Molecular Basis of Histone Tail Recognition by Human TIP5 PHD Finger and Bromodomain of the Chromatin Remodeling Complex NoRC

por Tallant, Cynthia, Valentini, Erica, Fedorov, Oleg, Overvoorde, Lois, Ferguson, Fleur M., Filippakopoulos, Panagis, Svergun, Dmitri I., Knapp, Stefan, Ciulli, Alessio
Publicado 2015

The Endothelial Transcription Factor ERG Promotes Vascular Stability and Growth through Wnt/β-Catenin Signaling

por Birdsey, Graeme M., Shah, Aarti V., Dufton, Neil, Reynolds, Louise E., Osuna Almagro, Lourdes, Yang, Youwen, Aspalter, Irene M., Khan, Samia T., Mason, Justin C., Dejana, Elisabetta, Göttgens, Berthold, Hodivala-Dilke, Kairbaan, Gerhardt, Holger, Adams, Ralf H., Randi, Anna M.
Publicado 2015

Conformation of the Human Immunoglobulin G2 Hinge Imparts Superagonistic Properties to Immunostimulatory Anticancer Antibodies

por White, Ann L., Chan, H.T. Claude, French, Ruth R., Willoughby, Jane, Mockridge, C. Ian, Roghanian, Ali, Penfold, Christine A., Booth, Steven G., Dodhy, Ali, Polak, Marta E., Potter, Elizabeth A., Ardern-Jones, Michael R., Verbeek, J. Sjef, Johnson, Peter W.M., Al-Shamkhani, Aymen, Cragg, Mark S., Beers, Stephen A., Glennie, Martin J.
Publicado 2015

Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress

por Schug, Zachary T., Peck, Barrie, Jones, Dylan T., Zhang, Qifeng, Grosskurth, Shaun, Alam, Israt S., Goodwin, Louise M., Smethurst, Elizabeth, Mason, Susan, Blyth, Karen, McGarry, Lynn, James, Daniel, Shanks, Emma, Kalna, Gabriela, Saunders, Rebecca E., Jiang, Ming, Howell, Michael, Lassailly, Francois, Thin, May Zaw, Spencer-Dene, Bradley, Stamp, Gordon, van den Broek, Niels J.F., Mackay, Gillian, Bulusu, Vinay, Kamphorst, Jurre J., Tardito, Saverio, Strachan, David, Harris, Adrian L., Aboagye, Eric O., Critchlow, Susan E., Wakelam, Michael J.O., Schulze, Almut, Gottlieb, Eyal
Publicado 2015

Paradox-Breaking RAF Inhibitors that Also Target SRC Are Effective in Drug-Resistant BRAF Mutant Melanoma

por Girotti, Maria Romina, Lopes, Filipa, Preece, Natasha, Niculescu-Duvaz, Dan, Zambon, Alfonso, Davies, Lawrence, Whittaker, Steven, Saturno, Grazia, Viros, Amaya, Pedersen, Malin, Suijkerbuijk, Bart M.J.M., Menard, Delphine, McLeary, Robert, Johnson, Louise, Fish, Laura, Ejiama, Sarah, Sanchez-Laorden, Berta, Hohloch, Juliane, Carragher, Neil, Macleod, Kenneth, Ashton, Garry, Marusiak, Anna A., Fusi, Alberto, Brognard, John, Frame, Margaret, Lorigan, Paul, Marais, Richard, Springer, Caroline
Publicado 2015

Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease

por Hill, Rebecca M., Kuijper, Sanne, Lindsey, Janet C., Petrie, Kevin, Schwalbe, Ed C., Barker, Karen, Boult, Jessica K.R., Williamson, Daniel, Ahmad, Zai, Hallsworth, Albert, Ryan, Sarra L., Poon, Evon, Robinson, Simon P., Ruddle, Ruth, Raynaud, Florence I., Howell, Louise, Kwok, Colin, Joshi, Abhijit, Nicholson, Sarah Leigh, Crosier, Stephen, Ellison, David W., Wharton, Stephen B., Robson, Keith, Michalski, Antony, Hargrave, Darren, Jacques, Thomas S., Pizer, Barry, Bailey, Simon, Swartling, Fredrik J., Weiss, William A., Chesler, Louis, Clifford, Steven C.
Publicado 2015

A PfRH5-Based Vaccine Is Efficacious against Heterologous Strain Blood-Stage Plasmodium falciparum Infection in Aotus Monkeys

por Douglas, Alexander D., Baldeviano, G. Christian, Lucas, Carmen M., Lugo-Roman, Luis A., Crosnier, Cécile, Bartholdson, S. Josefin, Diouf, Ababacar, Miura, Kazutoyo, Lambert, Lynn E., Ventocilla, Julio A., Leiva, Karina P., Milne, Kathryn H., Illingworth, Joseph J., Spencer, Alexandra J., Hjerrild, Kathryn A., Alanine, Daniel G.W., Turner, Alison V., Moorhead, Jeromy T., Edgel, Kimberly A., Wu, Yimin, Long, Carole A., Wright, Gavin J., Lescano, Andrés G., Draper, Simon J.
Publicado 2015

Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria

por Lau, Clinton K.Y., Turner, Louise, Jespersen, Jakob S., Lowe, Edward D., Petersen, Bent, Wang, Christian W., Petersen, Jens E.V., Lusingu, John, Theander, Thor G., Lavstsen, Thomas, Higgins, Matthew K.
Publicado 2015

Individual Differences in Alpha Frequency Drive Crossmodal Illusory Perception

por Cecere, Roberto, Rees, Geraint, Romei, Vincenzo
Publicado 2015

Macrophage-Derived upd3 Cytokine Causes Impaired Glucose Homeostasis and Reduced Lifespan in Drosophila Fed a Lipid-Rich Diet

por Woodcock, Katie J., Kierdorf, Katrin, Pouchelon, Clara A., Vivancos, Valérie, Dionne, Marc S., Geissmann, Frédéric
Publicado 2015

In Vivo Measurement of Cell-Type-Specific Synaptic Connectivity and Synaptic Transmission in Layer 2/3 Mouse Barrel Cortex

por Pala, Aurélie, Petersen, Carl C.H.
Publicado 2015

Protein Arginine Methyltransferase 6 Enhances Polyglutamine-Expanded Androgen Receptor Function and Toxicity in Spinal and Bulbar Muscular Atrophy

por Scaramuzzino, Chiara, Casci, Ian, Parodi, Sara, Lievens, Patricia M.J., Polanco, Maria J., Milioto, Carmelo, Chivet, Mathilde, Monaghan, John, Mishra, Ashutosh, Badders, Nisha, Aggarwal, Tanya, Grunseich, Christopher, Sambataro, Fabio, Basso, Manuela, Fackelmayer, Frank O., Taylor, J. Paul, Pandey, Udai Bhan, Pennuto, Maria
Publicado 2015

Diet-Induced Unresolved ER Stress Hinders KRAS-Driven Lung Tumorigenesis

por Ramadori, Giorgio, Konstantinidou, Georgia, Venkateswaran, Niranjan, Biscotti, Tommasina, Morlock, Lorraine, Galié, Mirco, Williams, Noelle S., Luchetti, Michele, Santinelli, Alfredo, Scaglioni, Pier Paolo, Coppari, Roberto
Publicado 2015

Nanoscale Distribution of Presynaptic Ca(2+) Channels and Its Impact on Vesicular Release during Development

por Nakamura, Yukihiro, Harada, Harumi, Kamasawa, Naomi, Matsui, Ko, Rothman, Jason S., Shigemoto, Ryuichi, Silver, R. Angus, DiGregorio, David A., Takahashi, Tomoyuki
Publicado 2015

Molecular Basis for SMC Rod Formation and Its Dissolution upon DNA Binding

por Soh, Young-Min, Bürmann, Frank, Shin, Ho-Chul, Oda, Takashi, Jin, Kyeong Sik, Toseland, Christopher P., Kim, Cheolhee, Lee, Hansol, Kim, Soo Jin, Kong, Min-Seok, Durand-Diebold, Marie-Laure, Kim, Yeon-Gil, Kim, Ho Min, Lee, Nam Ki, Sato, Mamoru, Oh, Byung-Ha, Gruber, Stephan
Publicado 2015

PI(5)P Regulates Autophagosome Biogenesis

por Vicinanza, Mariella, Korolchuk, Viktor I., Ashkenazi, Avraham, Puri, Claudia, Menzies, Fiona M., Clarke, Jonathan H., Rubinsztein, David C.
Publicado 2015

Microbiota Controls the Homeostasis of Glial Cells in the Gut Lamina Propria

por Kabouridis, Panagiotis S., Lasrado, Reena, McCallum, Sarah, Chng, Song Hui, Snippert, Hugo J., Clevers, Hans, Pettersson, Sven, Pachnis, Vassilis
Publicado 2015

Learning-Induced Plasticity in Medial Prefrontal Cortex Predicts Preference Malleability

por Garvert, Mona M., Moutoussis, Michael, Kurth-Nelson, Zeb, Behrens, Timothy E.J., Dolan, Raymond J.
Publicado 2015

Cholinergic Afferent Stimulation Induces Axonal Function Plasticity in Adult Hippocampal Granule Cells

por Martinello, Katiuscia, Huang, Zhuo, Lujan, Rafael, Tran, Baouyen, Watanabe, Masahiko, Cooper, Edward C., Brown, David A., Shah, Mala M.
Publicado 2015

Bacterial Metabolite Indole Modulates Incretin Secretion from Intestinal Enteroendocrine L Cells

por Chimerel, Catalin, Emery, Edward, Summers, David K., Keyser, Ulrich, Gribble, Fiona M., Reimann, Frank
Publicado 2014