MtrA modulates Mycobacterium tuberculosis cell division in host microenvironments to mediate intrinsic resistance and drug tolerance

por Peterson, Eliza J.R., Brooks, Aaron N., Reiss, David J., Kaur, Amardeep, Do, Julie, Pan, Min, Wu, Wei-Ju, Morrison, Robert, Srinivas, Vivek, Carter, Warren, Arrieta-Ortiz, Mario L., Ruiz, Rene A., Bhatt, Apoorva, Baliga, Nitin S.
Publicado 2023

Phage-assisted evolution and protein engineering yield compact, efficient prime editors

por Doman, Jordan L., Pandey, Smriti, Neugebauer, Monica E., An, Meirui, Davis, Jessie R., Randolph, Peyton B., McElroy, Amber, Gao, Xin D., Raguram, Aditya, Richter, Michelle F., Everette, Kelcee A., Banskota, Samagya, Tian, Kathryn, Tao, Y. Allen, Tolar, Jakub, Osborn, Mark J., Liu, David R.
Publicado 2023

Neddylation of phosphoenolpyruvate carboxykinase 1 controls glucose metabolism

por Gonzalez-Rellan, María J., Fernández, Uxía, Parracho, Tamara, Novoa, Eva, Fondevila, Marcos F., da Silva Lima, Natalia, Ramos, Lucía, Rodríguez, Amaia, Serrano-Maciá, Marina, Perez-Mejias, Gonzalo, Chantada-Vazquez, Pilar, Riobello, Cristina, Veyrat-Durebex, Christelle, Tovar, Sulay, Coppari, Roberto, Woodhoo, Ashwin, Schwaninger, Markus, Prevot, Vincent, Delgado, Teresa C., Lopez, Miguel, Diaz-Quintana, Antonio, Dieguez, Carlos, Guallar, Diana, Frühbeck, Gema, Diaz-Moreno, Irene, Bravo, Susana B., Martinez-Chantar, Maria L., Nogueiras, Ruben
Publicado 2023

Genomes from a medieval mass burial show Ashkenazi-associated hereditary diseases pre-date the 12th century

por Brace, Selina, Diekmann, Yoan, Booth, Thomas, Macleod, Ruairidh, Timpson, Adrian, Stephen, Will, Emery, Giles, Cabot, Sophie, Thomas, Mark G., Barnes, Ian
Publicado 2022

Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation

por Ferreira, Ana C.F., Szeto, Aydan C.H., Clark, Paula A., Crisp, Alastair, Kozik, Patrycja, Jolin, Helen E., McKenzie, Andrew N.J.
Publicado 2023

Control of mRNA fate by its encoded nascent polypeptide

por Höpfler, Markus, Hegde, Ramanujan S.
Publicado 2023

How Pol α-primase is targeted to replisomes to prime eukaryotic DNA replication

por Jones, Morgan L., Aria, Valentina, Baris, Yasemin, Yeeles, Joseph T.P.
Publicado 2023

Mechanism of orphan subunit recognition during assembly quality control

por Yagita, Yuichi, Zavodszky, Eszter, Peak-Chew, Sew-Yeu, Hegde, Ramanujan S.
Publicado 2023

Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study

por Wagner, Sophia J., Reisenbüchler, Daniel, West, Nicholas P., Niehues, Jan Moritz, Zhu, Jiefu, Foersch, Sebastian, Veldhuizen, Gregory Patrick, Quirke, Philip, Grabsch, Heike I., van den Brandt, Piet A., Hutchins, Gordon G.A., Richman, Susan D., Yuan, Tanwei, Langer, Rupert, Jenniskens, Josien C.A., Offermans, Kelly, Mueller, Wolfram, Gray, Richard, Gruber, Stephen B., Greenson, Joel K., Rennert, Gad, Bonner, Joseph D., Schmolze, Daniel, Jonnagaddala, Jitendra, Hawkins, Nicholas J., Ward, Robyn L., Morton, Dion, Seymour, Matthew, Magill, Laura, Nowak, Marta, Hay, Jennifer, Koelzer, Viktor H., Church, David N., Matek, Christian, Geppert, Carol, Peng, Chaolong, Zhi, Cheng, Ouyang, Xiaoming, James, Jacqueline A., Loughrey, Maurice B., Salto-Tellez, Manuel, Brenner, Hermann, Hoffmeister, Michael, Truhn, Daniel, Schnabel, Julia A., Boxberg, Melanie, Peng, Tingying, Kather, Jakob Nikolas
Publicado 2023

Machine learning identifies experimental brain metastasis subtypes based on their influence on neural circuits

por Sanchez-Aguilera, Alberto, Masmudi-Martín, Mariam, Navas-Olive, Andrea, Baena, Patricia, Hernández-Oliver, Carolina, Priego, Neibla, Cordón-Barris, Lluís, Alvaro-Espinosa, Laura, García, Santiago, Martínez, Sonia, Lafarga, Miguel, Lin, Michael Z, Al-Shahrour, Fátima, Menendez de la Prida, Liset, Valiente, Manuel
Publicado 2023

Customization of the translational complex regulates mRNA-specific translation to control CNS regeneration

por Schaeffer, Julia, Vilallongue, Noemie, Decourt, Charlotte, Blot, Beatrice, El Bakdouri, Nacera, Plissonnier, Elise, Excoffier, Blandine, Paccard, Antoine, Diaz, Jean-Jacques, Humbert, Sandrine, Catez, Frederic, Saudou, Frederic, Nawabi, Homaira, Belin, Stephane
Publicado 2023

Engram stability and maturation during systems consolidation

por Refaeli, Ron, Kreisel, Tirzah, Groysman, Maya, Adamsky, Adar, Goshen, Inbal
Publicado 2023

Dimensionality reduction reveals separate translation and rotation populations in the zebrafish hindbrain

por Feierstein, Claudia E., de Goeij, Michelle H.M., Ostrovsky, Aaron D., Laborde, Alexandre, Portugues, Ruben, Orger, Michael B., Machens, Christian K.
Publicado 2023

An ancient pan-cnidarian microRNA regulates stinging capsule biogenesis in Nematostella vectensis

por Fridrich, Arie, Salinas-Saaverda, Miguel, Kozlolvski, Itamar, Surm, Joachim M., Chrysostomou, Eleni, Tripathi, Abhinandan M., Frank, Uri, Moran, Yehu
Publicado 2023

Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson’s disease

por Schmit, Kristopher J., Garcia, Pierre, Sciortino, Alessia, Aho, Velma T.E., Pardo Rodriguez, Beatriz, Thomas, Mélanie H., Gérardy, Jean-Jacques, Bastero Acha, Irati, Halder, Rashi, Cialini, Camille, Heurtaux, Tony, Ostahi, Irina, Busi, Susheel B., Grandmougin, Léa, Lowndes, Tuesday, Singh, Yogesh, Martens, Eric C., Mittelbronn, Michel, Buttini, Manuel, Wilmes, Paul
Publicado 2023

Intra- and interchromosomal contact mapping reveals the Igh locus has extensive conformational heterogeneity and interacts with B-lineage genes

por Mielczarek, Olga, Rogers, Carolyn H., Zhan, Yinxiu, Matheson, Louise S., Stubbington, Michael J.T., Schoenfelder, Stefan, Bolland, Daniel J., Javierre, Biola M., Wingett, Steven W., Várnai, Csilla, Segonds-Pichon, Anne, Conn, Simon J., Krueger, Felix, Andrews, Simon, Fraser, Peter, Giorgetti, Luca, Corcoran, Anne E.
Publicado 2023

Anillin forms linear structures and facilitates furrow ingression after septin and formin depletion

por Lebedev, Mikhail, Chan, Fung-Yi, Lochner, Anna, Bellessem, Jennifer, Osório, Daniel S., Rackles, Elisabeth, Mikeladze-Dvali, Tamara, Carvalho, Ana Xavier, Zanin, Esther
Publicado 2023

Play and tickling responses map to the lateral columns of the rat periaqueductal gray

por Gloveli, Natalie, Simonnet, Jean, Tang, Wei, Concha-Miranda, Miguel, Maier, Eduard, Dvorzhak, Anton, Schmitz, Dietmar, Brecht, Michael
Publicado 2023

S-acylation of p62 promotes p62 droplet recruitment into autophagosomes in mammalian autophagy

por Huang, Xue, Yao, Jia, Liu, Lu, Chen, Jing, Mei, Ligang, Huangfu, Jingjing, Luo, Dong, Wang, Xinyi, Lin, Changhai, Chen, Xiaorong, Yang, Yi, Ouyang, Sheng, Wei, Fujing, Wang, Zhuolin, Zhang, Shaolin, Xiang, Tingxiu, Neculai, Dante, Sun, Qiming, Kong, Eryan, Tate, Edward W., Yang, Aimin
Publicado 2023

Regulatory T cells require IL6 receptor alpha signaling to control skeletal muscle function and regeneration

por Becker, Maike, Joseph, Sini S., Garcia-Carrizo, Francisco, Tom, Robby Z., Opaleva, Daria, Serr, Isabelle, Tschöp, Matthias H., Schulz, Tim J., Hofmann, Susanna M., Daniel, Carolin
Publicado 2023