Polarity inversion reorganizes the stem cell compartment of the trophoblast lineage

por Ozguldez, Hatice O., Govindasamy, Niraimathi, Fan, Rui, Long, Hongyan, Mildner, Karina, Zeuschner, Dagmar, Trappmann, Britta, Ranga, Adrian, Bedzhov, Ivan
Publicado 2023

c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathy

por Frezel, Noémie, Ranucci, Matteo, Foster, Edmund, Wende, Hagen, Pelczar, Pawel, Mendes, Raquel, Ganley, Robert P., Werynska, Karolina, d’Aquin, Simon, Beccarini, Camilla, Birchmeier, Carmen, Zeilhofer, Hanns Ulrich, Wildner, Hendrik
Publicado 2023

Spike rates of frontal eye field neurons predict reaction times in a spatial attention task

por Yao, Tao, Vanduffel, Wim
Publicado 2023

Astrocytes mediate cell non-autonomous correction of aberrant firing in human FXS neurons

por Sharma, Shreya Das, Reddy, Bharath Kumar, Pal, Rakhi, Ritakari, Tuula E., Cooper, James D., Selvaraj, Bhuvaneish T., Kind, Peter C., Chandran, Siddharthan, Wyllie, David J.A., Chattarji, Sumantra
Publicado 2023

Transient suppression of SUMOylation in embryonic stem cells generates embryo-like structures

por Cossec, Jack-Christophe, Traboulsi, Tatiana, Sart, Sébastien, Loe-Mie, Yann, Guthmann, Manuel, Hendriks, Ivo A., Theurillat, Ilan, Nielsen, Michael L., Torres-Padilla, Maria-Elena, Baroud, Charles N., Dejean, Anne
Publicado 2023

EndophilinA-dependent coupling between activity-induced calcium influx and synaptic autophagy is disrupted by a Parkinson-risk mutation

por Bademosi, Adekunle T., Decet, Marianna, Kuenen, Sabine, Calatayud, Carles, Swerts, Jef, Gallego, Sandra F., Schoovaerts, Nils, Karamanou, Spyridoula, Louros, Nikolaos, Martin, Ella, Sibarita, Jean-Baptiste, Vints, Katlijn, Gounko, Natalia V., Meunier, Frédéric A., Economou, Anastassios, Versées, Wim, Rousseau, Frederic, Schymkowitz, Joost, Soukup, Sandra-F., Verstreken, Patrik
Publicado 2023

PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1

por Glancy, Eleanor, Wang, Cheng, Tuck, Ellen, Healy, Evan, Amato, Simona, Neikes, Hannah K., Mariani, Andrea, Mucha, Marlena, Vermeulen, Michiel, Pasini, Diego, Bracken, Adrian P.
Publicado 2023

A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression

por Hutten, Stefan J., de Bruijn, Roebi, Lutz, Catrin, Badoux, Madelon, Eijkman, Timo, Chao, Xue, Ciwinska, Marta, Sheinman, Michael, Messal, Hendrik, Herencia-Ropero, Andrea, Kristel, Petra, Mulder, Lennart, van der Waal, Rens, Sanders, Joyce, Almekinders, Mathilde M., Llop-Guevara, Alba, Davies, Helen R., van Haren, Matthijs J., Martin, Nathaniel I., Behbod, Fariba, Nik-Zainal, Serena, Serra, Violeta, van Rheenen, Jacco, Lips, Esther H., Wessels, Lodewyk F.A., Wesseling, Jelle, Scheele, Colinda L.G.J., Jonkers, Jos
Publicado 2023

Reconstitution of Microtubule Nucleation In Vitro Reveals Novel Roles for Mzt1

por Leong, Su Ling, Lynch, Eric M., Zou, Juan, Tay, Ye Dee, Borek, Weronika E., Tuijtel, Maarten W., Rappsilber, Juri, Sawin, Kenneth E.
Publicado 2023

Nutrient-sensing AgRP neurons relay control of liver autophagy during energy deprivation

por Chen, Weiyi, Mehlkop, Oliver, Scharn, Alexandra, Nolte, Hendrik, Klemm, Paul, Henschke, Sinika, Steuernagel, Lukas, Sotelo-Hitschfeld, Tamara, Kaya, Ecem, Wunderlich, Claudia Maria, Langer, Thomas, Kononenko, Natalia L., Giavalisco, Patrick, Brüning, Jens Claus
Publicado 2023

Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome

por Healy, Michael D., McNally, Kerrie E., Butkovič, Rebeka, Chilton, Molly, Kato, Kohji, Sacharz, Joanna, McConville, Calum, Moody, Edmund R.R., Shaw, Shrestha, Planelles-Herrero, Vicente J., Yadav, Sathish K.N., Ross, Jennifer, Borucu, Ufuk, Palmer, Catherine S., Chen, Kai-En, Croll, Tristan I., Hall, Ryan J., Caruana, Nikeisha J., Ghai, Rajesh, Nguyen, Thi H.D., Heesom, Kate J., Saitoh, Shinji, Berger, Imre, Schaffitzel, Christiane, Williams, Tom A., Stroud, David A., Derivery, Emmanuel, Collins, Brett M., Cullen, Peter J.
Publicado 2023

Bilirubin gates the TRPM2 channel as a direct agonist to exacerbate ischemic brain damage

por Liu, Han-Wei, Gong, Li-Na, Lai, Ke, Yu, Xia-Fei, Liu, Zhen-Qi, Li, Ming-Xian, Yin, Xin-Lu, Liang, Min, Shi, Hao-Song, Jiang, Lin-Hua, Yang, Wei, Shi, Hai-Bo, Wang, Lu-Yang, Yin, Shan-Kai
Publicado 2023

Neuronal identity defines α-synuclein and tau toxicity

por Praschberger, Roman, Kuenen, Sabine, Schoovaerts, Nils, Kaempf, Natalie, Singh, Jeevanjot, Janssens, Jasper, Swerts, Jef, Nachman, Eliana, Calatayud, Carles, Aerts, Stein, Poovathingal, Suresh, Verstreken, Patrik
Publicado 2023

Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome

por Deni, Ioanna, Stokes, Barbara H., Ward, Kurt E., Fairhurst, Kate J., Pasaje, Charisse Flerida A., Yeo, Tomas, Akbar, Shirin, Park, Heekuk, Muir, Ryan, Bick, Daniella S., Zhan, Wenhu, Zhang, Hao, Liu, Yi Jing, Ng, Caroline L., Kirkman, Laura A., Almaliti, Jehad, Gould, Alexandra E., Duffey, Maëlle, O'Donoghue, Anthony J., Uhlemann, Anne-Catrin, Niles, Jacquin C., da Fonseca, Paula C.A., Gerwick, William H., Lin, Gang, Bogyo, Matthew, Fidock, David A.
Publicado 2023

Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling

por Longarini, Edoardo José, Dauben, Helen, Locatelli, Carolina, Wondisford, Anne R., Smith, Rebecca, Muench, Charlotte, Kolvenbach, Andreas, Lynskey, Michelle Lee, Pope, Alexis, Bonfiglio, Juan José, Jurado, Eva Pinto, Fajka-Boja, Roberta, Colby, Thomas, Schuller, Marion, Ahel, Ivan, Timinszky, Gyula, O’Sullivan, Roderick J., Huet, Sébastien, Matic, Ivan
Publicado 2023

DNA supercoiling restricts the transcriptional bursting of neighboring eukaryotic genes

por Patel, Heta P., Coppola, Stefano, Pomp, Wim, Aiello, Umberto, Brouwer, Ineke, Libri, Domenico, Lenstra, Tineke L.
Publicado 2023

A global genetic interaction network by single-cell imaging and machine learning

por Heigwer, Florian, Scheeder, Christian, Bageritz, Josephine, Yousefian, Schayan, Rauscher, Benedikt, Laufer, Christina, Beneyto-Calabuig, Sergi, Funk, Maja Christina, Peters, Vera, Boulougouri, Maria, Bilanovic, Jana, Miersch, Thilo, Schmitt, Barbara, Blass, Claudia, Port, Fillip, Boutros, Michael
Publicado 2023

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes

por Baek, Kheewoong, Scott, Daniel C., Henneberg, Lukas T., King, Moeko T., Mann, Matthias, Schulman, Brenda A.
Publicado 2023

Sites of transcription initiation drive mRNA isoform selection

por Alfonso-Gonzalez, Carlos, Legnini, Ivano, Holec, Sarah, Arrigoni, Laura, Ozbulut, Hasan Can, Mateos, Fernando, Koppstein, David, Rybak-Wolf, Agnieszka, Bönisch, Ulrike, Rajewsky, Nikolaus, Hilgers, Valérie
Publicado 2023

Pluripotent, germ cell competent adult stem cells underlie cnidarian regenerative ability and clonal growth

por Varley, Áine, Horkan, Helen R., McMahon, Emma T., Krasovec, Gabriel, Frank, Uri
Publicado 2023