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601por Ghanta, Mohankrishna, Panchanathan, Elango, Lakkakula, Bhaskar Venkata Kameswara Subrahmanya, Narayanaswamy, Anbumani, Abhinand, P.A., Antony, Stalin“…It is of interest to evaluate the pharmacological activity of Momordica charantia phytoconstituent (DGalacturonic acid) and ODQ with catalytic domain of sGC enzyme, using Autodock version 4.2 programs. …”
Publicado 2018
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602por Todeschini, Cristina C., Parizotto, José L. B., Guzman, Frank, Zanella, Camila M., Margis, Rogério, Goetze, Márcia, Paggi, Gecele M., Santana Costa, Laís M., de Aguiar Melo, Camila, Hirsch, Luiza D., Bered, Fernanda“…PREMISE OF THE STUDY: Expressed sequence tag–simple sequence repeat (EST‐SSR) markers were isolated for Vriesea carinata, an endemic bromeliad from the Brazilian Atlantic Forest. …”
Publicado 2018
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603por Park, Namhyeon, Nguyen, Thi Thanh Hanh, Lee, Gang‐Hee, Jin, Shi‐Na, Kwak, So‐Hyung, Lee, Tae‐Kyung, Choi, Yeong‐Hwan, Kim, Seong‐Bo, Kimura, Atsuo, Kim, Doman“…In order to improve the quality and functionality of Makgeolli, the Rhizopus oligosporus fermented buckwheat containing 18.7 mg/kg of l‐carnitine were utilized to brew l‐carnitine fortified Makgeolli with rice. …”
Publicado 2018
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604por Cao, Bing, Wang, Dongfang, Pan, Zihang, Brietzke, Elisa, McIntyre, Roger S., Musial, Natalie, Mansur, Rodrigo B., Subramanieapillai, Mehala, Zeng, Jing, Huang, Ninghua, Wang, Jingyu“…Subjects with schizophrenia have high risks of metabolic abnormalities and bioenergetic dysfunction. Acyl-carnitines involved in bioenergetic pathways provide potential biomarker targets for identifying early changes and onset characteristics in subjects with schizophrenia. …”
Publicado 2019
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605por Rattray, Nicholas J. W., Trivedi, Drupad K., Xu, Yun, Chandola, Tarani, Johnson, Caroline H., Marshall, Alan D., Mekli, Krisztina, Rattray, Zahra, Tampubolon, Gindo, Vanhoutte, Bram, White, Iain R., Wu, Frederick C. W., Pendleton, Neil, Nazroo, James, Goodacre, Royston“…Our study provides evidence that the dysregulation of carnitine shuttle and vitamin E pathways play a role in the risk of frailty.…”
Publicado 2019
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606por Mei, Zi, Zhang, Kai, Lam, Alfred King‐Yin, Huang, Junwen, Qiu, Feng, Qiao, Bin, Zhang, YiEnlace del recurso
Publicado 2019
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607por Cherix, Antoine, Larrieu, Thomas, Grosse, Jocelyn, Rodrigues, João, McEwen, Bruce, Nasca, Carla, Gruetter, Rolf, Sandi, Carmen“…Energy metabolic changes in the nucleus accumbens (NAc) were recently related to hierarchical status and vulnerability to develop depression-like behavior. Acetyl-L-carnitine (LAC), a mitochondria-boosting supplement, has shown promising antidepressant-like effects opening therapeutic opportunities for restoring energy balance in depressed patients. …”
Publicado 2020
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608por Kesari, Pooja, Pratap, Shivendra, Dhankhar, Poonam, Dalal, Vikram, Mishra, Manisha, Singh, Pradyumna Kumar, Chauhan, Harsh, Kumar, Pravindra“…Momordica charantia (Mc) seeds are widely used edible crop with high nutritional quality. …”
Publicado 2020
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609por Hulme, Heather, Meikle, Lynsey M., Strittmatter, Nicole, van der Hooft, Justin J. J., Swales, John, Bragg, Ryan A., Villar, Victor H., Ormsby, Michael J., Barnes, Stephanie, Brown, Sheila L., Dexter, Alex, Kamat, Maya T., Komen, Jasper C., Walker, Daniel, Milling, Simon, Osterweil, Emily K., MacDonald, Andrew S., Schofield, Chris J., Tardito, Saverio, Bunch, Josephine, Douce, Gillian, Edgar, Julia M., Edrada-Ebel, RuAngelie, Goodwin, Richard J. A., Burchmore, Richard, Wall, Daniel M.“…We demonstrate that these compounds are produced by anaerobic commensal bacteria from the family Lachnospiraceae (Clostridiales) family, colocalize with carnitine in brain white matter, and inhibit carnitine-mediated fatty acid oxidation in a murine cell culture model of central nervous system white matter. …”
Publicado 2020
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610por Grünert, Sarah C., Tucci, Sara, Schumann, Anke, Schwendt, Meike, Gramer, Gwendolyn, Hoffmann, Georg F., Erbel, Michelle, Stiller, Brigitte, Spiekerkoetter, Ute“…CONCLUSION: As L-carnitine supplementation can prevent and mostly reverse clinical symptoms of primary carnitine deficiency, all patients with cardiomyopathy should be investigated for primary carnitine deficiency even if newborn screening results were unremarkable.…”
Publicado 2020
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611por Gao, Ya, Chen, Jian-Chao, Peng, Xing-Rong, Li, Zhong-Rong, Su, Hai-Guo, Qiu, Ming-Hua“…ABSTRACT: Ten cucurbitane-type triterpene glycosides, including five new compounds named charantosides H (1), J (2), K (3), momorcharacoside A (4), goyaglycoside-l (5), and five known compounds (6–10), were isolated from the EtOAc extract of Momordica charantia fruits. The chemical structures of these compounds were identified by 1D and 2D NMR and HRESIMS spectroscopic analyses. …”
Publicado 2020
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612“…The L-carnitine could be an option for treatment of MHD patients.…”
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613“…There are accumulating evidences showing the anti-inflammatory activity of Momordica charantia. However, the effects of M. charantia on inflammatory response and glucose metabolism in activated macrophages have not been fully established. …”
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614L-carnitine infusion does not alleviate lipid-induced insulin resistance and metabolic inflexibilitypor Bruls, Yvonne M. H., op den Kamp, Yvo J. M., Phielix, Esther, Lindeboom, Lucas, Havekes, Bas, Schaart, Gert, Moonen-Kornips, Esther, Wildberger, Joachim E., Hesselink, Matthijs K. C., Schrauwen, Patrick, Schrauwen-Hinderling, Vera B.“…BACKGROUND: Low carnitine status may underlie the development of insulin resistance and metabolic inflexibility. …”
Publicado 2020
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615por Varney, Jessica Lyn, Fowler, Jason William, McClaughry, Trenda Clarice, Vignale, Karen, Caldas, Justina, Weil, Jordan Taylor, Coon, Craig Nelson“…L‐Carnitine is critical for protection against bioaccumulation, long‐chain fatty acid transportation and energy production. …”
Publicado 2020
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616por Mohammadmoradi, Shayan, Howatt, Deborah A, Lu, Hong S, Daugherty, Alan, Saha, Sibu P“…Bitter melon (BM; Momordica charantia L.) has been reported to ameliorate diet-induced obesity and dyslipidemia. …”
Publicado 2020
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617por G. Tsadik, Yordanos Kiros, Hailu, Abrha Mulu, Asfaw, Seyoum Leta, Mekonnen, Yedilfana Setarge“…Besides, it remarkably increased the dry weight of the edible part of Brassica carinata by 228%. The results revealed that BSB is very effective additive in cadmium immobilization, in turn, significantly (p-value = 0.00) promoting vegetable (Brassica carinata) growth. …”
Publicado 2020
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618“…BACKGROUND: L-carnitine mediates the utilization of fatty acids and glucose in the myocardium. …”
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619por Verkerk, Arie O., Knottnerus, Suzan J. G., Portero, Vincent, Bleeker, Jeannette C., Ferdinandusse, Sacha, Guan, Kaomei, IJlst, Lodewijk, Visser, Gepke, Wanders, Ronald J. A., Wijburg, Frits A., Bezzina, Connie R., Mengarelli, Isabella, Houtkooper, Riekelt H.“…In the fatty acid oxidation process, carnitine is required for bidirectional transport of acyl groups across the mitochondrial membrane. …”
Publicado 2021
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620por Ardizzone, Alessio, Fusco, Roberta, Casili, Giovanna, Lanza, Marika, Impellizzeri, Daniela, Esposito, Emanuela, Cuzzocrea, Salvatore“…The ultra-micronized formulation of PEA (um-PEA), that has an enhanced rate of dissolution, is extensively used. Acetyl-l-carnitine (LAC), employed for the treatment of neuropathic pain in humans, is able to cause analgesia by up-regulating type-2 metabotropic glutamate (mGlu2) receptors. …”
Publicado 2021
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