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41“…METHODS: To test this idea the supramaximal caerulein model was used to induce acute pancreatitis in wild type and CF mice. …”
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43por Heindl, Mario, Tuennemann, Jan, Sommerer, Ines, Mössner, Joachim, Hoffmeister, Albrecht“…METHODS: Acute experimental pancreatitis was induced by intraperitoneal injection of caerulein in homozygote Bace1 (-/-) mice and wild type mice. …”
Publicado 2015
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44por Waldeck-Weiermair, Markus, Bischof, Helmut, Blass, Sandra, Deak, Andras T., Klec, Christiane, Graier, Thomas, Roller, Clara, Rost, Rene, Eroglu, Emrah, Gottschalk, Benjamin, Hofmann, Nicole A., Graier, Wolfgang F., Malli, Roland“…Cameleons are sophisticated genetically encoded fluorescent probes that allow quantifying cellular Ca(2+) signals. …”
Publicado 2015
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45por Pandey, Kishor, Ferreira, Pedro E., Ishikawa, Takeshi, Nagai, Takeharu, Kaneko, Osamu, Yahata, Kazuhide“…Here we analyze Ca(2+) homeostasis via a new approach using transgenic P. falciparum expressing the Ca(2+) sensor yellow cameleon (YC)-Nano. We found that cytosolic Ca(2+) concentration is maintained at low levels only during the intraerythrocytic trophozoite stage (30 nM), and is increased in the other blood stages (>300 nM). …”
Publicado 2016
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46por Hofmann, Albrecht W.Enlace del recurso
Publicado 2021
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48Pro-inflammatory effects of hydrogen sulphide on substance P in caerulein-induced acute pancreatitispor Bhatia, Madhav, Sidhapuriwala, Jenab N, Wei Ng, Siaw, Tamizhselvi, Ramasamy, Moochhala, Shabbir M“…The present study was aimed to investigate the interplay between pro-inflammatory effects of H(2)S and SP in a murine model of caerulein-induced acute pancreatitis. Acute pancreatitis was induced in mice by 10 hourly intraperitoneal injections of caerulein (50 (g/kg). …”
Publicado 2008
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49“…The current study aimed to isolate key transcription factors (TFs) in caerulein-induced pancreatitis, and to identify the difference between wild type and Mist1 knockout (KO) mice, in order to elucidate the contribution of Mist1 to pancreatitis. …”
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50por Bonior, Joanna, Ceranowicz, Piotr, Gajdosz, Ryszard, Kuśnierz-Cabala, Beata, Pierzchalski, Piotr, Warzecha, Zygmunt, Dembiński, Artur, Pędziwiatr, Michał, Kot, Michalina, Leja-Szpak, Anna, Nawrot-Porąbka, Katarzyna, Link-Lenczowski, Paweł, Olszanecki, Rafał, Bartuś, Krzysztof, Jaworek, Jolanta“…After isolation, pancreatic acinar cells were incubated in caerulein-free or caerulein containing solution. AR42J cells were incubated under basal conditions and stimulated with caerulein, GHRL or a combination of the above. …”
Publicado 2017
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51Puerarin Ameliorates Caerulein-Induced Chronic Pancreatitis via Inhibition of MAPK Signaling Pathwaypor Zeng, Xiang-Peng, Zeng, Jing-Hui, Lin, Xia, Ni, Yan-Hong, Jiang, Chuan-Shen, Li, Da-Zhou, He, Xiao-Jian, Wang, Rong, Wang, Wen“…H&E staining, Sirius Red staining, qRT-PCR and Western blotting analysis of fibrosis and inflammation related genes of pancreatic tissues showed that puerarin notably ameliorated pancreatic atrophy, inflammation and fibrosis in a model of caerulein-induced murine CP. Western blotting analysis of pancreatic tissues showed the phosphorylation level of MAPK family proteins (JNK1/2, ERK1/2 and p38 MAPK) significantly increased after modeling of cerulein, while puerarin could inhibit their phosphorylation levels to a certain extent. …”
Publicado 2021
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55por Greotti, Elisa, Fortunati, Ilaria, Pendin, Diana, Ferrante, Camilla, Galla, Luisa, Zentilin, Lorena, Giacca, Mauro, Kaludercic, Nina, Di Sante, Moises, Mariotti, Letizia, Lia, Annamaria, Gómez-Gonzalo, Marta, Sessolo, Michele, Carmignoto, Giorgio, Bozio, Renato, Pozzan, Tullio“…We have modified the cytosolic and mitochondria-targeted Cameleon GECIs by (1) substituting the donor ECFP with mCerulean3, a brighter and more stable fluorescent protein with a single exponential lifetime; (2) extensively modifying the constructs to improve targeting efficiency and fluorescence changes caused by Ca(2+) binding; and (3) inserting the cDNAs into adeno-associated viral vectors for in vivo expression. …”
Publicado 2019
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56por Greotti, Elisa, Fortunati, Ilaria, Pendin, Diana, Ferrante, Camilla, Galla, Luisa, Zentilin, Lorena, Giacca, Mauro, Kaludercic, Nina, Di Sante, Moises, Mariotti, Letizia, Lia, Annamaria, Gómez-Gonzalo, Marta, Sessolo, Michele, Di Lisa, Fabio, Carmignoto, Giorgio, Bozio, Renato, Pozzan, TullioEnlace del recurso
Publicado 2019
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57por Wang, Li‐Juan, He, Lin, Hao, Lu, Guo, Hong‐Lei, Zeng, Xiang‐Peng, Bi, Ya‐Wei, Lu, Guo‐Tao, Li, Zhao‐Shen, Hu, Liang‐Hao“…Here, we investigated the effect of isoliquiritigenin (ILG), a chalcone‐type dietary compound derived from licorice, on pancreatic fibrosis and inflammation in a model of caerulein‐induced murine CP, and the results indicated that ILG notably alleviated pancreatic fibrosis and infiltration of macrophages. …”
Publicado 2020
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58por Hagen, Cristina M, Roth, Eva, Graf, Theresia Reding, Verrey, François, Graf, Rolf, Gupta, Anurag, Pellegrini, Giovanni, Poncet, Nadège, Camargo, Simone Mafalda Rodrigues“…METHODS: AP was induced with caerulein (cae) injections in female and male mice expressing LAT1 or after its knockout (LAT1 Cre/LoxP). …”
Publicado 2022
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59por Wögenstein, Karl L., Szabo, Sandra, Lunova, Mariia, Wiche, Gerhard, Haybaeck, Johannes, Strnad, Pavel, Boor, Peter, Wagner, Martin, Fuchs, Peter“…We analyzed epiplakin’s expression in healthy and inflamed pancreatic tissue and compared wild-type and EPPK(−/−) mice during caerulein-induced acute pancreatitis. We found that epiplakin was expressed primarily in ductal cells of the pancreas and colocalized with apicolateral keratin bundles in murine pancreatic acinar cells. …”
Publicado 2014
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60por Oshima, Yusuke, Imamura, Takeshi, Shintani, Atsuko, Kajiura-Kobayashi, Hiroko, Hibi, Terumasa, Nagai, Takeharu, Nonaka, Shigenori, Nemoto, Tomomi“…Yellow Cameleons are genetically encoded Ca(2+) indicators in which cyan and yellow fluorescent proteins and calmodulin work together as a fluorescence (Förster) resonance energy transfer Ca(2+)-sensor probe. …”
Publicado 2014
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