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501por Ma, Lin, Yu, Ai-Hua, Sun, Li-Li, Gao, Wan, Zhang, Meng-Meng, Su, Ya-Lun, Liu, Hua, Ji, Tengfei“…Two new bidesmoside triterpenoid saponins which were identifed as 28-O-β-d-xylopyranosyl(1→3)-β-d-xylopyranosyl(1→4)-α-l-rhamnopyranosyl(1→2)-[α-l-rhamno-pyranosyl(1→3)]-β-d-fucopyranosyl gypsogenin 3-O-β-d-glucopyranosyl (1→2)-β-d-glucopyranosiduronic acid (C1) and 28-O-β-d-xylopyranosyl(1→4)-α-l-rhamnopyranosyl (1→2)-[α-l-rhamnopyranosyl(1→3)]-β-d-fucopyranosyl gypsogenin 3-O-β-d-gluco-pyranosyl(1→2)-β-d-glucopyranosiduronic acid (C2) were isolated together with two known compounds from the seeds of Momordica charantia L. Their structures were elucidated by the combination of mass spectrometry (MS), one and two-dimensional NMR experiments and chemical reactions.…”
Publicado 2014
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502por Söder, Josefin, Höglund, Katja, Dicksved, Johan, Hagman, Ragnvi, Eriksson Röhnisch, Hanna, Moazzami, Ali Ata, Wernersson, Sara“…Notably, mean fasting carnitine concentration in overweight dogs (9.4 ± 4.2 µM) was close to a proposed reference limit for carnitine insufficiency. …”
Publicado 2019
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503por Chen, Si, Hu, Yingying, Huang, Yumei, Nan, Yan, Zhou, Xiaojian, Chen, Shangqin, Lin, Jin, Lin, Zhenlang“…BACKGROUND: Maternofetal carnitine transport through the placenta is the main route of fetal carnitine uptake. …”
Publicado 2019
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504“…SIMPLE SUMMARY: Endogenous carnitine synthesis is reduced by heat stress, and we hypothesized that carnitine supplementation would improve lipid metabolism and performance of dairy goats when exposed to high ambient temperature. …”
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505“…We reiterate the role of L-carnitine and vitamin B complex for the treatment of asparaginase-induced hepatotoxicity.…”
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507por JIANG, Wen-Jie, YAO, Xue-Rui, ZHAO, Yu-Han, GAO, Qing-Shan, JIN, Qing-Guo, LI, Ying-Hua, YAN, ang-Guo, XU, Yong-Nan“…L-carnitine (LC) is well known for its antioxidant activity. …”
Publicado 2019
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508“…Carnitine is an amino acid derivative, which plays several important roles in human physiology, in the central nervous system, and for mitochondrial metabolism, in particular. …”
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509por Okubo, Hironao, Ando, Hitoshi, Ishizuka, Kei, Kitagawa, Ryuta, Okubo, Shoki, Saito, Hiroaki, Kokubu, Shigehiro, Miyazaki, Akihisa, Ikejima, Kenichi, Shiina, Shuichiro, Nagahara, Akihito“…One mechanism contributing to development of fatigue might involve abnormal adenosine triphosphate synthesis that is caused by carnitine deficiency. To address this possibility, we examined the relationship between carnitine levels and fatigue during lenvatinib treatment. …”
Publicado 2020
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510“…Carnitine palmitoyltransferase (CPT) catalyzes the transfer of long- and medium-chain fatty acids from cytoplasm into mitochondria, where oxidation of fatty acids takes place. …”
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511por Lee, Ganghee, Nguyen, Thi Thanh Hanh, Lim, Tae Yun, Lim, Juho, Park, Byeongsu, Lee, Seonmin, Mok, Il-Kyoon, Pal, Kunal, Lim, Sangyong, Kim, Doman“…Fourteen ginsenosides and l-carnitine were analyzed in the fermented wild ginseng by the ultra high pressure liquid chromatography–mass spectrometry (UPLC–MS) system. …”
Publicado 2020
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512por Pennisi, Manuela, Lanza, Giuseppe, Cantone, Mariagiovanna, D’Amico, Emanuele, Fisicaro, Francesco, Puglisi, Valentina, Vinciguerra, Luisa, Bella, Rita, Vicari, Enzo, Malaguarnera, Giulia“…Several studies explored the effects of acetyl-L-carnitine (ALC) in dementia, suggesting a role in slowing down cognitive decline. …”
Publicado 2020
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513por Sun, Man, Zhao, Baihui, He, Sainan, Weng, Ruopeng, Wang, Binqiao, Ding, Yunping, Huang, Xinwen, Luo, Qiong“…The present study is aimed at evaluating carnitine alteration in fatty acid metabolism in the second trimester of pregnancy and the correlation between carnitine and GDM. …”
Publicado 2020
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514“…Bitter melon or bitter gourd (Momordica charantia) is a nutrient-rich medicinal plant cultivated in tropical and subtropical regions of many countries. …”
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515por Orr, Asuka A., He, Shujun, Wang, Meichen, Goodall, Alicia, Hearon, Sara E., Phillips, Timothy D., Tamamis, Phanourios“…Molecular dynamics simulations predicted that parent, unamended, clay has higher binding propensity for BPA and BPS than for DBP and DEHP; carnitine-amended clay improved BPA and BPS binding, through carnitine simultaneously anchoring to the clay through its quaternary ammonium cation and forming hydrogen bonds with BPA and BPS. …”
Publicado 2020
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516por Sato, Shinya, Namisaki, Tadashi, Furukawa, Masanori, Saikawa, Soichiro, Kawaratani, Hideto, Kaji, Kosuke, Takaya, Hiroaki, Shimozato, Naotaka, Sawada, Yasuhiko, Kitagawa, Koh, Moriya, Kei, Akahane, Takemi, Mitoro, Akira, Hoki, Noriyuki, Ann, Tatsuichi, Yoshiji, Hitoshi“…L-carnitine (4-N-trimethylammonium-3-hydroxybutyric acid) is the physiologically active form of carnitine and is a natural compound that has been shown to exhibit antioxidant activity. …”
Publicado 2020
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517por Yang, Kang, Wang, Na, Guo, Hai-Tao, Wang, Jing-Ran, Sun, Huan-Huan, Sun, Liang-Zhen, Yue, Shun-Li, Zhou, Jia-Bo“…OBJECTIVE: This study was conducted to investigate the effect of L-carnitine on the pig semen characteristics during storage. …”
Publicado 2020
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518“…Non-targeted metabolomics and amino acid- or carnitine-targeted metabolomics were conducted, then, plasma samples of mice induced by imiquimod (IMQ) were subjected to the amino acid- and carnitine-targeted metabolomic profiling. …”
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519“…An example is the use of the widely advertised bitter melon (Momordica charantia) in treating diabetes despite its unproven efficacy. …”
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520“…Carnitine is required for transporting fatty acids into the mitochondria for β-oxidation. …”
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