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  1. 1101
    por Gallwitz, Baptist
    Publicado 2015
    “…Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) were introduced for type 2 diabetes therapy nearly 10 years ago, among them short-acting compounds on the basis of the GLP-1-like peptide exendin-4 (exenatide and lixisenatide) and a long-acting GLP-1 RA based on the human GLP-1 sequence (liraglutide). …”
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    GLP-1 Receptor Agonists in Type 2 Diabetes and Beyond – New Insights 2015
  2. 1102
    “…These changes were prevented by treatment with a neuroprotective drug, a glucagon-like peptide-1 (GLP1) receptor agonist, exendin-4 (EX-4).…”
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    Structural Changes Observed in the Piriform Cortex in a Rat Model of Pre-motor Parkinson’s Disease
  3. 1103
    “…We focus our research on the strategies that have been successfully applied to improve the plasma half-life of exendin-4, a clinically available toxin-derived anti-diabetic peptide drug.…”
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    Drug Delivery Strategies for Enhancing the Therapeutic Efficacy of Toxin-Derived Anti-Diabetic Peptides
  4. 1104
    por Maeng, Jeehye, Lee, Kyunglim
    Publicado 2022
    “…Some CPPs have been applied for the delivery of peptide antidiabetics, including insulin and exendin-4, for treating diabetes and Alzheimer’s disease. …”
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    Systemic and brain delivery of antidiabetic peptides through nasal administration using cell-penetrating peptides
  5. 1105
    “…The results demonstrated that the two polymer films displayed well-defined redox peaks in pairs during the p-type doping, and showed distinct color change from dark gray blue to light green for P(TBT-TBTh) with the band gap of 1.51 eV, and from gray blue to celandine green for P(TBT-F-TBTh) with the band gap of 1.58 eV. …”
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    Effects of Fluoro Substitution on the Electrochromic Performance of Alternating Benzotriazole and Benzothiadiazole-Based Donor–Acceptor Type Copolymers
  6. 1106
    “…Among GLP-1 RAs, GLP-1 analogues showed a positive impact on cardiovascular and renal outcomes, while exendin-4 analogues did not.…”
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    Cardiovascular and renal outcomes with SGLT-2 inhibitors versus GLP-1 receptor agonists in patients with type 2 diabetes mellitus and chronic kidney disease: a systematic review and network meta-analysis
  7. 1107
    “…Likewise, the pursuit of gastrin and exendin antagonist-based radioligands is advancing with exciting new outcomes on the horizon. …”
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    Peptide Radioligands in Cancer Theranostics: Agonists and Antagonists
  8. 1108
    “…Exenatide (also known as exendin-4) is a glucagon-like peptide-1 mimetic, which is indicated for the treatment of type 2 diabetes mellitus. …”
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    Critical appraisal of once-weekly formulation of exenatide in the control of type 2 diabetes mellitus
  9. 1109
    “…We developed a fluorescent exendin-4-like neopeptide conjugate for the rapid purification and isolation of functional mouse pancreatic β-cells. …”
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    Rapid, high efficiency isolation of pancreatic ß-cells
  10. 1110
    por Scott, R., Minnion, J., Tan, T., Bloom, S.R.
    Publicado 2018
    “…Blockade of the GLP-1 receptor with Exendin 9–39 does not block the increase in oxygen consumption caused by OX-SR. …”
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    Oxyntomodulin analogue increases energy expenditure via the glucagon receptor
  11. 1111
    “…Here, we show that GLP-1 is a major driver of insulin secretion after bariatric surgery, as demonstrated by blocking GLP-1 receptors (GLP1Rs) post-gastrectomy in lean humans using Exendin-9 or in mice using an anti-GLP1R antibody. …”
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    Important Role of the GLP-1 Axis for Glucose Homeostasis after Bariatric Surgery
  12. 1112
    “…Using Fourier transform infrared spectroscopy measurements in the mid-infrared, we were able to characterize the interactions between a model polypeptide, exendin-4, and the PLGA copolymer. We observe a relationship between the experimentally determined [Formula: see text] and [Formula: see text] and free volume and microsphere dynamics.…”
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    Terahertz Spectroscopy: An Investigation of the Structural Dynamics of Freeze-Dried Poly Lactic-co-glycolic Acid Microspheres
  13. 1113
    “…Targeting GLP-1R with indium-111, technetium-99m or gallium-68-labeled exendin-4 offers a new approach that permits the successful localization of small benign insulinomas. …”
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    Innovative imaging of insulinoma: the end of sampling? A review
  14. 1114
    “…Studies which assess the role of gut hormones after bariatric surgery on food intake, hunger, satiety and glucose homeostasis through octreotide use (a non-specific inhibitor of gut hormone secretion) as well as with exendin 9–39 (a specific glucagon-like peptide-1 receptor antagonist) are reviewed. …”
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    Do Gut Hormones Contribute to Weight Loss and Glycaemic Outcomes after Bariatric Surgery?
  15. 1115
    “…Furthermore, the PYY receptor antagonist JNJ-31020028, GLP-1 receptor antagonist Exendin(9-39), CCK receptor antagonist Proglumide, GIP receptor antagonist GIP(3-30)NH(2) attenuated both intestinal hormone and DON-induced anorectic responses. …”
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    Deoxynivalenol (Vomitoxin)-Induced Anorexia Is Induced by the Release of Intestinal Hormones in Mice
  16. 1116
    “…This review highlights advancements in venom-derived compounds for the treatment of diabetes and related disorders. Exendin-4, originating from the saliva of Gila monster lizard, represents proof-of-concept for this drug discovery pathway in diabetes. …”
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    Therapeutic Potential of Peptides Derived from Animal Venoms: Current Views and Emerging Drugs for Diabetes
  17. 1117
    “…Amyloids have been prepared from two proteins, lysozyme and β-lactoglobulin, as well as an Exendin-4 derivative miniprotein (E5). Thermal treatment was applied to form amyloids and their structure was verified by thioflavin T (ThT), 8-Anilino-1-naphthalenesulfonic acid (ANS) dye tests and electronic circular dichroism spectroscopy (ECD). …”
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    Comparative Study of the Solid-Liquid Interfacial Adsorption of Proteins in Their Native and Amyloid Forms
  18. 1118
    por Weech, A. A., Michaelis, L.
    Publicado 1928
    “…By using the figures of Fricke and McClendon for the thickness of the membrane of the red blood cell some comparisons were drawn between the dried collodion membrane as a model for certain biological membranes and the red blood cell membrane. …”
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    STUDIES ON PERMEABILITY OF MEMBRANES : VI. MENSURATION OF THE DRIED COLLODION MEMBRANE (CALCULATION OF DIMENSIONS AND OF RELATIONS TO CERTAIN BIOLOGICAL MEMBRANES).
  19. 1119
    “…Targeting GLP-1R with the stable GLP-1 analogs (111)In-DOTA/DPTA-exendin-4 offers a new approach to successfully localize these small tumors. …”
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    Glucagon-like peptide-1 receptor overexpression in cancer and its impact on clinical applications
  20. 1120
    “…Here, we show that the GLP-1 receptor agonist exendin-4 (Ex-4) promoted bone formation and increased bone mass and quality in a rat unloading-induced bone loss model. …”
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    Activation of GLP-1 Receptor Promotes Bone Marrow Stromal Cell Osteogenic Differentiation through β-Catenin
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