An intronic ncRNA-dependent regulation of SORL1 expression affecting Aβ formation is upregulated in post-mortem Alzheimer's disease brain samples

por Ciarlo, Eleonora, Massone, Sara, Penna, Ilaria, Nizzari, Mario, Gigoni, Arianna, Dieci, Giorgio, Russo, Claudio, Florio, Tullio, Cancedda, Ranieri, Pagano, Aldo
Publicado 2013

Inhibition of redox/Fyn/c-Cbl pathway function by Cdc42 controls tumour initiation capacity and tamoxifen sensitivity in basal-like breast cancer cells

por Chen, Hsing-Yu, Yang, Yin M, Stevens, Brett M, Noble, Mark
Publicado 2013

Selection of genes for gene-environment interaction studies: a candidate pathway-based strategy using asthma as an example

por Rava, Marta, Ahmed, Ismaïl, Demenais, Florence, Sanchez, Margaux, Tubert-Bitter, Pascale, Nadif, Rachel
Publicado 2013

Diversity and plasticity in Rab GTPase nucleotide release mechanism has consequences for Rab activation and inactivation

por Langemeyer, Lars, Nunes Bastos, Ricardo, Cai, Yiying, Itzen, Aymelt, Reinisch, Karin M, Barr, Francis A
Publicado 2014

Muscovy duck reovirus p10.8 protein localizes to the nucleus via a nonconventional nuclear localization signal

por Guo, Dongchun, Qiu, Na, Shaozhou, Wulin, Bai, Xiaofei, He, Yilong, Zhang, Qingshan, Zhao, Jian, Liu, Ming, Zhang, Yun
Publicado 2014

Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1

por Jia, Xiaofei, Weber, Erin, Tokarev, Andrey, Lewinski, Mary, Rizk, Maryan, Suarez, Marissa, Guatelli, John, Xiong, Yong
Publicado 2014

An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases

por Boucher, Jeffrey I, Jacobowitz, Joseph R, Beckett, Brian C, Classen, Scott, Theobald, Douglas L
Publicado 2014

AIP augments CARMA1-BCL10-MALT1 complex formation to facilitate NF-κB signaling upon T cell activation

por Schimmack, Gisela, Eitelhuber, Andrea C, Vincendeau, Michelle, Demski, Katrin, Shinohara, Hisaaki, Kurosaki, Tomohiro, Krappmann, Daniel
Publicado 2014

Inhibitors of endocytosis prevent Wnt/Wingless signalling by reducing the level of basal β-catenin/Armadillo

por Gagliardi, Maria, Hernandez, Ana, McGough, Ian J., Vincent, Jean-Paul
Publicado 2014

Screen for mitochondrial DNA copy number maintenance genes reveals essential role for ATP synthase

por Fukuoh, Atsushi, Cannino, Giuseppe, Gerards, Mike, Buckley, Suzanne, Kazancioglu, Selena, Scialo, Filippo, Lihavainen, Eero, Ribeiro, Andre, Dufour, Eric, Jacobs, Howard T
Publicado 2014

RNA-Seq and Network Analysis Revealed Interacting Pathways in TGF-β-Treated Lung Cancer Cell Lines

por Li, Yan, Rouhi, Omid, Chen, Hankui, Ramirez, Rolando, Borgia, Jeffrey A, Deng, Youping
Publicado 2015

Model-Based Design of a Decision Tree for Treating HER2+ Cancers Based on Genetic and Protein Biomarkers

por Kirouac, DC, Lahdenranta, J, Du, J, Yarar, D, Onsum, MD, Nielsen, UB, McDonagh, CF
Publicado 2015

Mapping and analysis of Caenorhabditis elegans transcription factor sequence specificities

por Narasimhan, Kamesh, Lambert, Samuel A, Yang, Ally WH, Riddell, Jeremy, Mnaimneh, Sanie, Zheng, Hong, Albu, Mihai, Najafabadi, Hamed S, Reece-Hoyes, John S, Fuxman Bass, Juan I, Walhout, Albertha JM, Weirauch, Matthew T, Hughes, Timothy R
Publicado 2015

Divergent androgen regulation of unfolded protein response pathways drives prostate cancer

por Sheng, Xia, Arnoldussen, Yke Jildouw, Storm, Margrethe, Tesikova, Martina, Nenseth, Hatice Zeynep, Zhao, Sen, Fazli, Ladan, Rennie, Paul, Risberg, Bjørn, Wæhre, Håkon, Danielsen, Håvard, Mills, Ian G, Jin, Yang, Hotamisligil, Gökhan, Saatcioglu, Fahri
Publicado 2015

The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies

por Cottee, Matthew A, Muschalik, Nadine, Johnson, Steven, Leveson, Joanna, Raff, Jordan W, Lea, Susan M
Publicado 2015

Predominant contribution of cis-regulatory divergence in the evolution of mouse alternative splicing

por Gao, Qingsong, Sun, Wei, Ballegeer, Marlies, Libert, Claude, Chen, Wei
Publicado 2015

Nitric Oxide-Mediated Posttranslational Modifications: Impacts at the Synapse

por Bradley, Sophie A., Steinert, Joern R.
Publicado 2016

N-docosahexaenoylethanolamine regulates Hedgehog signaling and promotes growth of cortical axons

por Kharebava, Giorgi, Rashid, Mohammad A., Lee, Ji-Won, Sarkar, Sarmila, Kevala, Karl, Kim, Hee-Yong
Publicado 2015

Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma

por Grosso, Ana R, Leite, Ana P, Carvalho, Sílvia, Matos, Mafalda R, Martins, Filipa B, Vítor, Alexandra C, Desterro, Joana MP, Carmo-Fonseca, Maria, de Almeida, Sérgio F
Publicado 2015

A K(+)-selective CNG channel orchestrates Ca(2+) signalling in zebrafish sperm

por Fechner, Sylvia, Alvarez, Luis, Bönigk, Wolfgang, Müller, Astrid, Berger, Thomas K, Pascal, Rene, Trötschel, Christian, Poetsch, Ansgar, Stölting, Gabriel, Siegfried, Kellee R, Kremmer, Elisabeth, Seifert, Reinhard, Kaupp, U Benjamin
Publicado 2015