATION: All code used to generate these results and the computational protocol can be downloaded from https://github.com/DanBuchan/eigen_scripts. EigenTHREADER, the benchmark code and the data this paper is based on can be downloaded from: http://bioinfadmin.cs.ucl.ac.uk/downloads/eigenTHREADER/.…”
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  9. 12689
    “…Mixed fermentation of SC45/TD12 produced higher contents of higher alcohol (3-methyl-1-pentanol and phenylethyl alcohol), ethyl esters (ethyl decanoate and ethyl butanoate), terpenes and phenylacetaldehyde with less fatty acids (hexanoic acid, octanoic acid) and acetic acid, while BDX/TD12 generated more C(6) alcohol (1-hexanol) and acetate esters (ethyl acetate and isoamyl acetate). …”
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  10. 12690
    “…ALDH7A1 variants were not significantly associated with glaucoma in the NEIGHBORHOOD GWAS dataset, but this enzyme was identified as part of the butanoate pathway previously associated with glaucoma risk. …”
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  11. 12691
    “…The effects of different variables on Pb(2+) removal were estimated by a two-level Plackett–Burman factorial design to determine the most significant variables affecting Pb(2+) removal % from aqueous solutions. …”
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  12. 12692
    “…To resolve this issue, we determined DNA adducts induced by the three major TS carcinogens: benzo(a)pyrene (BP), 4-(methylnitrosamine)-1-(3-pyridyl)-1-butanoe (NNK), and aldehydes in humans and mice. In mice, TS induces abundant aldehyde-induced γ-hydroxy-propano-deoxyguanosine (γ-OH-PdG) and α-methyl-γ-OH-PdG adducts in the lung and bladder, but not in the heart and liver. …”
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  13. 12693
    “…The comprehensive population comparisons reveal that Han Chinese is a homogenous population and has the genetically closer relationship with Hmong-Mien-speaking groups than Tibetan-Burman-speaking and Turkic-speaking populations. In summary, AGCU X19 PCR amplification system is highly polymorphic and informative in Guizhou Han and Han Chinese populations. …”
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  14. 12694
    “…To achieve maximum metabolite production, the growth of Streptomyces 1–14 was optimized through response surface methodology employing Plackett-Burman design, path of steepest ascent determinations and Box-Behnken design. …”
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  15. 12695
    “…METHODS AND ANALYSIS: Four hundred first trimester pregnant women from either Myanmar or Thailand of either Karen or Burman ethnicity, with a viable, singleton pregnancy will be enrolled in this non-interventional, prospective pregnancy birth cohort study and will be followed through to the postpartum period. …”
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  16. 12696
    “…Among flavor volatiles, ethyl butanoate, valencene, decanal and other ethyl esters are lower, but many monoterpenes are higher in symptomatic fruit compared to healthy and asymptomatic fruit. …”
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  17. 12697
    “…We modeled toxicity in the FMIGRT group using the Lyman Kutcher Burman (LKB) and Univariate Logistic Regression (ULR) models, and we modeled toxicity in USGRT group using the ULR model. …”
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  18. 12698
    “…After optimization of the Plackett–Burman (PB) design and response surface methodology (RSM), the yield of oligosaccharides was increased by 36.1% from 2.71 to 3.09 g L(−1) in a 250-mL fermenter with optimized parameters: 30 g L(−1) G. lemaneiformis powder, 4.84 g L(−1) (NH4)(2)SO(4), 44.8-mL working medium volume at 36.7°C, and a shaking speed of 200 × g for 42 h. …”
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  19. 12699
    “…In addition, comparative transcriptome analysis of low and high yield mutants, and a parental strain revealed the mechanistic insight of biosynthesis pathways, in which metabolic pathways including butanoate metabolism, starch and sucrose metabolism and glyoxylate metabolism were closely associated with salinomycin biosynthesis. …”
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  20. 12700
    “…The statistical design of Plackett–Burman and face centered central composite design were employed to optimize L-asparaginase production by Streptomyces brollosae NEAE-115. …”
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