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  1. 1041
    “…Liver biopsy showed the lesions to be well-differentiated neuroendocrine tumors, grade G1. (68)Gallium-exendin-4 positron emission tomography/CT confirmed the origin as the lesion located at the jejunum. …”
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    Rare malignant insulinoma with multiple liver metastases derived from ectopic pancreas: 3-year follow-up and literature review
  2. 1042
    “…Following GTT protocol optimization the effect of exendin‐4 and metformin was equivalent in both sexes, with females showing a more modest but more reproducible GTT response. …”
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    The glucose tolerance test in mice: Sex, drugs and protocol
  3. 1043
    por Freinet, C.
    Publicado 2019
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    La escuela popular moderna: Guía práctica para la organización material, técnica y pedagógica de la escuela popular
  4. 1044
    “…(family Papaveraceae), commonly known as greater celandine or tetterwort, has been reported to have antibacterial and anticancer effects and chelidonine is known as a functional metabolite extracted from C.…”
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    Chelidonine Induces Caspase-Dependent and Caspase-Independent Cell Death through G(2/M) Arrest in the T98G Human Glioblastoma Cell Line
  5. 1045
    “…Furthermore, mice treated with exendin-4 (30 μg/kg SC BID) after 4 months of diet were explored before and 14 days post-treatment with multimodal CMR. …”
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    Time course of cardiometabolic alterations in a high fat high sucrose diet mice model and improvement after GLP-1 analog treatment using multimodal cardiovascular magnetic resonance
  6. 1046
    por Velikyan, Irina, Eriksson, Olof
    Publicado 2020
    “…In the light of theranostics/radiotheranostics and prospective of personalized medicine in diabetes and oncology, this review presents prior and current advances in the development of radiolabeled imaging and radiotherapeutic exendin-based agents targeting glucagon-like peptide-1 receptor. …”
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    Advances in GLP-1 receptor targeting radiolabeled agent development and prospective of theranostics
  7. 1047
    “…Imeglimin enhanced GSIS in an additive manner with GLP‐1, but not with GIP, in mouse islets. Exendin‐9 had only a minor inhibitory effect on the glucose‐lowering action of imeglimin during the OGTT in KK‐Ay mice. …”
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    Stimulatory effect of imeglimin on incretin secretion
  8. 1048
    “…METHODS: LDLR-KO mice were randomly treated with normal saline, liraglutide, or liraglutide plus a GLP-1R antagonist exendin-9 for four weeks. In parallel, HUVECs were cultured with ox-LDL alone or combined with liraglutide, in the presence or absence of lectin-like ox-LDL receptor-1(LOX-1) overexpression or GLP-1R knockdown. …”
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    Liraglutide ameliorates oxidized LDL-induced endothelial dysfunction by GLP-1R-dependent downregulation of LOX-1-mediated oxidative stress and inflammation
  9. 1049
    “…RESEARCH DESIGN AND METHODS— Awake free-moving mice were infused with the GLP-1 receptor agonist exendin-4 (Ex4) into the lateral ventricle of the brain in the basal state or during hyperinsulinemic eu-/hyperglycemic clamps. …”
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    Brain Glucagon-Like Peptide-1 Regulates Arterial Blood Flow, Heart Rate, and Insulin Sensitivity
  10. 1050
    “…Simultaneous bath perfusion of 5 nM GLP-1 plus 100 nM Exendin (9-39), a GLP-1 receptor antagonist, was unable to block the GLP-1-induced increase in I(Ca); however, the increase in I(Ca )was abolished if Exendin (9-39) was pre-applied 5 min prior to GLP-1 administration. …”
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    Glucagon-like peptide-1 enhances cardiac L-type Ca(2+ )currents via activation of the cAMP-dependent protein kinase A pathway
  11. 1051
    “…Receptor selectivity was tested by the simultaneous presence of a GLP1 receptor antagonist (exendin (9-39) amide) or a VIP receptor antagonist (hybrid of neurotensin 6-11 and VIP 7-28). …”
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    Glucagon-like peptides 1 and 2 and vasoactive intestinal peptide are neuroprotective on cultured and mast cell co-cultured rat myenteric neurons
  12. 1052
    “…This sensitizing action of exendin-4 is diminished by an inhibitor of PKA (H-89) or by overexpression of dominant negative Epac. …”
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    A cAMP and Ca(2+) coincidence detector in support of Ca(2+)-induced Ca(2+) release in mouse pancreatic β cells
  13. 1053
    “…After optimization of exposure conditions, positive (exendin-4, glibenclamide) and negative (diazoxide) control compounds for acute insulin secretion responses were tested and those with the most profound effects were selected to allow potency estimations and ranking of pollutants. …”
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    Evaluation of the INS-1 832/13 Cell Line as a Beta-Cell Based Screening System to Assess Pollutant Effects on Beta-Cell Function
  14. 1054
    “…BACKGROUND: It has been reported that GLP-1 agonist exenatide (exendin-4) decreases blood pressure. The dose-dependent vasodilator effect of exendin-4 has previously been demonstrated, although the precise mechanism is not thoroughly described. …”
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    Exenatide induces aortic vasodilation increasing hydrogen sulphide, carbon monoxide and nitric oxide production
  15. 1055
    “…MK-0626 treatment restored the expression of GLP-1R, and direct administration of exendin-4 to isolated islets reduced TAC-induced cell death and 8-OHdG expression. …”
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    Dipeptidyl Peptidase IV Inhibitor MK-0626 Attenuates Pancreatic Islet Injury in Tacrolimus-Induced Diabetic Rats
  16. 1056
    “…In contrast to this model, here we demonstrate that glucagon-like peptide-1 receptor can be activated by N-terminally truncated glucagon-like peptide-1 or exendin-4 when fused to the receptor, raising the question regarding the role of N-terminal residues of peptide hormone in glucagon-like peptide-1 receptor activation. …”
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    An intrinsic agonist mechanism for activation of glucagon-like peptide-1 receptor by its extracellular domain
  17. 1057
    “…OBJECTIVE: To validate the beneficial GLP-1 mediated cardiometabolic effects post VSG using GLP-1 antagonist (exendin 9-39) in Zucker diabetic fatty rats. METHODS: Animals were divided into three (n = 5) groups: (i) sham, (ii) VSG, and (iii) VSG received exendin 9–39 (GLP-1 receptor antagonist). …”
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    Selective beneficial cardiometabolic effects of vertical sleeve gastrectomy are predominantly mediated through glucagon-like peptide (GLP-1) in Zucker diabetic fatty rats
  18. 1058
    por Zheng, Haiya, Lan, Jun, Li, Jinmei, Lv, Leili
    Publicado 2018
    “…Besides that, intraperitoneal injection of exendin-(9–39) was performed at day 1 and 4 after model construction. …”
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    Therapeutic effect of berberine on renal ischemia-reperfusion injury in rats and its effect on Bax and Bcl-2
  19. 1059
    “…RESULTS: In the present study, GLP-1 receptor antagonist (exendin-3) abolished the protective effects of DPP-4 inhibitor (sitagliptin) on right ventricular systolic pressure (RVSP) and pulmonary vascular remodeling (PVR) in monocrotaline (MCT, 60 mg/kg)-induced PH in rat. …”
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    Glucagon-like peptide-1 (GLP-1) mediates the protective effects of dipeptidyl peptidase IV inhibition on pulmonary hypertension
  20. 1060
    “…In the present study, we adopted single high-dose (60 mg/kg, i.p.) streptozotocin (STZ) to model diabetes mellitus (DM) and randomly assigned short-tail (SD) rats to a normal group, a diabetic group, GLP1 groups (50 μg/kg, 100 μg/kg, and 200 μg/kg), a GLP1 (200 μg/kg) with exendin (9-39) group, and a GLP1 with LY294002 group. …”
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    A New Way for Beta Cell Neogenesis: Transdifferentiation from Alpha Cells Induced by Glucagon-Like Peptide 1
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