Disrupted PI3K p110δ Signaling Dysregulates Maternal Immune Cells and Increases Fetal Mortality In Mice

por Kieckbusch, Jens, Balmas, Elisa, Hawkes, Delia A., Colucci, Francesco
Publicado 2015

Bidirectional Control of Synaptic GABA(A)R Clustering by Glutamate and Calcium

por Bannai, Hiroko, Niwa, Fumihiro, Sherwood, Mark W., Shrivastava, Amulya Nidhi, Arizono, Misa, Miyamoto, Akitoshi, Sugiura, Kotomi, Lévi, Sabine, Triller, Antoine, Mikoshiba, Katsuhiko
Publicado 2015

MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199

por Benito, Juliana M., Godfrey, Laura, Kojima, Kensuke, Hogdal, Leah, Wunderlich, Mark, Geng, Huimin, Marzo, Isabel, Harutyunyan, Karine G., Golfman, Leonard, North, Phillip, Kerry, Jon, Ballabio, Erica, Chonghaile, Triona Ní, Gonzalo, Oscar, Qiu, Yihua, Jeremias, Irmela, Debose, LaKiesha, O’Brien, Eric, Ma, Helen, Zhou, Ping, Jacamo, Rodrigo, Park, Eugene, Coombes, Kevin R., Zhang, Nianxiang, Thomas, Deborah A., O’Brien, Susan, Kantarjian, Hagop M., Leverson, Joel D., Kornblau, Steven M., Andreeff, Michael, Müschen, Markus, Zweidler-McKay, Patrick A., Mulloy, James C., Letai, Anthony, Milne, Thomas A., Konopleva, Marina
Publicado 2015

Nuclear Retention of mRNA in Mammalian Tissues

por Bahar Halpern, Keren, Caspi, Inbal, Lemze, Doron, Levy, Maayan, Landen, Shanie, Elinav, Eran, Ulitsky, Igor, Itzkovitz, Shalev
Publicado 2015

Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts

por Calvo, Fernando, Ranftl, Romana, Hooper, Steven, Farrugia, Aaron J., Moeendarbary, Emad, Bruckbauer, Andreas, Batista, Facundo, Charras, Guillaume, Sahai, Erik
Publicado 2015

Structural Basis of Vesicle Formation at the Inner Nuclear Membrane

por Hagen, Christoph, Dent, Kyle C., Zeev-Ben-Mordehai, Tzviya, Grange, Michael, Bosse, Jens B., Whittle, Cathy, Klupp, Barbara G., Siebert, C. Alistair, Vasishtan, Daven, Bäuerlein, Felix J.B., Cheleski, Juliana, Werner, Stephan, Guttmann, Peter, Rehbein, Stefan, Henzler, Katja, Demmerle, Justin, Adler, Barbara, Koszinowski, Ulrich, Schermelleh, Lothar, Schneider, Gerd, Enquist, Lynn W., Plitzko, Jürgen M., Mettenleiter, Thomas C., Grünewald, Kay
Publicado 2015

DNA Entry into and Exit out of the Cohesin Ring by an Interlocking Gate Mechanism

por Murayama, Yasuto, Uhlmann, Frank
Publicado 2015

Uncovering the Number and Clonal Dynamics of Mesp1 Progenitors during Heart Morphogenesis

por Chabab, Samira, Lescroart, Fabienne, Rulands, Steffen, Mathiah, Navrita, Simons, Benjamin D., Blanpain, Cédric
Publicado 2015

Mevalonate Pathway Regulates Cell Size Homeostasis and Proteostasis through Autophagy

por Miettinen, Teemu P., Björklund, Mikael
Publicado 2015

The Cost of Protein Production

por Kafri, Moshe, Metzl-Raz, Eyal, Jona, Ghil, Barkai, Naama
Publicado 2015

Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue

por Erami, Zahra, Herrmann, David, Warren, Sean C., Nobis, Max, McGhee, Ewan J., Lucas, Morghan C., Leung, Wilfred, Reischmann, Nadine, Mrowinska, Agata, Schwarz, Juliane P., Kadir, Shereen, Conway, James R.W., Vennin, Claire, Karim, Saadia A., Campbell, Andrew D., Gallego-Ortega, David, Magenau, Astrid, Murphy, Kendelle J., Ridgway, Rachel A., Law, Andrew M., Walters, Stacey N., Grey, Shane T., Croucher, David R., Zhang, Lei, Herzog, Herbert, Hardeman, Edna C., Gunning, Peter W., Ormandy, Christopher J., Evans, T.R. Jeffry, Strathdee, Douglas, Sansom, Owen J., Morton, Jennifer P., Anderson, Kurt I., Timpson, Paul
Publicado 2015

Reversible Optogenetic Control of Subcellular Protein Localization in a Live Vertebrate Embryo

por Buckley, Clare E., Moore, Rachel E., Reade, Anna, Goldberg, Anna R., Weiner, Orion D., Clarke, Jonathan D.W.
Publicado 2016

Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia

por Cheung, Ngai, Fung, Tsz Kan, Zeisig, Bernd B., Holmes, Katie, Rane, Jayant K., Mowen, Kerri A., Finn, Michael G., Lenhard, Boris, Chan, Li Chong, So, Chi Wai Eric
Publicado 2016

EpiTools: An Open-Source Image Analysis Toolkit for Quantifying Epithelial Growth Dynamics

por Heller, Davide, Hoppe, Andreas, Restrepo, Simon, Gatti, Lorenzo, Tournier, Alexander L., Tapon, Nicolas, Basler, Konrad, Mao, Yanlan
Publicado 2016

Dissociable Learning Processes Underlie Human Pain Conditioning

por Zhang, Suyi, Mano, Hiroaki, Ganesh, Gowrishankar, Robbins, Trevor, Seymour, Ben
Publicado 2016

RSL Class I Genes Controlled the Development of Epidermal Structures in the Common Ancestor of Land Plants

por Proust, Hélène, Honkanen, Suvi, Jones, Victor A.S., Morieri, Giulia, Prescott, Helen, Kelly, Steve, Ishizaki, Kimitsune, Kohchi, Takayuki, Dolan, Liam
Publicado 2016

Shadow Enhancers Are Pervasive Features of Developmental Regulatory Networks

por Cannavò, Enrico, Khoueiry, Pierre, Garfield, David A., Geeleher, Paul, Zichner, Thomas, Gustafson, E. Hilary, Ciglar, Lucia, Korbel, Jan O., Furlong, Eileen E.M.
Publicado 2016

Human-Mouse Chimerism Validates Human Stem Cell Pluripotency

por Mascetti, Victoria L., Pedersen, Roger A.
Publicado 2016

PrimPol Is Required for Replicative Tolerance of G Quadruplexes in Vertebrate Cells

por Schiavone, Davide, Jozwiakowski, Stanislaw K., Romanello, Marina, Guilbaud, Guillaume, Guilliam, Thomas A., Bailey, Laura J., Sale, Julian E., Doherty, Aidan J.
Publicado 2016

Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of PB2 Domains

por Thierry, Eric, Guilligay, Delphine, Kosinski, Jan, Bock, Thomas, Gaudon, Stephanie, Round, Adam, Pflug, Alexander, Hengrung, Narin, El Omari, Kamel, Baudin, Florence, Hart, Darren J., Beck, Martin, Cusack, Stephen
Publicado 2016