Autism-associated SHANK3 missense point mutations impact conformational fluctuations and protein turnover at synapses

por Bucher, Michael, Niebling, Stephan, Han, Yuhao, Molodenskiy, Dmitry, Hassani Nia, Fatemeh, Kreienkamp, Hans-Jürgen, Svergun, Dmitri, Kim, Eunjoon, Kostyukova, Alla S, Kreutz, Michael R, Mikhaylova, Marina
Publicado 2021

Reappraising the role of the vagus nerve in GLP‐1‐mediated regulation of eating

por Brierley, Daniel I., de Lartigue, Guillaume
Publicado 2021

Fibroblast mechanotransduction network predicts targets for mechano-adaptive infarct therapies

por Rogers, Jesse D, Richardson, William J
Publicado 2022

Targeting β-catenin in acute myeloid leukaemia: past, present, and future perspectives

por Wagstaff, Megan, Coke, Brandon, Hodgkiss, Georgia R., Morgan, Rhys G.
Publicado 2022

Multi‐faceted role of pyroptosis mediated by inflammasome in liver fibrosis

por Yang, Hui, Wang, Juan, Liu, Zhen‐Guo
Publicado 2022

Non-small-cell lung cancer: how to manage MET exon 14 skipping mutant disease

por Blaquier, Juan Bautista, Recondo, Gonzalo
Publicado 2022

Processing DNA lesions during mitosis to prevent genomic instability

por Audrey, Anastasia, de Haan, Lauren, van Vugt, Marcel A.T.M., de Boer, H. Rudolf
Publicado 2022

Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors

por Cohen, Hadar, Baram, Noam, Fridman, Chaya Mushka, Edry-Botzer, Liat, Salomon, Dor, Gerlic, Motti
Publicado 2022

Targeting G-quadruplexes to achieve antiviral activity

por Ruggiero, Emanuela, Richter, Sara N.
Publicado 2023

Lumenal components of cytoplasmic microtubules

por Tsuji, Chisato, Dodding, Mark P.
Publicado 2022

Inflammation induces endothelial‐to‐mesenchymal transition and promotes vascular calcification through downregulation of BMPR2

por Sánchez‐Duffhues, Gonzalo, García de Vinuesa, Amaya, van de Pol, Vera, Geerts, Marlieke E, de Vries, Margreet R, Janson, Stef GT, van Dam, Hans, Lindeman, Jan H., Goumans, Marie‐José, ten Dijke, Peter
Publicado 2019

Cripto favors chondrocyte hypertrophy via TGF‐β SMAD1/5 signaling during development of osteoarthritis

por Garcia de Vinuesa, Amaya, Sanchez‐Duffhues, Gonzalo, Blaney‐Davidson, Esmeralda, van Caam, Arjan, Lodder, Kirsten, Ramos, Yolande, Kloppenburg, Margreet, Meulenbelt, Ingrid, van der Kraan, Peter, Goumans, Marie‐José, ten Dijke, Peter
Publicado 2021

Genomic profiling identifies genes and pathways dysregulated by HEY1–NCOA2 fusion and shines a light on mesenchymal chondrosarcoma tumorigenesis

por Qi, Wenqing, Rosikiewicz, Wojciech, Yin, Zhaohong, Xu, Beisi, Jiang, Huihong, Wan, Shibiao, Fan, Yiping, Wu, Gang, Wang, Lu
Publicado 2022

Overexpression screen of chromosome 21 genes reveals modulators of Sonic hedgehog signaling relevant to Down syndrome

por Moyer, Anna J., Fernandez, Fabian-Xosé, Li, Yicong, Klinedinst, Donna K., Florea, Liliana D., Kazuki, Yasuhiro, Oshimura, Mitsuo, Reeves, Roger H.
Publicado 2023

The E2 ubiquitin-conjugating enzymes UBE2D1 and UBE2D2 regulate VEGFR2 dynamics and endothelial function

por Critchley, William R., Smith, Gina A., Zachary, Ian C., Harrison, Michael A., Ponnambalam, Sreenivasan
Publicado 2023

The translation initiation factor homolog eif4e1c regulates cardiomyocyte metabolism and proliferation during heart regeneration

por Rao, Anupama, Lyu, Baken, Jahan, Ishrat, Lubertozzi, Anna, Zhou, Gao, Tedeschi, Frank, Jankowsky, Eckhard, Kang, Junsu, Carstens, Bryan, Poss, Kenneth D., Baskin, Kedryn, Goldman, Joseph Aaron
Publicado 2023

Altered binding affinity of SIX1-Q177R correlates with enhanced WNT5A and WNT pathway effector expression in Wilms tumor

por Stevenson, Matthew J., Phanor, Sabrina K., Patel, Urvi, Gisselbrecht, Stephen S., Bulyk, Martha L., O'Brien, Lori L.
Publicado 2023

Multiple Hsp70 Isoforms in the Eukaryotic Cytosol: Mere Redundancy or Functional Specificity?

por Kabani, Mehdi, Martineau, Céline N
Publicado 2008

The roles of p27(Kip1) and DNA damage signalling in the chemotherapy-induced delayed cell cycle checkpoint

por Liontos, Michalis, Velimezi, Georgia, Pateras, Ioannis S, Angelopoulou, Roxani, Papavassiliou, Athanasios G, Bartek, Jiri, Gorgoulis, Vassilis G
Publicado 2010

Activation of Wnt signalling in stroma from pancreatic cancer identified by gene expression profiling

por Pilarsky, Christian, Ammerpohl, Ole, Sipos, Bence, Dahl, Edgar, Hartmann, Arndt, Wellmann, Axel, Braunschweig, Till, Löhr, Matthias, Jesnowski, Ralf, Friess, Helmut, Wente, Moritz Nicolas, Kristiansen, Glen, Jahnke, Beatrix, Denz, Axel, Rückert, Felix, Schackert, Hans K, Klöppel, Günter, Kalthoff, Holger, Saeger, Hans Detlev, Grützmann, Robert
Publicado 2008