“…METHODS: This single-centre, pilot randomized clinical trial was conducted at the University Hospital “Maggiore della Carità” (Novara, Italy). Adult patients undergoing major cerebral or spinal neurosurgical interventions with risk index for pulmonary post-operative complications > 2 and not expected to need post-operative intensive care unit (ICU) admission were considered eligible. …”
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“…Chest radiographs were used to estimate AP/PA field size and separation at the carina; diagnostic chest CT data was imported into the treatment planning system for field size and MU calculation before patient arrival, without using the department's CT simulator. …”
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“…Out of 437 eligible patients, 183 individuals were enrolled at the Rheumatology and Hepatology Tertiary Units of “Maggiore della Carità” University Hospital in Novara: of those, 52 were healthy subjects, while among the remaining 131 patients, 30 had a diagnosis of spondyloarthritis, 25 had autoimmune hepatitis, 10 were liver transplantation recipients, 23 suffered from connective tissue diseases (including 10 cases that overlapped with other diseases), 40 were treated for rheumatoid arthritis, and 5 had vasculitis. …”
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“…Ferrajoli, Luigi, (2006) Sobre los derechos fundamentales y sus garantías, en Vázquez Valencia, Daniel, et al, (2011), Curso fundamentos teóricos de los derechos humanos, México, Comisión de Derechos Humanos del Distrito Federal. …”
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“…La crisis de salud pública ha desbordado la capacidad del sistema sanitario debido, en gran parte, a sus carencias organizativas, así como de sus sistemas de información y, sobre todo, por una gobernanza carente de coordinación y cooperación sanitaria interautonómica. …”
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“…The following 13 points constitute the consensus of the Society and have been approved by the Research Committee of the Society: Energy drinks (ED) commonly contain caffeine, taurine, ginseng, guarana, carnitine, choline, B vitamins (vitamins B1, B2, B3, B5, B6, B9, and B12), vitamin C, vitamin A (beta carotene), vitamin D, electrolytes (sodium, potassium, magnesium, and calcium), sugars (nutritive and non-nutritive sweeteners), tyrosine, and L-theanine, with prevalence for each ingredient ranging from 1.3 to 100%. …”
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“…Co-trimoxazole (CTX) is given for patients with HIV for the prophylaxis of opportunistic infection (OI), commonly for pneumocystis carinii pneumonia. It was reported that CTX was associated with a 25–46% reduction in mortality among individuals infected with HIV in sub-Saharan Africa. …”
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“…In 2/6 (33%) patients, a reconduction of the PVs (1 LIPV, 1 posterior carina on both sides) was seen. In the remaining 4/6 (67%) patients, during re-do procedure typical or atypical flutter was treated, in presence of durable PV isolation. …”
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“…Frequently required segments for PVI completion were roof and carina of LPV and roof and posterior of RPV. In most cases of control group, full circumferential ablation was required (LPV 22/27(81%) and RPV 24/27(89%)). …”
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“…Espinosa, MD, MSc, AstraZeneca: Grant/Research Support|Enanta: Grant/Research Support|Jansen and Jansen: Advisor/Consultant|Kentucky Rural Health Association: Honoraria|Merck: Grant/Research Support|Sanofi: Advisor/Consultant|Sanofi: Grant/Research Support|Sanofi: Honoraria|Sobi: Dinner Amol Purandare, MD, Caribou: Stocks/Bonds|Intellia: Stocks/Bonds|Merck: Grant/Research Support|Moderna: Grant/Research Support|Pfizer: Grant/Research Support Carina A. Rodriguez, MD, Gilead: Grant/Research Support|Moderna: Grant/Research Support|Novavax: Grant/Research Support…”
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“…The following new synonymies are established: Brachycerus obesus (Fabricius, 1775) = Curculio scalaris Fabricius, 1777, syn. n., Brachyderes lusitanicus (Fabricius, 1781) = Curculio moratus Fabricius, 1798, syn. n., Brachypera (Brachypera) crinita (Boheman, 1834) = Curculio striatus Fabricius, 1787, syn. n., Brachysomus erinaceus (Fabricius, 1802) = Brachysomus villosulus (Germar, 1824), syn. n., Bronchus abruptecostatus (Gyllenhal, 1833) = Curculio spectrum Fabricius, 1802, syn. n., Bronchus nivosus (Sparrman, 1785) = Curculio recurvus Fabricius, 1802, syn. n., Camptorhinus tibialis (Sparrman, 1785) = Rhynchaenus alienatus Fabricius, 1802, syn. n., Coelocephalapion atrirostre (Fabricius, 1802) = Coelocephalapion luteirostre (Gerstäcker, 1854), syn. n., Cyrtoderes cristatus (DeGeer, 1778) (Tenebrionidae) = Brachycerus cristatus Fabricius, 1798, syn. n., Desmidophorus hebes (Fabricius, 1781) = Curculio tuberculatus Fabricius, 1792, syn. n., Donus salviae (Schrank, 1789) = Curculio denticornis Fabricius, 1798, syn. n., Exomias holosericeus (Fabricius, 1802) = Exomias chevrolati (Boheman, 1842), syn. n., Nerthops sticticus (Fabricius, 1777) = Nerthops guttatus (Olivier, 1807), syn. n., Phyllobius oblongus (Linnaeus, 1758) = Curculio mali Fabricius, 1782, syn. n., and Rhinocyllus conicus (Froelich, 1792) = Bruchus punctatus Fabricius, 1798, syn. n. …”
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“…PARTICIPANTS/MATERIALS, SETTING, METHODS: In these blastocysts, expression of molecules involved in adiponectin signalling [adaptor protein 1 (APPL1), AMPK, acetyl-CoA carboxylase (ACC), p38 mitogen-activated protein kinases (p38 MAPK)], lipid metabolism [PPARα, cluster of differentiation 36 (CD36), fatty acid transport protein 4 (FATP4), fatty acid binding protein (FABP4), carnitine palmityl transferase 1 (CPT1), hormone-senstive lipase (HSL), lipoprotein lipase (LPL)] and members of the insulin/insulin-like growth factor (IGF)-system [IGF1, IGF2, insulin receptor (InsR), IGF1 receptor (IGF1R)] were analyzed by quantitative RT-PCR and western blot. …”
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“…There were 11 cases of conduction only in the carina area, five with left-sided and six with right-sided. …”
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“…In 4/13 (31%) patients in the X-ray group, a re-do procedure was performed, 2 patients had durable PVI with typical or atypical atrial flutter, 1 patient had reconnection of both posterior carinae and 1 patient had typical atrial flutter degenerating in AF. …”
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“…The stenosis was situated at a median distance of 3 cm [interquartile range (IQR): 0.5-7] from the true vocal cords or 7 cm (IQR: 3-9) from the carina. The median length of tracheal resection was 2 cm (IQR: 1-4). …”
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“…One-way ANOVA and Tukey HSD analyses were conducted using JMP software (JMP Pro 16 for Mac, SAS Institute, Cary, North Caronia) to determine whether there are significant differences between the predicted number of hens and the actual number of hens under various situations (i.e., age, light intensity, and observational angles). …”
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“…Abbreviations: Acadl: acyl-CoA dehydrogenase, long chain; Acadm: acyl-CoA dehydrogenase, C-4 to C-12 straight chain; AIF: apoptosis-inducing factor; Akt: protein kinase B (PKB); AMPK: AMP-activated protein kinase; ATF-4: activating transcription factor 4; ATM: ATM serine/threonine kinase; Bax: BCL2 associated X, apoptosis regulator; Bcl-2: B cell Leukemia/Lymphoma 2 apoptosis regulator; Bhlhe40: basic helix-loop-helix family member e40; BH3: Borane; Bim: bcl-2 interacting mediator of cell death; Bok: Bcl-2 related ovarian killer; COX-IV: cytochrome c oxidase IV; cGMP: Cyclic guanosine monophosphate; c-myc: proto-oncogene protein; Cpt1b: carnitine palmitoyltransferase 1B; Dr5: death receptor 5; eNOS: endothelial nitric oxide synthase; ERK: extracellular regulated MAP kinase; Fas: Fas Cell surface death receptor; FDXR: Ferredoxin Reductase; FOXO3a: forkhead box O3; Gadd45a: growth arrest and DNA damage-inducible 45 alpha; GLS2: glutaminase 2; GLUT 1 and 4: glucose transporter 1(endothelial) and 4 (skeletal muscle); GSH: Glutathione; Hes1: hes family bHLH transcription factor 1; Hey1: hes related family bHLH transcription factor with YRPW motif 1; HIFI-α: hypoxia-inducible factor 1, α-subunit; HK2: Hexokinase 2; HSP70: Heat Shock Protein 70; H(2)O(2): Hydrogen Peroxide; Id2: inhibitor of DNA-binding 2; IGF-1-BP3: Insulin-like growth factor binding protein 3; IL-1β: Interleukin 1 beta; iNOS: inducible nitric oxide synthase; IRS-1: Insulin receptor substrate 1; JNK: c-Jun N-terminal kinases; LY-83583: 6-anilino-5,8-quinolinedione; inhibitor of soluble guanylate cyclase and of cGMP production; Mdm 2/ 4: Mouse double minute 2 homolog (mouse) Mdm4 (humans); mtDNA: mitochondrial DNA; MURF1: Muscle RING-finger protein-1; MyoD: Myogenic differentiation 1; MyoG: myogenin; Nanog: Nanog homeobox; NF-kB: Nuclear factor-κB; NO: nitric oxide; NoxA: phorbol-12-myristate-13-acetate-induced protein 1 (Pmaip1); NRF-1: nuclear respiratory factor 1; Nrf2: Nuclear factor erythroid 2-related factor 2; P21: Cdkn1a cyclin-dependent kinase inhibitor 1A (P21); P38 MAPK: mitogen-activated protein kinases; p53R2: p53 inducible ribonucleotide reductase gene; P66Shc: src homology 2 domain-containing transforming protein C1; PERP: p53 apoptosis effector related to PMP-22; PGC-1α: Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGM: phosphoglucomutase; PI3K: Phosphatidylinositol-4,5-bisphosphate 3-kinase; PKCβ: protein kinase c beta; PTEN: phosphatase and tensin homolog; PTIO: 2-phenyl-4, 4, 5, 5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIO) has been used as a nitric oxide (NO) scavenger; Puma: The p53 upregulated modulator of apoptosis; PW1: paternally expressed 3 (Peg3); RNS: Reactive nitrogen species; SIRT1: sirtuin 1; SCO2: cytochrome c oxidase assembly protein; SOD2: superoxide dismutase 2; Tfam: transcription factor A mitochondrial; TIGAR: Trp53 induced glycolysis repulatory phosphatase; TNF-a: tumor necrosis factor a; TRAF2: TNF receptor associated factor 2; TRAIL: type II transmembrane protein.…”
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“…PV gaps were located at anterior (31.3%), posterior (31%), and carina (16%) sites after the FPI evaluation. At successful ablation spots, both baseline LI and LI drop were larger than at PV gap spots (161.4Ω vs 153.0Ω, p<0.0001 for baseline LI; 22.1Ω vs 14.4Ω, p<0.0001 for LI drop), whereas RF delivery time was shorter (9.1s at successful ablation spots vs 10.1s at PV gap spots, p<0.0001). …”
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“…DISCLOSURES: Osamu Matsuoka, MD, Sanofi Pasteur (Scientific Research Study Investigator, Research Grant or Support) Mugen Ujiie, MD, Sanofi Pasteur (Scientific Research Study Investigator, Research Grant or Support) Hitoshi Kikuchi, MD, Sanofi Pasteur (Scientific Research Study Investigator)Sanofi Pasteur (Research Grant or Support) Danaya Chansinghakul, MD, Sanofi Pasteur (Employee) Takahiro Inoue, MSc, Sanofi Pasteur (Employee) Kucku Varghese, PhD, Sanofi Pasteur (Employee) Nuchra Sirisuphmitr, MSc, Sanofi Pasteur (Employee) Tomoyuki Hashiguchi, MSc, Sanofi Pasteur (Employee) Betzana Zambrano, MD, Sanofi Pasteur (Employee) Takahiro Nakama, MD, Sanofi Pasteur (Employee) Carina Frago, MD, Sanofi Pasteur (Employee, Shareholder) Emilia Jordanov, MD, Sanofi Pasteur (Employee, Shareholder) Mandeep S. …”
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“…Batista, BSc, MSD Brazil (Employee) Fernando Serra, MD, MSD Brazil (Employee) Cintia Parellada, MD, PhD, MSD Brazil (Employee) Guilherme Julian, BSc, MSc, IQVIA (Employee)MSD (Consultant, Research Grant or Support) Karina Nakajima, BSc, PhD, IQVIA (Employee)MSD (Consultant, Research Grant or Support) Thais Moreira, MD, MSc, MSD Brazil (Employee)…”
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