ATM Localization and Heterochromatin Repair Depend on Direct Interaction of the 53BP1-BRCT(2) Domain with γH2AX

por Baldock, Robert A., Day, Matthew, Wilkinson, Oliver J., Cloney, Ross, Jeggo, Penelope A., Oliver, Antony W., Watts, Felicity Z., Pearl, Laurence H.
Publicado 2015

Brown Adipose Tissue Thermogenic Capacity Is Regulated by Elovl6

por Tan, Chong Yew, Virtue, Samuel, Bidault, Guillaume, Dale, Martin, Hagen, Rachel, Griffin, Julian L., Vidal-Puig, Antonio
Publicado 2015

LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes

por Draber, Peter, Kupka, Sebastian, Reichert, Matthias, Draberova, Helena, Lafont, Elodie, de Miguel, Diego, Spilgies, Lisanne, Surinova, Silvia, Taraborrelli, Lucia, Hartwig, Torsten, Rieser, Eva, Martino, Luigi, Rittinger, Katrin, Walczak, Henning
Publicado 2015

Specific Myosins Control Actin Organization, Cell Morphology, and Migration in Prostate Cancer Cells

por Makowska, Katarzyna A., Hughes, Ruth E., White, Kathryn J., Wells, Claire M., Peckham, Michelle
Publicado 2015

Population Genomics of Mycobacterium tuberculosis in Ethiopia Contradicts the Virgin Soil Hypothesis for Human Tuberculosis in Sub-Saharan Africa

por Comas, Iñaki, Hailu, Elena, Kiros, Teklu, Bekele, Shiferaw, Mekonnen, Wondale, Gumi, Balako, Tschopp, Rea, Ameni, Gobena, Hewinson, R. Glyn, Robertson, Brian D., Goig, Galo A., Stucki, David, Gagneux, Sebastien, Aseffa, Abraham, Young, Douglas, Berg, Stefan
Publicado 2015

Energy-Efficient Information Transfer by Visual Pathway Synapses

por Harris, Julia J., Jolivet, Renaud, Engl, Elisabeth, Attwell, David
Publicado 2015

Genetic Control over mtDNA and Its Relationship to Major Depressive Disorder

por Cai, Na, Li, Yihan, Chang, Simon, Liang, Jieqin, Lin, Chongyun, Zhang, Xiufei, Liang, Lu, Hu, Jingchu, Chan, Wharton, Kendler, Kenneth S., Malinauskas, Tomas, Huang, Guo-Jen, Li, Qibin, Mott, Richard, Flint, Jonathan
Publicado 2015

Activation of ULK Kinase and Autophagy by GABARAP Trafficking from the Centrosome Is Regulated by WAC and GM130

por Joachim, Justin, Jefferies, Harold B.J., Razi, Minoo, Frith, David, Snijders, Ambrosius P., Chakravarty, Probir, Judith, Delphine, Tooze, Sharon A.
Publicado 2015

Mother Centriole Distal Appendages Mediate Centrosome Docking at the Immunological Synapse and Reveal Mechanistic Parallels with Ciliogenesis

por Stinchcombe, Jane C., Randzavola, Lyra O., Angus, Karen L., Mantell, Judith M., Verkade, Paul, Griffiths, Gillian M.
Publicado 2015

Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance

por Menolfi, Demis, Delamarre, Axel, Lengronne, Armelle, Pasero, Philippe, Branzei, Dana
Publicado 2015

DGCR8 Acts as an Adaptor for the Exosome Complex to Degrade Double-Stranded Structured RNAs

por Macias, Sara, Cordiner, Ross A., Gautier, Philippe, Plass, Mireya, Cáceres, Javier F.
Publicado 2015

Differential DNA Methylation Analysis without a Reference Genome

por Klughammer, Johanna, Datlinger, Paul, Printz, Dieter, Sheffield, Nathan C., Farlik, Matthias, Hadler, Johanna, Fritsch, Gerhard, Bock, Christoph
Publicado 2015

Context-Specific Effects of TGF-β/SMAD3 in Cancer Are Modulated by the Epigenome

por Tufegdzic Vidakovic, Ana, Rueda, Oscar M., Vervoort, Stephin J., Sati Batra, Ankita, Goldgraben, Mae Akilina, Uribe-Lewis, Santiago, Greenwood, Wendy, Coffer, Paul J., Bruna, Alejandra, Caldas, Carlos
Publicado 2015

Condensin Relocalization from Centromeres to Chromosome Arms Promotes Top2 Recruitment during Anaphase

por Leonard, Joanne, Sen, Nicholas, Torres, Raul, Sutani, Takashi, Jarmuz, Adam, Shirahige, Katsuhiko, Aragón, Luis
Publicado 2015

Regulation of mRNA Levels by Decay-Promoting Introns that Recruit the Exosome Specificity Factor Mmi1

por Kilchert, Cornelia, Wittmann, Sina, Passoni, Monica, Shah, Sneha, Granneman, Sander, Vasiljeva, Lidia
Publicado 2015

Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA

por Liu, Yijin, Freeman, Alasdair D.J., Déclais, Anne-Cécile, Wilson, Timothy J., Gartner, Anton, Lilley, David M.J.
Publicado 2015

Phosphorylation of an HP1-like Protein Regulates Heterochromatin Body Assembly for DNA Elimination

por Kataoka, Kensuke, Mochizuki, Kazufumi
Publicado 2015

Nucleotide Pool Depletion Induces G-Quadruplex-Dependent Perturbation of Gene Expression

por Papadopoulou, Charikleia, Guilbaud, Guillaume, Schiavone, Davide, Sale, Julian E.
Publicado 2015

Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization

por del Pozo Martin, Yaiza, Park, Danielle, Ramachandran, Anassuya, Ombrato, Luigi, Calvo, Fernando, Chakravarty, Probir, Spencer-Dene, Bradley, Derzsi, Stefanie, Hill, Caroline S., Sahai, Erik, Malanchi, Ilaria
Publicado 2015

Crystal Structure of the Herpesvirus Nuclear Egress Complex Provides Insights into Inner Nuclear Membrane Remodeling

por Zeev-Ben-Mordehai, Tzviya, Weberruß, Marion, Lorenz, Michael, Cheleski, Juliana, Hellberg, Teresa, Whittle, Cathy, El Omari, Kamel, Vasishtan, Daven, Dent, Kyle C., Harlos, Karl, Franzke, Kati, Hagen, Christoph, Klupp, Barbara G., Antonin, Wolfram, Mettenleiter, Thomas C., Grünewald, Kay
Publicado 2015