A Functional Link between AMPK and Orexin Mediates the Effect of BMP8B on Energy Balance

por Martins, Luís, Seoane-Collazo, Patricia, Contreras, Cristina, González-García, Ismael, Martínez-Sánchez, Noelia, González, Francisco, Zalvide, Juan, Gallego, Rosalía, Diéguez, Carlos, Nogueiras, Rubén, Tena-Sempere, Manuel, López, Miguel
Publicado 2016

PTEN Loss in E-Cadherin-Deficient Mouse Mammary Epithelial Cells Rescues Apoptosis and Results in Development of Classical Invasive Lobular Carcinoma

por Boelens, Mirjam C., Nethe, Micha, Klarenbeek, Sjoerd, de Ruiter, Julian R., Schut, Eva, Bonzanni, Nicola, Zeeman, Amber L., Wientjens, Ellen, van der Burg, Eline, Wessels, Lodewyk, van Amerongen, Renée, Jonkers, Jos
Publicado 2016

The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity

por Damgaard, Rune Busk, Walker, Jennifer A., Marco-Casanova, Paola, Morgan, Neil V., Titheradge, Hannah L., Elliott, Paul R., McHale, Duncan, Maher, Eamonn R., McKenzie, Andrew N.J., Komander, David
Publicado 2016

NOTCH1 Inhibits Activation of ATM by Impairing the Formation of an ATM-FOXO3a-KAT5/Tip60 Complex

por Adamowicz, Marek, Vermezovic, Jelena, d’Adda di Fagagna, Fabrizio
Publicado 2016

Molecular Principles of Gene Fusion Mediated Rewiring of Protein Interaction Networks in Cancer

por Latysheva, Natasha S., Oates, Matt E., Maddox, Louis, Flock, Tilman, Gough, Julian, Buljan, Marija, Weatheritt, Robert J., Babu, M. Madan
Publicado 2016

Deep Proteome Analysis Identifies Age-Related Processes in C. elegans

por Narayan, Vikram, Ly, Tony, Pourkarimi, Ehsan, Murillo, Alejandro Brenes, Gartner, Anton, Lamond, Angus I., Kenyon, Cynthia
Publicado 2016

Comprehensive Identification of RNA-Binding Domains in Human Cells

por Castello, Alfredo, Fischer, Bernd, Frese, Christian K., Horos, Rastislav, Alleaume, Anne-Marie, Foehr, Sophia, Curk, Tomaz, Krijgsveld, Jeroen, Hentze, Matthias W.
Publicado 2016

UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome

por Hjerpe, Roland, Bett, John S., Keuss, Matthew J., Solovyova, Alexandra, McWilliams, Thomas G., Johnson, Clare, Sahu, Indrajit, Varghese, Joby, Wood, Nicola, Wightman, Melanie, Osborne, Georgina, Bates, Gillian P., Glickman, Michael H., Trost, Matthias, Knebel, Axel, Marchesi, Francesco, Kurz, Thimo
Publicado 2016

The Environmental Legacy of Modern Tropical Deforestation

por Rosa, Isabel M.D., Smith, Matthew J., Wearn, Oliver R., Purves, Drew, Ewers, Robert M.
Publicado 2016

Ultra-High Resolution 3D Imaging of Whole Cells

por Huang, Fang, Sirinakis, George, Allgeyer, Edward S., Schroeder, Lena K., Duim, Whitney C., Kromann, Emil B., Phan, Thomy, Rivera-Molina, Felix E., Myers, Jordan R., Irnov, Irnov, Lessard, Mark, Zhang, Yongdeng, Handel, Mary Ann, Jacobs-Wagner, Christine, Lusk, C. Patrick, Rothman, James E., Toomre, Derek, Booth, Martin J., Bewersdorf, Joerg
Publicado 2016

SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes

por Kupka, Sebastian, De Miguel, Diego, Draber, Peter, Martino, Luigi, Surinova, Silvia, Rittinger, Katrin, Walczak, Henning
Publicado 2016

mGluR-LTD at Excitatory and Inhibitory Synapses in the Lateral Habenula Tunes Neuronal Output

por Valentinova, Kristina, Mameli, Manuel
Publicado 2016

Synthetic Biology Platform for Sensing and Integrating Endogenous Transcriptional Inputs in Mammalian Cells

por Angelici, Bartolomeo, Mailand, Erik, Haefliger, Benjamin, Benenson, Yaakov
Publicado 2016

PML at Mitochondria-Associated Membranes Is Critical for the Repression of Autophagy and Cancer Development

por Missiroli, Sonia, Bonora, Massimo, Patergnani, Simone, Poletti, Federica, Perrone, Mariasole, Gafà, Roberta, Magri, Eros, Raimondi, Andrea, Lanza, Giovanni, Tacchetti, Carlo, Kroemer, Guido, Pandolfi, Pier Paolo, Pinton, Paolo, Giorgi, Carlotta
Publicado 2016

Structure of the Dual-Mode Wnt Regulator Kremen1 and Insight into Ternary Complex Formation with LRP6 and Dickkopf

por Zebisch, Matthias, Jackson, Verity A., Zhao, Yuguang, Jones, E. Yvonne
Publicado 2016

Host AMPK Is a Modulator of Plasmodium Liver Infection

por Ruivo, Margarida T. Grilo, Vera, Iset Medina, Sales-Dias, Joana, Meireles, Patrícia, Gural, Nil, Bhatia, Sangeeta N., Mota, Maria M., Mancio-Silva, Liliana
Publicado 2016

MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage Response

por Staples, Christopher J., Barone, Giancarlo, Myers, Katie N., Ganesh, Anil, Gibbs-Seymour, Ian, Patil, Abhijit A., Beveridge, Ryan D., Daye, Caroline, Beniston, Richard, Maslen, Sarah, Ahel, Ivan, Skehel, J. Mark, Collis, Spencer J.
Publicado 2016

Dynamics of Nucleosome Positioning Maturation following Genomic Replication

por Vasseur, Pauline, Tonazzini, Saphia, Ziane, Rahima, Camasses, Alain, Rando, Oliver J., Radman-Livaja, Marta
Publicado 2016

Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies

por Briney, Bryan, Sok, Devin, Jardine, Joseph G., Kulp, Daniel W., Skog, Patrick, Menis, Sergey, Jacak, Ronald, Kalyuzhniy, Oleksandr, de Val, Natalia, Sesterhenn, Fabian, Le, Khoa M., Ramos, Alejandra, Jones, Meaghan, Saye-Francisco, Karen L., Blane, Tanya R., Spencer, Skye, Georgeson, Erik, Hu, Xiaozhen, Ozorowski, Gabriel, Adachi, Yumiko, Kubitz, Michael, Sarkar, Anita, Wilson, Ian A., Ward, Andrew B., Nemazee, David, Burton, Dennis R., Schief, William R.
Publicado 2016

Structure of the Bacterial Sex F Pilus Reveals an Assembly of a Stoichiometric Protein-Phospholipid Complex

por Costa, Tiago R.D., Ilangovan, Aravindan, Ukleja, Marta, Redzej, Adam, Santini, Joanne M., Smith, Terry K., Egelman, Edward H., Waksman, Gabriel
Publicado 2016