Pathogenic VCP Mutations Induce Mitochondrial Uncoupling and Reduced ATP Levels

por Bartolome, Fernando, Wu, Hsiu-Chuan, Burchell, Victoria S., Preza, Elisavet, Wray, Selina, Mahoney, Colin J., Fox, Nick C., Calvo, Andrea, Canosa, Antonio, Moglia, Cristina, Mandrioli, Jessica, Chiò, Adriano, Orrell, Richard W., Houlden, Henry, Hardy, John, Abramov, Andrey Y., Plun-Favreau, Helene
Publicado 2013

Esrrb Is a Pivotal Target of the Gsk3/Tcf3 Axis Regulating Embryonic Stem Cell Self-Renewal

por Martello, Graziano, Sugimoto, Toshimi, Diamanti, Evangelia, Joshi, Anagha, Hannah, Rebecca, Ohtsuka, Satoshi, Göttgens, Berthold, Niwa, Hitoshi, Smith, Austin
Publicado 2013

An Agent Independent Axis for Executed and Modeled Choice in Medial Prefrontal Cortex

por Nicolle, Antoinette, Klein-Flügge, Miriam C., Hunt, Laurence T., Vlaev, Ivo, Dolan, Raymond J., Behrens, Timothy E.J.
Publicado 2013

Role of K(ATP) Channels in Glucose-Regulated Glucagon Secretion and Impaired Counterregulation in Type 2 Diabetes

por Zhang, Quan, Ramracheya, Reshma, Lahmann, Carolina, Tarasov, Andrei, Bengtsson, Martin, Braha, Orit, Braun, Matthias, Brereton, Melissa, Collins, Stephan, Galvanovskis, Juris, Gonzalez, Alejandro, Groschner, Lukas N., Rorsman, Nils J.G., Salehi, Albert, Travers, Mary E., Walker, Jonathan N., Gloyn, Anna L., Gribble, Fiona, Johnson, Paul R.V., Reimann, Frank, Ashcroft, Frances M., Rorsman, Patrik
Publicado 2013

Evolutionary Adaptation of the Fly Pygo PHD Finger toward Recognizing Histone H3 Tail Methylated at Arginine 2

por Miller, Thomas C.R., Mieszczanek, Juliusz, Sánchez-Barrena, María José, Rutherford, Trevor J., Fiedler, Marc, Bienz, Mariann
Publicado 2013

The Structure of the RLIP76 RhoGAP-Ral Binding Domain Dyad: Fixed Position of the Domains Leads to Dual Engagement of Small G Proteins at the Membrane

por Rajasekar, Karthik V., Campbell, Louise J., Nietlispach, Daniel, Owen, Darerca, Mott, Helen R.
Publicado 2013

Transplantation of Expanded Fetal Intestinal Progenitors Contributes to Colon Regeneration after Injury

por Fordham, Robert P., Yui, Shiro, Hannan, Nicholas R.F., Soendergaard, Christoffer, Madgwick, Alison, Schweiger, Pawel J., Nielsen, Ole H., Vallier, Ludovic, Pedersen, Roger A., Nakamura, Tetsuya, Watanabe, Mamoru, Jensen, Kim B.
Publicado 2013

Intracellular Complement Activation Sustains T Cell Homeostasis and Mediates Effector Differentiation

por Liszewski, M. Kathryn, Kolev, Martin, Le Friec, Gaelle, Leung, Marilyn, Bertram, Paula G., Fara, Antonella F., Subias, Marta, Pickering, Matthew C., Drouet, Christian, Meri, Seppo, Arstila, T. Petteri, Pekkarinen, Pirkka T., Ma, Margaret, Cope, Andrew, Reinheckel, Thomas, Rodriguez de Cordoba, Santiago, Afzali, Behdad, Atkinson, John P., Kemper, Claudia
Publicado 2013

The Behavioral and Neural Mechanisms Underlying the Tracking of Expertise

por Boorman, Erie D., O’Doherty, John P., Adolphs, Ralph, Rangel, Antonio
Publicado 2013

Variable Dendritic Integration in Hippocampal CA3 Pyramidal Neurons

por Makara, Judit K., Magee, Jeffrey C.
Publicado 2013

Dynamic Analysis of Gene Expression and Genome-wide Transcription Factor Binding during Lineage Specification of Multipotent Progenitors

por May, Gillian, Soneji, Shamit, Tipping, Alex J., Teles, Jose, McGowan, Simon J., Wu, Mengchu, Guo, Yanping, Fugazza, Cristina, Brown, John, Karlsson, Göran, Pina, Cristina, Olariu, Victor, Taylor, Stephen, Tenen, Daniel G., Peterson, Carsten, Enver, Tariq
Publicado 2013

Structural Interactions between Inhibitor and Substrate Docking Sites Give Insight into Mechanisms of Human PS1 Complexes

por Li, Yi, Lu, Stephen Hsueh-Jeng, Tsai, Ching-Ju, Bohm, Christopher, Qamar, Seema, Dodd, Roger B., Meadows, William, Jeon, Amy, McLeod, Adam, Chen, Fusheng, Arimon, Muriel, Berezovska, Oksana, Hyman, Bradley T., Tomita, Taisuke, Iwatsubo, Takeshi, Johnson, Christopher M., Farrer, Lindsay A., Schmitt-Ulms, Gerold, Fraser, Paul E., St George-Hyslop, Peter H.
Publicado 2014

Analysis of Transcription Factors Key for Mouse Pancreatic Development Establishes NKX2-2 and MNX1 Mutations as Causes of Neonatal Diabetes in Man

por Flanagan, Sarah E., De Franco, Elisa, Lango Allen, Hana, Zerah, Michele, Abdul-Rasoul, Majedah M., Edge, Julie A., Stewart, Helen, Alamiri, Elham, Hussain, Khalid, Wallis, Sam, de Vries, Liat, Rubio-Cabezas, Oscar, Houghton, Jayne A.L., Edghill, Emma L., Patch, Ann-Marie, Ellard, Sian, Hattersley, Andrew T.
Publicado 2014

Structure and Self-Assembly of the Calcium Binding Matrix Protein of Human Metapneumovirus

por Leyrat, Cedric, Renner, Max, Harlos, Karl, Huiskonen, Juha T., Grimes, Jonathan M.
Publicado 2014

Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands

por Chillakuri, Chandramouli R., Sheppard, Devon, Ilagan, Ma. Xenia G., Holt, Laurie R., Abbott, Felicity, Liang, Shaoyan, Kopan, Raphael, Handford, Penny A., Lea, Susan M.
Publicado 2013

Disruption of Dorsolateral Prefrontal Cortex Decreases Model-Based in Favor of Model-free Control in Humans

por Smittenaar, Peter, FitzGerald, Thomas H.B., Romei, Vincenzo, Wright, Nicholas D., Dolan, Raymond J.
Publicado 2013

A Single Subset of Dendritic Cells Controls the Cytokine Bias of Natural Killer T Cell Responses to Diverse Glycolipid Antigens

por Arora, Pooja, Baena, Andres, Yu, Karl O.A., Saini, Neeraj K., Kharkwal, Shalu S., Goldberg, Michael F., Kunnath-Velayudhan, Shajo, Carreño, Leandro J., Venkataswamy, Manjunatha M., Kim, John, Lazar-Molnar, Eszter, Lauvau, Gregoire, Chang, Young-tae, Liu, Zheng, Bittman, Robert, Al-Shamkhani, Aymen, Cox, Liam R., Jervis, Peter J., Veerapen, Natacha, Besra, Gurdyal S., Porcelli, Steven A.
Publicado 2014

Tip Cells Act as Dynamic Cellular Anchors in the Morphogenesis of Looped Renal Tubules in Drosophila

por Weavers, Helen, Skaer, Helen
Publicado 2013

Genome-wide Mapping of Transcriptional Start Sites Defines an Extensive Leaderless Transcriptome in Mycobacterium tuberculosis

por Cortes, Teresa, Schubert, Olga T., Rose, Graham, Arnvig, Kristine B., Comas, Iñaki, Aebersold, Ruedi, Young, Douglas B.
Publicado 2013

The GPS Motif Is a Molecular Switch for Bimodal Activities of Adhesion Class G Protein-Coupled Receptors

por Prömel, Simone, Frickenhaus, Marie, Hughes, Samantha, Mestek, Lamia, Staunton, David, Woollard, Alison, Vakonakis, Ioannis, Schöneberg, Torsten, Schnabel, Ralf, Russ, Andreas P., Langenhan, Tobias
Publicado 2012