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661por Jing, Zheng, Iba, Tomohiro, Naito, Hisamichi, Xu, Pingping, Morishige, Jun-ichi, Nagata, Naoto, Okubo, Hironao, Ando, Hitoshi“…Co-administration of L-carnitine in rats treated with lenvatinib for 2 weeks completely prevented the decrease in carnitine content and expression levels of carnitine-related and OXPHOS proteins, including carnitine/organic cation transporter 2, in the skeletal muscle. …”
Publicado 2023
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662por Nuchtavorn, Nantana, Leanpolchareanchai, Jiraporn, Visansirikul, Satsawat, Bunsupa, Somnuk“…The developed methods were successfully utilized to extract and quantify charantin from M. charantia fruit powder and herbal products. Moreover, these methods are rapid (<10 min), inexpensive, simple, reproducible, and environmentally friendly.…”
Publicado 2023
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663“…The objective of this investigation was to find out whether L-carnitine-loaded nanoparticle (LCn) could reduce the reproductive toxicity of cypermethrin (CYP), the widely used insecticide in veterinary medicine in male rats. …”
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664por Zhu, Yaqin, Wang, Yue, Li, Ying, Li, Zhongqi, Kong, Wenhui, Zhao, Xiaoxuan, Chen, Shuting, Yan, Liting, Wang, Lenan, Tong, Yunli, Shao, Huanjie“…Previously, our study showed that carnitine palmitoyltransferase 1A (CPT1A) is highly expressed in ovarian cancer cells and promotes the development of ovarian cancer. …”
Publicado 2023
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665por Juncker, Hannah G., van den Akker, Chris H. P., Meerdink, Pauline L., Korosi, Aniko, Vaz, Frédéric M., van Goudoever, Johannes B., van Keulen, Britt J.“…Two important nutrients, vitamin B2 and carnitine, are mostly ingested via animal products. …”
Publicado 2023
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666“…There is a lot of evidence showing that carnitine deficiency is linked to fatigue development and severity in some conditions. …”
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667“…Objective: Cognitive impairment is one of the core symptoms of schizophrenia, which is stable and lifelong. L-carnitine has been shown to improve cognitive function and decrease the rate of cognitive deterioration in patients with Alzheimer’s disease. …”
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668por Stevenson Naïtchédé, Labodé Hospice, Nyende, Aggrey Bernard, Runo, Steven, Borlay, Allen Johnny“…Bitter melon (Momordica charantia L.), a widely cultivated food and medicinal plant native to the world's subtropics and tropics, is a Cucurbitaceae rich in carotenoids. …”
Publicado 2023
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669“…Inappropriate hepatic lipogenesis, hypertriglyceridaemia, decreased fatty acid oxidation and muscle protein wasting are common in patients with sepsis, cancer or AIDS. Given carnitine's role in the oxidation of fatty acids (FAs), we anticipated that carnitine might promote FA oxidation, thus ameliorating metabolic disturbances in lipopolysaccharide (LPS)- and methylcholanthrene-induced sarcoma models of wasting in rats. …”
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670“…Therefore we sought to determine the effects of acetyl L-carnitine arginate (ALCA) on resting and postprandial biomarkers of glucose and lipid metabolism, as well as oxidative stress. …”
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671“…BACKGROUND: Escalating trends of obesity and associated type 2 diabetes (T2D) has prompted an increase in the use of alternative and complementary functional foods. Momordica charantia or bitter melon (BM) that is traditionally used to treat diabetes and complications has been demonstrated to alleviate hyperglycemia as well as reduce adiposity in rodents. …”
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672por Siegner, Ralf, Heuser, Stefan, Holtzmann, Ursula, Söhle, Jörn, Schepky, Andreas, Raschke, Thomas, Stäb, Franz, Wenck, Horst, Winnefeld, Marc“…To investigate how natural substances influence these two processes, we examined the effects of lotus leaf extract (Nelumbo nucifera-extract solution obtained from Silab, France) and L-carnitine on human preadipocytes and adipocytes. METHODS: For our in vitro studies, we used a lotus leaf extract solution alone or in combination with L-carnitine. …”
Publicado 2010
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673“…This study examined whether carnitine deficiency and oxidative stress, secondary to Fanconi Syndrome, provoke IFO-induced cardiomyopathy as well as exploring if carnitine supplementation using Propionyl-L-carnitine (PLC) could offer protection against this toxicity. …”
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674“…In this work, we report on the neuroprotective, antiapoptotic and antioxidant action of a natural substance, -carnitine. This compound is known for its ability to improve the mitochondrial performance. …”
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675por Nerurkar, Pratibha V, Johns, Lisa M, Buesa, Lance M, Kipyakwai, Gideon, Volper, Esther, Sato, Ryuei, Shah, Pranjal, Feher, Domonkos, Williams, Philip G, Nerurkar, Vivek R“…The objective of our study was to investigate the neuroprotective effects of Momordica charantia (bitter melon) on high-fat diet (HFD)-associated BBB disruption, stress and neuroinflammatory cytokines. …”
Publicado 2011
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676“…Transient carnitine transport defect is a rare condition in newborns reported in 1/90,000 live births. …”
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677“…Momordica charantia (bitter gourd) has been used in the traditional system of medicine for the treatment of various diseases. …”
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678“…PURPOSE: Hypoxic-ischemic encephalopathy is an important cause of neonatal mortality, as this brain injury disrupts normal mitochondrial respiratory activity. Carnitine plays an essential role in mitochondrial fatty acid transport and modulates excess acyl coenzyme A levels. …”
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679por Muralidharan, Arumugam Ramachandran, Leema, George, Annadurai, Thangaraj, Anitha, Thirugnanasambandhar Sivasubramanian, Thomas, Philip A., Geraldine, Pitchairaj“…PURPOSE: To determine the putative role of acetyl-L-carnitine (ALCAR) in maintaining normal intercellular communication in the lens through connexin. …”
Publicado 2012
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680por Huang, Hongbiao, Liu, Ningning, Guo, Haiping, Liao, Siyan, Li, Xiaofen, Yang, Changshan, Liu, Shouting, Song, Wenbin, Liu, Chunjiao, Guan, Lixia, Li, Bing, Xu, Li, Zhang, Change, Wang, Xuejun, Dou, Q. Ping, Liu, Jinbao“…L-carnitine (LC) is generally believed to transport long-chain acyl groups from fatty acids into the mitochondrial matrix for ATP generation via the citric acid cycle. …”
Publicado 2012
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