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861por Lee, Joanna Jinling, Saiful Yazan, Latifah, Kassim, Nur Kartinee, Che Abdullah, Che Azurahanim, Esa, Nurulaidah, Lim, Pei Cee, Tan, Dai Chuan“…Christia vespertilionis, commonly known as ‘Daun Rerama’, has recently garnered attention from numerous sources in Malaysia as an alternative treatment. …”
Publicado 2020
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862“…Methods: A wide carnitine coverage MSI method was developed to investigate the spatial alternations of carnitines in cancer tissues of xenograft mouse models and human samples. …”
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863por Gong, Li-li, Yang, Song, Zhang, Wen, Han, Fei-fei, Xuan, Ling-ling, Lv, Ya-li, Liu, He, Liu, Li-hong“…We discovered two carnitine metabolites including hydroxydecanoyl carnitine and methylglutarylcarnitine. …”
Publicado 2020
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864por Nakanishi, Hiroyuki, Hayakawa, Yuka, Kubota, Youhei, Kurosaki, Masayuki, Osawa, Leona, Inada, Kento, Kirino, Sakura, Yamashita, Koji, Sekiguchi, Shuhei, Okada, Mao, Wan, Wang, Higuchi, Mayu, Takaura, Kenta, Maeyashiki, Chiaki, Kaneko, Shun, Tamaki, Nobuharu, Yasui, Yutaka, Noda, Takamasa, Nakanishi, Kaoru, Tsuchiya, Kaoru, Itakura, Jun, Takahashi, Yuka, Izumi, Namiki“…To evaluate the effects of l-carnitine on impaired brain function in patients with liver cirrhosis. …”
Publicado 2020
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865por Nguyen, Dai Hai, Vo, Thanh Nguyet Nguyen, Nguyen, Ngoc Tung, Ching, Yern Chee, Hoang Thi, Thai Thanh“…In this study, Momordica charantia and Psidium guajava leaf extract (MC.broth and PG.broth) are exploited to fabricate two kinds of biogenic silver nanoparticles (MC.AgNPs and PG.AgNPs). …”
Publicado 2020
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866por Lagatie, Ole, Verheyen, Ann, Van Asten, Stijn, Odiere, Maurice R., Djuardi, Yenny, Levecke, Bruno, Vlaminck, Johnny, Mekonnen, Zeleke, Dana, Daniel, T’Kindt, Ruben, Sandra, Koen, van Outersterp, Rianne, Oomens, Jos, Lin, Ronghui, Dillen, Lieve, Vreeken, Rob, Cuyckens, Filip, Stuyver, Lieven J.“…Here we describe how metabolome analysis was used to identify the A. lumbricoides-specific urine biomarker 2-methyl pentanoyl carnitine (2-MPC). This biomarker was found to be 85.7% accurate in determining infection and 90.5% accurate in determining a moderate-to-heavy infection. …”
Publicado 2020
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867“…Primary carnitine deficiency (PCD) is a disorder of the carnitine cycle that results in defective fatty acid oxidation. …”
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868por Lin, Yiming, Lin, Weihua, Chen, Yanru, Lin, Chunmei, Zheng, Zhenzhu, Zhuang, Jianlong, Fu, Qingliu“…BACKGROUND: Primary carnitine deficiency (PCD) is an autosomal recessive disorder affecting the carnitine cycle and resulting in defective fatty acid oxidation. …”
Publicado 2020
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869l-Carnitine ameliorates congenital myopathy in a tropomyosin 3 de novo mutation transgenic zebrafishpor Hsu, Po-Jui, Wang, Horng-Dar, Tseng, Yung-Che, Pan, Shao-Wei, Sampurna, Bonifasius Putera, Jong, Yuh-Jyh, Yuh, Chiou-Hwa“…With RNAseq transcriptomic analysis of the expression profiling from the muscle specimens, it surprisingly discloses large downregulation of genes involved in pathways of sodium, potassium, and calcium channels, which can be rescued by l-carnitine treatment, fatty acid metabolism was differentially dysregulated in TPM3(E151G) fish and rescued by l-carnitine treatment. …”
Publicado 2021
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870“…However, compared with other species, the success rates of in vitro embryo production (IVEP) in dogs are low. L-Carnitine (LC) is a small water-soluble molecule; it plays an essential role in fatty acid metabolism and acts as a potent antioxidant. …”
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871por Savic, Dragana, Ball, Vicky, Curtis, M. Kate, Sousa Fialho, Maria da Luz, Timm, Kerstin N., Hauton, David, West, James, Griffin, Julian, Heather, Lisa C., Tyler, Damian J.“…One factor contributing to the metabolic dysfunction in diabetes may be abnormal handling of acetyl and acyl groups by the mitochondria. L-carnitine is responsible for their transfer across the mitochondrial membrane, therefore, supplementation with L-carnitine may provide a route to improve the metabolic state of the diabetic heart. …”
Publicado 2021
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872por , Mahwish, Saeed, Farhan, Sultan, M. Tauseef, Riaz, Ayesha, Ahmed, Sagheer, Bigiu, Nicusor, Amarowicz, Ryszard, Manea, RosanaEnlace del recurso
Publicado 2021
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873por Ueno, Yuji, Saito, Asami, Nakata, Junichiro, Kamagata, Koji, Taniguchi, Daisuke, Motoi, Yumiko, Io, Hiroaki, Andica, Christina, Shindo, Atsuhiko, Shiina, Kenta, Miyamoto, Nobukazu, Yamashiro, Kazuo, Urabe, Takao, Suzuki, Yusuke, Aoki, Shigeki, Hattori, Nobutaka“…Although l-carnitine alleviated white-matter lesions in an experimental study, the treatment effects of l-carnitine on white-matter microstructural damage and cognitive decline in hemodialysis patients are unknown. …”
Publicado 2021
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874por Bellamine, Aouatef, Pham, Tram N. Q., Jain, Jaspreet, Wilson, Jacob, Sahin, Kazim, Dallaire, Frederic, Seidah, Nabil G., Durkee, Shane, Radošević, Katarina, Cohen, Éric A.“…These data suggest that L-carnitine tartrate should be tested with appropriate trials in humans for the possibility to limit SARS-CoV-2 infection.…”
Publicado 2021
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875“…The L-carnitine biosynthesis pathway has not been observed in prokaryotes, and the use of eukaryotic microorganisms as natural L-carnitine producers lacks economic viability due to complex cultivation and low titers. …”
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876por Meisel, Peter, Pagels, Stefanie, Grube, Markus, Jedlitschky, Gabriele, Völzke, Henry, Kocher, ThomasEnlace del recurso
Publicado 2020
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877“…There are prominent gaps in our understanding of how TMA is produced from the essential dietary nutrient l-carnitine, particularly in the anoxic environment of the human gut where oxygen-dependent l-carnitine–metabolizing enzymes are likely inactive. …”
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878por Maina, Sylvia, Ryu, Da Hye, Cho, Jwa Yeong, Jung, Da Seul, Park, Jai-Eok, Nho, Chu Won, Bakari, Gaymary, Misinzo, Gerald, Jung, Je Hyeong, Yang, Seung-Hoon, Kim, Ho-Youn“…The effect of salt treatment on Brassica carinata (BC) microgreens grown under different light wavelengths on glucosinolates (GLs) and phenolic compounds were evaluated. …”
Publicado 2021
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879por Magi, Simona, Preziuso, Alessandra, Piccirillo, Silvia, Giampieri, Francesca, Cianciosi, Danila, Orciani, Monia, Amoroso, Salvatore“…Here, we induced an AD-like phenotype by using the glycolysis inhibitor glyceraldehyde (GA) and explored whether L-carnitine (4-N-trimethylamino-3-hydroxybutyric acid, LC) could mitigate neuronal damage, both in SH-SY5Y neuroblastoma cells and in rat primary cortical neurons. …”
Publicado 2021
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880por Arif, Rawaba, Ahmad, Sajjad, Mustafa, Ghulam, Mahrosh, Hafiza Salaha, Ali, Muhammad, Tahir ul Qamar, Muhammad, Dar, Hafiza Rabia“…The drugs contemporarily used for diabetes have many inevitable side effects, and many of them have become less responsive to this multifactorial disorder. Momordica charantia commonly known as bitter gourd has many bioactive compounds with antidiabetic properties. …”
Publicado 2021
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