Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex

por Llácer, Jose L., Hussain, Tanweer, Marler, Laura, Aitken, Colin Echeverría, Thakur, Anil, Lorsch, Jon R., Hinnebusch, Alan G., Ramakrishnan, V.
Publicado 2015

GIT1 and βPIX Are Essential for GABA(A) Receptor Synaptic Stability and Inhibitory Neurotransmission

por Smith, Katharine R., Davenport, Elizabeth C., Wei, Jing, Li, Xiangning, Pathania, Manavendra, Vaccaro, Victoria, Yan, Zhen, Kittler, Josef T.
Publicado 2014

Rewiring of an Epithelial Differentiation Factor, miR-203, to Inhibit Human Squamous Cell Carcinoma Metastasis

por Benaich, Nathan, Woodhouse, Samuel, Goldie, Stephen J., Mishra, Ajay, Quist, Sven R., Watt, Fiona M.
Publicado 2014

A Targeted Oligonucleotide Enhancer of SMN2 Exon 7 Splicing Forms Competing Quadruplex and Protein Complexes in Functional Conditions

por Smith, Lindsay D., Dickinson, Rachel L., Lucas, Christian M., Cousins, Alex, Malygin, Alexey A., Weldon, Carika, Perrett, Andrew J., Bottrill, Andrew R., Searle, Mark S., Burley, Glenn A., Eperon, Ian C.
Publicado 2014

Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion

por Gheni, Ghupurjan, Ogura, Masahito, Iwasaki, Masahiro, Yokoi, Norihide, Minami, Kohtaro, Nakayama, Yasumune, Harada, Kazuo, Hastoy, Benoit, Wu, Xichen, Takahashi, Harumi, Kimura, Kazushi, Matsubara, Toshiya, Hoshikawa, Ritsuko, Hatano, Naoya, Sugawara, Kenji, Shibasaki, Tadao, Inagaki, Nobuya, Bamba, Takeshi, Mizoguchi, Akira, Fukusaki, Eiichiro, Rorsman, Patrik, Seino, Susumu
Publicado 2014

Granules Harboring Translationally Active mRNAs Provide a Platform for P-Body Formation following Stress

por Lui, Jennifer, Castelli, Lydia M., Pizzinga, Mariavittoria, Simpson, Clare E., Hoyle, Nathaniel P., Bailey, Kathryn L., Campbell, Susan G., Ashe, Mark P.
Publicado 2014

Insights into the Evolution of Longevity from the Bowhead Whale Genome

por Keane, Michael, Semeiks, Jeremy, Webb, Andrew E., Li, Yang I., Quesada, Víctor, Craig, Thomas, Madsen, Lone Bruhn, van Dam, Sipko, Brawand, David, Marques, Patrícia I., Michalak, Pawel, Kang, Lin, Bhak, Jong, Yim, Hyung-Soon, Grishin, Nick V., Nielsen, Nynne Hjort, Heide-Jørgensen, Mads Peter, Oziolor, Elias M., Matson, Cole W., Church, George M., Stuart, Gary W., Patton, John C., George, J. Craig, Suydam, Robert, Larsen, Knud, López-Otín, Carlos, O’Connell, Mary J., Bickham, John W., Thomsen, Bo, de Magalhães, João Pedro
Publicado 2015

Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation

por Tremaroli, Valentina, Karlsson, Fredrik, Werling, Malin, Ståhlman, Marcus, Kovatcheva-Datchary, Petia, Olbers, Torsten, Fändriks, Lars, le Roux, Carel W., Nielsen, Jens, Bäckhed, Fredrik
Publicado 2015

Cell Competition Modifies Adult Stem Cell and Tissue Population Dynamics in a JAK-STAT-Dependent Manner

por Kolahgar, Golnar, Suijkerbuijk, Saskia J.E., Kucinski, Iwo, Poirier, Enzo Z., Mansour, Sarah, Simons, Benjamin D., Piddini, Eugenia
Publicado 2015

The Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven Axis

por Parsons, Michael J., Brancaccio, Marco, Sethi, Siddharth, Maywood, Elizabeth S., Satija, Rahul, Edwards, Jessica K., Jagannath, Aarti, Couch, Yvonne, Finelli, Mattéa J., Smyllie, Nicola J., Esapa, Christopher, Butler, Rachel, Barnard, Alun R., Chesham, Johanna E., Saito, Shoko, Joynson, Greg, Wells, Sara, Foster, Russell G., Oliver, Peter L., Simon, Michelle M., Mallon, Ann-Marie, Hastings, Michael H., Nolan, Patrick M.
Publicado 2015

Patterned Anchorage to the Apical Extracellular Matrix Defines Tissue Shape in the Developing Appendages of Drosophila

por Ray, Robert P., Matamoro-Vidal, Alexis, Ribeiro, Paulo S., Tapon, Nic, Houle, David, Salazar-Ciudad, Isaac, Thompson, Barry J.
Publicado 2015

Early-Life Stress Triggers Juvenile Zebra Finches to Switch Social Learning Strategies

por Farine, Damien R., Spencer, Karen A., Boogert, Neeltje J.
Publicado 2015

Restoration of Vision with Ectopic Expression of Human Rod Opsin

por Cehajic-Kapetanovic, Jasmina, Eleftheriou, Cyril, Allen, Annette E., Milosavljevic, Nina, Pienaar, Abigail, Bedford, Robert, Davis, Katherine E., Bishop, Paul N., Lucas, Robert J.
Publicado 2015

Cdk1 Restrains NHEJ through Phosphorylation of XRCC4-like Factor Xlf1

por Hentges, Pierre, Waller, Helen, Reis, Clara C., Ferreira, Miguel Godinho, Doherty, Aidan J.
Publicado 2014

Genome-wide RNAi Screen Reveals a Role for Multipass Membrane Proteins in Endosome-to-Golgi Retrieval

por Breusegem, Sophia Y., Seaman, Matthew N.J.
Publicado 2014

Direct Reprogramming of Murine Fibroblasts to Hematopoietic Progenitor Cells

por Batta, Kiran, Florkowska, Magdalena, Kouskoff, Valerie, Lacaud, Georges
Publicado 2014

Trim25 Is an RNA-Specific Activator of Lin28a/TuT4-Mediated Uridylation

por Choudhury, Nila Roy, Nowak, Jakub S., Zuo, Juan, Rappsilber, Juri, Spoel, Steven H., Michlewski, Gracjan
Publicado 2014

The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA

por Mannion, Niamh M., Greenwood, Sam M., Young, Robert, Cox, Sarah, Brindle, James, Read, David, Nellåker, Christoffer, Vesely, Cornelia, Ponting, Chris P., McLaughlin, Paul J., Jantsch, Michael F., Dorin, Julia, Adams, Ian R., Scadden, A.D.J., Öhman, Marie, Keegan, Liam P., O’Connell, Mary A.
Publicado 2014

Rfx6 Maintains the Functional Identity of Adult Pancreatic β Cells

por Piccand, Julie, Strasser, Perrine, Hodson, David J., Meunier, Aline, Ye, Tao, Keime, Céline, Birling, Marie-Christine, Rutter, Guy A., Gradwohl, Gérard
Publicado 2014

Genome-wide Bisulfite Sequencing in Zygotes Identifies Demethylation Targets and Maps the Contribution of TET3 Oxidation

por Peat, Julian R., Dean, Wendy, Clark, Stephen J., Krueger, Felix, Smallwood, Sébastien A., Ficz, Gabriella, Kim, Jong Kyoung, Marioni, John C., Hore, Timothy A., Reik, Wolf
Publicado 2014