Materias dentro de su búsqueda.
Materias dentro de su búsqueda.
Derechos civiles
53
Garantías constitucionales
51
Derechos humanos
42
Derecho constitucional
33
Leyes y legislación
30
Amparo
28
Historia
26
Garantías (Derecho)
23
Procedimiento penal
17
Control de calidad
10
Derecho civil
10
Filosofía antigua
10
Filosofía
9
Garantía de calidad
9
Procedimiento civil
7
Condiciones sociales
6
Análisis
5
Crítica e interpretación
5
Derecho
5
Derecho procesal
5
Tribunales constitucionales
5
Administración de justicia
4
Alimentos
4
Constitución
4
Derecho fiscal
4
Derecho penal
4
Educación
4
Filosofía griega
4
Garantías individuales
4
Indígenas de México
4
-
5281“…For lipid metabolism, the expression of sterol regulatory element-binding protein 1, long-chain acyl-CoA synthetase 1, and fatty acid synthase in the liver was decreased in HC group, whereas carnitine palmitoyltransferase 1α and peroxisome proliferator activated receptor α were increased. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5282por Han, Buying, Meng, Yuqiong, Tian, Haining, Li, Changzhong, Li, Yaopeng, Gongbao, Caidan, Fan, Wenyan, Ma, Rui“…The results showed that 1) regarding stress response, hypoxia increased plasma levels of cortisol, heat shock protein 70 (HSP-70), lysozyme, alanine aminotransferase (ALT), aspartate aminotransferase (AST) and creatine phosphokinase (CPK); induced the expression of hepatic genes encoding nuclear factor erythroid 2 related factor 2 (Nrf2), interferon γ (IFN-γ) and interleukin-1β (IL-1β). 2) Regarding metabolism response, hypoxia increased plasma levels of globulin (GLOB), glucose (GLU), triglyceride (TG) and lactate dehydrogenase (LDH); upregulated the hepatic gene expression of phosphoenolpyruvate carboxykinase, (PEPCK), pyruvate dehydrogenase kinase (PDK1), acetyl-CoA carboxylase (ACC) and acetyl-CoA oxidase (ACO); downregulated the hepatic gene expression of carnitine palmitoyl transferase 1 (CPT1); and unchanged the expression of hepatic genes in glycolysis and autophagy. 3) In response to hypoxia-inducible factors (HIFs), the hepatic HIF-2α gene was activated in the hypoxia group, but HIF-1α gene expression remained unchanged. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5283por Guo, Qiuping, Zhang, Lingyu, Yin, Yunju, Gong, Saiming, Yang, Yuhuan, Chen, Sisi, Han, Mengmeng, Duan, Yehui“…Supplementation with TAU2 and TAU3 increased the relative mRNA expression levels of peroxisome proliferator-activated receptor α, adipose triglyceride lipase, lipoprotein lipase, hormone-sensitive lipase and carnitine palmitoyl transferase 1 in liver compared with the OFO group (p < 0.05). …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5284por Manjunath, Meghana, Swaroop, Sai, Pradhan, Sai Sanwid, Rao K, Raksha, Mahadeva, Raghunandan, Sivaramakrishnan, Venketesh, Choudhary, Bibha“…Global metabolomic profiling using LC-MS revealed that Oncometabolites like carnitine, oleic acid, glycine, and arginine were elevated in tumour mice compared to normal and were downregulated upon Disarib treatment. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5285por Lin, Tong, Yang, Wan-qi, Luo, Wen-wei, Zhang, Li-li, Mai, Yan-qi, Li, Zi-qing, Liu, Si-tong, Jiang, Lu-jing, Liu, Pei-qing, Li, Zhuo-ming“…In the replicative senescence model and H(2)O(2)-induced premature senescence model of primary cultured human umbilical vein endothelial cells (HUVECs), fatty acid oxidation (FAO) was suppressed and fatty acid profile was disturbed, accompanied by downregulation of proteins associated with fatty acid uptake and mitochondrial entry, in particular the FAO rate-limiting enzyme carnitine palmitoyl transferase 1A (CPT1A). Impairment of fatty acid metabolism by silencing CPT1A or CPT1A inhibitor etomoxir facilitated the development of endothelial senescence, as implied by the increase of p53, p21, and senescence-associated β-galactosidase, as well as the decrease of EdU-positive proliferating cells. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5286por Ye, Chengyin, Wu, Jinghua, Reiss, Jonathan D., Sinclair, Tiffany J., Stevenson, David K., Shaw, Gary M., Chace, Donald H., Clark, Reese H., Prince, Lawrence S., Ling, Xuefeng Bruce, Sylvester, Karl G.“…Citrulline, alanine, glutamate, tyrosine, propionylcarnitine, free carnitine, acetylcarnitine, hydroxybutyrylcarnitine, and most median-chain ACs (C(5):C(10)) were the most associated metabolites down-regulated in BPD babies over the early days of life, whereas phenylalanine, methionine, and hydroxypalmitoylcarnitine were observed to be up-regulated in BPD babies. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5287por Bangarbale, Surabhi, Shepard, Blythe D., Bansal, Shivani, Jayatilake, Meth M., Kurtz, Ryan, Levi, Moshe, Ecelbarger, Carolyn M.“…In contrast, although overall lipid quantity was not higher, several lipid species were increased by EMPA, including those of the classes, phosphatidic acids, phosphatidylcholines, and carnitines. Overall, these analyses suggest a protection from extensive metabolic load and the corresponding oxidative stress with EMPA in kidney. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5288por Li, Dehong, Lu, Yan, Zhao, Fenghui, Yan, Li, Yang, Xingwen, Wei, Lianhua, Yang, Xiaoyan, Yuan, Xiumei, Yang, Kehu“…RESULTS: The metabolomic analysis found adipylcarnitine (C6DC), 3-hydroxy-hexadecanoylcarnitine (C16OH), hexanoylcarnitine (C6), free carnitine (C0) and arginine (ARG) were differentially expressed (all VIP >1) and could distinguish GC patients from AG and SG cases. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5289por Gadoa, Zahraa Alaaeldein, Moustafa, Ahmed Hussein, El Rayes, Samir Mohamed, Arisha, Ahmed A., Mansour, Mohamed Fouad“…The results indicated that serum glucose, total cholesterol (TC), triacylglycerol (TG), low-density lipoprotein-cholesterol (LDL-c), very low-density lipoprotein-cholesterol (VLDL-c), malondialdehyde, alanine aminotransferase (ALT), aspartate aminotransferase (AST), and peroxisome proliferator-activated receptor gamma coactivator 1-alpha PGC-1α mRNA expressions were increased in the diabetic group versus the control group, while serum insulin, high-density lipoprotein-cholesterol (HDL-c), superoxide dismutase (SOD), and carnitine palmitoyltransferase 1A (CPT1A) mRNA expression levels were decreased. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5290por Chong, Cher-Rin, Liu, Saifei, Imam, Hasan, Heresztyn, Tamila, Sallustio, Benedetta C., Chirkov, Yuliy Y., Horowitz, John D.“…Perhexiline (Px) inhibits carnitine palmitoyltransferase 1 (CPT1), which controls uptake of long chain fatty acids into mitochondria. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5291por Han, Yunsheng, Tang, Chaohua, Zhao, Qingyu, Fan, Shijie, Yang, Peilong, Zhang, Junmin“…Diets also altered enterocyte metabolism in the jejunum by upregulating peroxisome-proliferator-activated receptor α expression but downregulating carnitine palmitoyltransferase 1 level when compared with CON or LPS groups. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5292por Hwang, Sueyoun, Hood, Robert B., Hauser, Russ, Schwartz, Joel, Laden, Francine, Jones, Dean, Liang, Donghai, Gaskins, Audrey J.“…Key pathways of overlap included vitamin D3 metabolism (both columns), bile acid biosynthesis (both columns), C21-steroid hormone metabolism (HILIC), androgen and estrogen metabolism (HILIC), vitamin A metabolism (HILIC), carnitine shuttle (HILIC), and prostaglandin formation (C18). …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5293por Kaviany, Saara, Bartkowiak, Todd, Dulek, Daniel E., Khan, Yasmin W., Hayes, Madeline J., Schaefer, Samuel G., Ye, Xiang, Dahunsi, Debolanle O., Connelly, James A., Irish, Jonathan M., Rathmell, Jeffrey C.“…Immune cell metabolism directly influences cell function, and the STAT1 GOF patients shared an immunometabolic phenotype of heightened glucose transporter 1 (GLUT1) and carnitine palmitoyl transferase 1A (CPT1a) expression across multiple immune cell lineages. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5294por Nguyen, Huong Thi, Gu, Mingkun, Werlinger, Pia, Cho, Joo-Hyung, Cheng, Jinhua, Suh, Joo-Won“…Moreover, administration of MJM60958 resulted in a significantly decreased expression of some genes and proteins which are related to lipid accumulation, such as fatty acid synthase (FAS), acetyl-CoA carboxylase (ACC), and sterol regulatory element-binding protein 1 (SREBP-1), and also upregulated genes and protein expression of lipid oxidation such as peroxisome proliferator-activated receptor alpha (PPARα) and carnitine palmitoyltransferase 1a (CPT1A). Administration of MJM60958 increased the relative abundance of specific microbial taxa such as Verrucomicrobia, which are abundant in non-NAFLD mice, and reduced Firmicutes, which are a major group in NAFLD mice. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5295por Yang, Jing, Chen, Lei, Shang, Xue-Ying, Chen, Yi-Lin, Zhao, Shan-Shan, Jin, Shi, Yang, Jing, Liu, Hui-Xin, Du, Jian“…Furthermore, the circulating serine, phosphatidylcholine (PC) 20:5/22:5, riboflavin, L–carnitine, and linoleic acid were evaluated after RYGB surgery. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5296por Moore, Amy, Busch, Michael P., Dziewulska, Karolina, Francis, Richard O., Hod, Eldad A., Zimring, James C., D’Alessandro, Angelo, Page, Grier P.“…We also confirmed previous metabolite GWA results for associations, including N(6)-methyl-L-lysine and protein PYROXD2 and various carnitines and transporter SLC22A16. Association between pyruvate levels and G6PD polymorphisms was validated in an independent cohort and novel murine models of G6PD deficiency (African and Mediterranean variants). …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5297“…Results: Seventeen RCTs investigating 16 drug categories, duloxetine, pregabalin, crocin, tetrodotoxin, venlafaxine, monosialotetrahexosyl ganglioside (GM1), lamotrigine, KA (ketamine and amitriptyline) cream, nortriptyline, amitriptyline, topical Citrullus colocynthis (bitter apple) oil, BAK (baclofen, amitriptyline hydrochloride, and ketamine) pluronic lecithin organogel, gabapentin, and acetyl l-carnitine (ALC), in the treatment of CIPN were retrieved. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5298por Alwadani, Ashwag H., Almasri, Soheir A., Aloud, Amal A., Albadr, Nawal A., Alshammari, Ghedeir M., Yahya, Mohammed Abdo“…Interestingly, only treatment with γ-Oryzanol stimulated the mRNA levels of proliferator-activated receptor alpha (PPARα) and carnitine palmitoyltransferase 1 (CPT1) in the liver and white adipose tissue (WAT) of rats. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5299por Russo, Giorgio Ivan, Asmundo, Maria Giovanna, Lo Giudice, Arturo, Trefiletti, Giuseppe, Cimino, Sebastiano, Ferro, Matteo, Lombardo, Riccardo, De Nunzio, Cosimo, Morgia, Giuseppe, Piombino, Eliana, Failla, Maria, Caltabiano, Rosario, Broggi, Giuseppe“…We demonstrated that ATP-lyase (odds ratio [OR]: 1.71; p < 0.01), fatty acid synthase (OR: 4.82; p < 0.01), carnitine palmitoyl transferase-1a (OR: 2.27; p < 0.05) were associated with androgen receptor (AR) expression. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
5300por Lu, Ziye, Yao, Chunfeng, Tan, Beiping, Dong, Xiaohui, Yang, Qihui, Liu, Hongyu, Zhang, Shuang, Chi, Shuyan“…Compared to both the LL-Ly group and the LP-Ly group, significantly lower liver enzyme activities and gene expression of fatty acid synthase, hormone-sensitive lipase, and carnitine palmitoyltransferase 1 were found in the Control group (P < 0.05). …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto