Molecular basis for differential activation of p101 and p84 complexes of PI3Kγ by Ras and GPCRs

por Rathinaswamy, Manoj K., Jenkins, Meredith L., Duewell, Benjamin R., Zhang, Xuxiao, Harris, Noah J., Evans, John T., Stariha, Jordan T.B., Dalwadi, Udit, Fleming, Kaelin D., Ranga-Prasad, Harish, Yip, Calvin K., Williams, Roger L., Hansen, Scott D., Burke, John E.
Publicado 2023

Cross-reactivity of glycan-reactive HIV-1 broadly neutralizing antibodies with parasite glycans

por Huettner, Isabella, Krumm, Stefanie A., Serna, Sonia, Brzezicka, Katarzyna, Monaco, Serena, Walpole, Samuel, van Diepen, Angela, Allan, Fiona, Hicks, Thomas, Kimuda, Simon, Emery, Aidan M., Landais, Elise, Hokke, Cornelis H., Angulo, Jesus, Reichardt, Niels, Doores, Katie J.
Publicado 2022

De novo birth of functional microproteins in the human lineage

por Vakirlis, Nikolaos, Vance, Zoe, Duggan, Kate M., McLysaght, Aoife
Publicado 2022

A small RNA-guided PRC2 complex eliminates DNA as an extreme form of transposon silencing

por Wang, Chundi, Solberg, Therese, Maurer-Alcalá‬, Xyrus X., Swart, Estienne C., Gao, Feng, Nowacki, Mariusz
Publicado 2022

Large-scale all-optical dissection of motor cortex connectivity shows a segregated organization of mouse forelimb representations

por Resta, Francesco, Montagni, Elena, de Vito, Giuseppe, Scaglione, Alessandro, Allegra Mascaro, Anna Letizia, Pavone, Francesco Saverio
Publicado 2022

Spatially resolved deconvolution of the fibrotic niche in lung fibrosis

por Eyres, Michael, Bell, Joseph A., Davies, Elizabeth R., Fabre, Aurelie, Alzetani, Aiman, Jogai, Sanjay, Marshall, Ben G., Johnston, David A., Xu, Zijian, Fletcher, Sophie V., Wang, Yihua, Marshall, Gayle, Davies, Donna E., Offer, Emily, Jones, Mark G.
Publicado 2022

HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution

por Kuo, Feng-Chih, Neville, Matt J., Sabaratnam, Rugivan, Wesolowska-Andersen, Agata, Phillips, Daniel, Wittemans, Laura B.L., van Dam, Andrea D., Loh, Nellie Y., Todorčević, Marijana, Denton, Nathan, Kentistou, Katherine A., Joshi, Peter K., Christodoulides, Constantinos, Langenberg, Claudia, Collas, Philippe, Karpe, Fredrik, Pinnick, Katherine E.
Publicado 2022

Ricca’s factors as mobile proteinaceous effectors of electrical signaling

por Gao, Yong-Qiang, Jimenez-Sandoval, Pedro, Tiwari, Satyam, Stolz, Stéphanie, Wang, Jing, Glauser, Gaëtan, Santiago, Julia, Farmer, Edward E.
Publicado 2023

Ductal Ngn3-expressing progenitors contribute to adult β cell neogenesis in the pancreas

por Gribben, Christopher, Lambert, Christopher, Messal, Hendrik A., Hubber, Ella-Louise, Rackham, Chloe, Evans, Ian, Heimberg, Harry, Jones, Peter, Sancho, Rocio, Behrens, Axel
Publicado 2023

Agency affects pain inference through prior shift as opposed to likelihood precision modulation in a Bayesian pain model

por Strube, Andreas, Horing, Björn, Rose, Michael, Büchel, Christian
Publicado 2023

Light and electron microscopy continuum-resolution imaging of 3D cell cultures

por D’Imprima, Edoardo, Garcia Montero, Marta, Gawrzak, Sylwia, Ronchi, Paolo, Zagoriy, Ievgeniia, Schwab, Yannick, Jechlinger, Martin, Mahamid, Julia
Publicado 2023

Massively parallel characterization of CRISPR activator efficacy in human induced pluripotent stem cells and neurons

por Wu, Qianxin, Wu, Junjing, Karim, Kaiser, Chen, Xi, Wang, Tengyao, Iwama, Sho, Carobbio, Stefania, Keen, Peter, Vidal-Puig, Antonio, Kotter, Mark R., Bassett, Andrew
Publicado 2023

DAXX adds a de novo H3.3K9me3 deposition pathway to the histone chaperone network

por Carraro, Massimo, Hendriks, Ivo A., Hammond, Colin M., Solis-Mezarino, Victor, Völker-Albert, Moritz, Elsborg, Jonas D., Weisser, Melanie B., Spanos, Christos, Montoya, Guillermo, Rappsilber, Juri, Imhof, Axel, Nielsen, Michael L., Groth, Anja
Publicado 2023

Evaluation of T cell responses to naturally processed variant SARS-CoV-2 spike antigens in individuals following infection or vaccination

por Yin, Zixi, Chen, Ji-Li, Lu, Yongxu, Wang, Beibei, Godfrey, Leila, Mentzer, Alexander J., Yao, Xuan, Liu, Guihai, Wellington, Dannielle, Zhao, Yiqi, Wing, Peter A.C., Dejnirattisa, Wanwisa, Supasa, Piyada, Liu, Chang, Hublitz, Philip, Beveridge, Ryan, Waugh, Craig, Clark, Sally-Ann, Clark, Kevin, Sopp, Paul, Rostron, Timothy, Mongkolsapaya, Juthathip, Screaton, Gavin R., Ogg, Graham, Ewer, Katie, Pollard, Andrew J., Gilbert, Sarah, Knight, Julian C., Lambe, Teresa, Smith, Geoffrey L., Dong, Tao, Peng, Yanchun
Publicado 2023

ESCRT recruitment to SARS-CoV-2 spike induces virus-like particles that improve mRNA vaccines

por Hoffmann, Magnus A.G., Yang, Zhi, Huey-Tubman, Kathryn E., Cohen, Alexander A., Gnanapragasam, Priyanthi N.P., Nakatomi, Leesa M., Storm, Kaya N., Moon, Woohyun J., Lin, Paulo J.C., West, Anthony P., Bjorkman, Pamela J.
Publicado 2023

Sex-dependent control of pheromones on social organization within groups of wild house mice

por Zilkha, Noga, Chuartzman, Silvia Gabriela, Sofer, Yizhak, Pen, Yefim, Cum, Meghan, Mayo, Avi, Alon, Uri, Kimchi, Tali
Publicado 2023

Mechanism of signal-anchor triage during early steps of membrane protein insertion

por Wu, Haoxi, Hegde, Ramanujan S.
Publicado 2023

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes

por Baek, Kheewoong, Scott, Daniel C., Henneberg, Lukas T., King, Moeko T., Mann, Matthias, Schulman, Brenda A.
Publicado 2023

Molecular mechanisms of stress-induced reactivation in mumps virus condensates

por Zhang, Xiaojie, Sridharan, Sindhuja, Zagoriy, Ievgeniia, Eugster Oegema, Christina, Ching, Cyan, Pflaesterer, Tim, Fung, Herman K.H., Becher, Isabelle, Poser, Ina, Müller, Christoph W., Hyman, Anthony A., Savitski, Mikhail M., Mahamid, Julia
Publicado 2023

Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex

por Munz, Martin, Bharioke, Arjun, Kosche, Georg, Moreno-Juan, Verónica, Brignall, Alexandra, Rodrigues, Tiago M., Graff-Meyer, Alexandra, Ulmer, Talia, Haeuselmann, Stephanie, Pavlinic, Dinko, Ledergerber, Nicole, Gross-Scherf, Brigitte, Rózsa, Balázs, Krol, Jacek, Picelli, Simone, Cowan, Cameron S., Roska, Botond
Publicado 2023