Ctf4 Links DNA Replication with Sister Chromatid Cohesion Establishment by Recruiting the Chl1 Helicase to the Replisome

por Samora, Catarina P., Saksouk, Julie, Goswami, Panchali, Wade, Ben O., Singleton, Martin R., Bates, Paul A., Lengronne, Armelle, Costa, Alessandro, Uhlmann, Frank
Publicado 2016

Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase

por Villa, Fabrizio, Simon, Aline C., Ortiz Bazan, Maria Angeles, Kilkenny, Mairi L., Wirthensohn, David, Wightman, Mel, Matak-Vinkovíc, Dijana, Pellegrini, Luca, Labib, Karim
Publicado 2016

Structure of a Complete ATP Synthase Dimer Reveals the Molecular Basis of Inner Mitochondrial Membrane Morphology

por Hahn, Alexander, Parey, Kristian, Bublitz, Maike, Mills, Deryck J., Zickermann, Volker, Vonck, Janet, Kühlbrandt, Werner, Meier, Thomas
Publicado 2016

Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-β-Catenin Signaling

por Mariotti, Laura, Templeton, Catherine M., Ranes, Michael, Paracuellos, Patricia, Cronin, Nora, Beuron, Fabienne, Morris, Edward, Guettler, Sebastian
Publicado 2016

Structural Basis for Plexin Activation and Regulation

por Kong, Youxin, Janssen, Bert J.C., Malinauskas, Tomas, Vangoor, Vamshidhar R., Coles, Charlotte H., Kaufmann, Rainer, Ni, Tao, Gilbert, Robert J.C., Padilla-Parra, Sergi, Pasterkamp, R. Jeroen, Jones, E. Yvonne
Publicado 2016

PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition

por Castel, Pau, Ellis, Haley, Bago, Ruzica, Toska, Eneda, Razavi, Pedram, Carmona, F. Javier, Kannan, Srinivasaraghavan, Verma, Chandra S., Dickler, Maura, Chandarlapaty, Sarat, Brogi, Edi, Alessi, Dario R., Baselga, José, Scaltriti, Maurizio
Publicado 2016

Microtubule-Dependent Mitochondria Alignment Regulates Calcium Release in Response to Nanomechanical Stimulus in Heart Myocytes

por Miragoli, Michele, Sanchez-Alonso, Jose L., Bhargava, Anamika, Wright, Peter T., Sikkel, Markus, Schobesberger, Sophie, Diakonov, Ivan, Novak, Pavel, Castaldi, Alessandra, Cattaneo, Paola, Lyon, Alexander R., Lab, Max J., Gorelik, Julia
Publicado 2015

De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data

por Grün, Dominic, Muraro, Mauro J., Boisset, Jean-Charles, Wiebrands, Kay, Lyubimova, Anna, Dharmadhikari, Gitanjali, van den Born, Maaike, van Es, Johan, Jansen, Erik, Clevers, Hans, de Koning, Eelco J.P., van Oudenaarden, Alexander
Publicado 2016

Changing Balance of Spinal Cord Excitability and Nociceptive Brain Activity in Early Human Development

por Hartley, Caroline, Moultrie, Fiona, Gursul, Deniz, Hoskin, Amy, Adams, Eleri, Rogers, Richard, Slater, Rebeccah
Publicado 2016

Mycobacterial Acid Tolerance Enables Phagolysosomal Survival and Establishment of Tuberculous Infection In Vivo

por Levitte, Steven, Adams, Kristin N., Berg, Russell D., Cosma, Christine L., Urdahl, Kevin B., Ramakrishnan, Lalita
Publicado 2016

Automatic Segmentation of Drosophila Neural Compartments Using GAL4 Expression Data Reveals Novel Visual Pathways

por Panser, Karin, Tirian, Laszlo, Schulze, Florian, Villalba, Santiago, Jefferis, Gregory S.X.E., Bühler, Katja, Straw, Andrew D.
Publicado 2016

Systems Analysis of the Dynamic Inflammatory Response to Tissue Damage Reveals Spatiotemporal Properties of the Wound Attractant Gradient

por Weavers, Helen, Liepe, Juliane, Sim, Aaron, Wood, Will, Martin, Paul, Stumpf, Michael P.H.
Publicado 2016

Erk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell Identity

por Williams, Charles A.C., Fernandez-Alonso, Rosalia, Wang, Jinhua, Toth, Rachel, Gray, Nathanael S., Findlay, Greg M.
Publicado 2016

Phospho-dependent Accumulation of GABA(B)Rs at Presynaptic Terminals after NMDAR Activation

por Hannan, Saad, Gerrow, Kim, Triller, Antoine, Smart, Trevor G.
Publicado 2016

Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer

por Shlien, Adam, Raine, Keiran, Fuligni, Fabio, Arnold, Roland, Nik-Zainal, Serena, Dronov, Serge, Mamanova, Lira, Rosic, Andrej, Ju, Young Seok, Cooke, Susanna L., Ramakrishna, Manasa, Papaemmanuil, Elli, Davies, Helen R., Tarpey, Patrick S., Van Loo, Peter, Wedge, David C., Jones, David R., Martin, Sancha, Marshall, John, Anderson, Elizabeth, Hardy, Claire, Barbashina, Violetta, Aparicio, Samuel A.J.R., Sauer, Torill, Garred, Øystein, Vincent-Salomon, Anne, Mariani, Odette, Boyault, Sandrine, Fatima, Aquila, Langerød, Anita, Borg, Åke, Thomas, Gilles, Richardson, Andrea L., Børresen-Dale, Anne-Lise, Polyak, Kornelia, Stratton, Michael R., Campbell, Peter J.
Publicado 2016

Fascin Regulates Nuclear Movement and Deformation in Migrating Cells

por Jayo, Asier, Malboubi, Majid, Antoku, Susumu, Chang, Wakam, Ortiz-Zapater, Elena, Groen, Christopher, Pfisterer, Karin, Tootle, Tina, Charras, Guillaume, Gundersen, Gregg G., Parsons, Maddy
Publicado 2016

aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization

por Soriano, Erika V., Ivanova, Marina E., Fletcher, Georgina, Riou, Philippe, Knowles, Philip P., Barnouin, Karin, Purkiss, Andrew, Kostelecky, Brenda, Saiu, Peter, Linch, Mark, Elbediwy, Ahmed, Kjær, Svend, O’Reilly, Nicola, Snijders, Ambrosius P., Parker, Peter J., Thompson, Barry J., McDonald, Neil Q.
Publicado 2016

Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells

por Monteiro, Rui, Pinheiro, Philip, Joseph, Nicola, Peterkin, Tessa, Koth, Jana, Repapi, Emmanouela, Bonkhofer, Florian, Kirmizitas, Arif, Patient, Roger
Publicado 2016

Archaerhodopsin Selectively and Reversibly Silences Synaptic Transmission through Altered pH

por El-Gaby, Mohamady, Zhang, Yu, Wolf, Konstantin, Schwiening, Christof J., Paulsen, Ole, Shipton, Olivia A.
Publicado 2016

Genetic Predisposition to Chronic Lymphocytic Leukemia Is Mediated by a BMF Super-Enhancer Polymorphism

por Kandaswamy, Radhika, Sava, Georgina P., Speedy, Helen E., Beà, Sílvia, Martín-Subero, José I., Studd, James B., Migliorini, Gabriele, Law, Philip J., Puente, Xose S., Martín-García, David, Salaverria, Itziar, Gutiérrez-Abril, Jesús, López-Otín, Carlos, Catovsky, Daniel, Allan, James M., Campo, Elías, Houlston, Richard S.
Publicado 2016